Experimental Pain in Human Temporal Muscle Induced by Hypertonic Saline, Potassium and Acidity

Cephalalgia ◽  
1992 ◽  
Vol 12 (2) ◽  
pp. 101-106 ◽  
Author(s):  
Kai Jensen ◽  
Michael Norup
Keyword(s):  
Pain Intensity ◽  
Potassium Chloride ◽  
Hypertonic Saline ◽  
Pain Threshold ◽  
Isotonic Saline ◽  
Pressure Pain Threshold ◽  
Experimental Pain ◽  
Ordinal Scale ◽  
Temporal Muscle ◽  
Pressure Pain

The study was aimed at developing a reference model for experimental pain and tenderness in the human temporal muscle by the local injection of hypertonic saline, potassium chloride and acidic phosphate buffer, using isotonic saline as control. The design was randomized and double-blind. Twenty healthy subjects had 0.2 ml test solution injected into one temporal muscle and saline into the other. Following each injection, pain was rated on a 10-point ordinal scale and pressure-pain thresholds were measured every minute for 10 min by a pressure algometer. Hypertonic saline ( n = 11) and potassium chloride ( n = 12) induced significantly more pain than isotonic saline ( ANOVA, p < 0.0001). Compared to control injections, hypertonic saline and potassium chloride induced a significant reduction in pressure-pain threshold (ANOVA, p < 0.0001 and p < 0.05). Forty-eight percent of the injections led to the referral of pain most often to the jaws. A positive correlation between the relative occurrence of referred pain and pain intensity was observed ( p < 0.001) as was a negative correlation between the decrease in pressure-pain threshold and pain intensity ( p < 0.05).

scholarly journals Percutaneous Fascia Release for Treating Chronic Recurrent Gluteal Myofascial Pain—A Pilot Study of a New Technique

2015 ◽  
Vol 4 ◽  
pp. RPO.S30483 ◽  
Author(s):  
Hsin-Shui Chen ◽  
Ming-Ta Lin ◽  
Chang-Zern Hong ◽  
Yueh-Ling Hsieh ◽  
Li-Wei Chou
Keyword(s):  
Pilot Study ◽  
Pain Intensity ◽  
Pain Threshold ◽  
Myofascial Pain ◽  
Pressure Pain Threshold ◽  
Small Sample ◽  
Myofascial Trigger Points ◽  
Pressure Pain ◽  
Hip Abduction ◽  
Abduction Strength

Objective To investigate the therapeutic effectiveness of percutaneous fascia release to treat chronic recurrent gluteal myofascial pain related to recurrent tendonitis or bursitis at the attachment sites. Methods Five patients (three males, two females; aged 48.6 ± 8.9 years) with myofascial trigger points in the gluteus medius muscle were treated. Outcome measures, including pain intensity, pressure pain threshold, and the relative strength of hip abduction, were assessed before, immediately after, and six months after the treatment. The data measured before and after treatment (different times) on visual analog scale, pressure pain threshold, and relative hip abduction strength were analyzed by Wilcoxon signed-rank test and paired t-test, respectively, for the comparisons between time points. Results Reduction in pain intensity and increase in the pressure pain threshold and the relative hip abduction strength were found in all five patients after treatment when compared with those of before treatment ( P < 0.05). Moreover, all of these improvements existed for at least six months ( P > 0.05). Conclusions Percutaneous fascia release of gluteal muscle insertion sites can be used to treat chronic gluteal pain related to subtrochanteric bursitis to avoid recurrence, if other treatment cannot control the recurrence, although this was demonstrated only on a small sample size without control and blind assessment in the pilot study.

scholarly journals The Distinction of Hot Herbal Compress, Hot Compress, and Topical Diclofenac as Myofascial Pain Syndrome Treatment

2018 ◽  
Vol 23 ◽  
pp. 215658721775345 ◽  
Author(s):  
Jurairat Boonruab ◽  
Netraya Nimpitakpong ◽  
Watchara Damjuti
Keyword(s):  
Quality Of Life ◽  
Pain Intensity ◽  
Range Of Motion ◽  
Pain Threshold ◽  
Pressure Pain Threshold ◽  
Pressure Pain ◽  
Cervical Range Of Motion ◽  
Topical Diclofenac ◽  
Hot Compress

This randomized controlled trial aimed to investigate the distinctness after treatment among hot herbal compress, hot compress, and topical diclofenac. The registrants were equally divided into groups and received the different treatments including hot herbal compress, hot compress, and topical diclofenac group, which served as the control group. After treatment courses, Visual Analog Scale and 36-Item Short Form Health survey were, respectively, used to establish the level of pain intensity and quality of life. In addition, cervical range of motion and pressure pain threshold were also examined to identify the motional effects. All treatments showed significantly decreased level of pain intensity and increased cervical range of motion, while the intervention groups exhibited extraordinary capability compared with the topical diclofenac group in pressure pain threshold and quality of life. In summary, hot herbal compress holds promise to be an efficacious treatment parallel to hot compress and topical diclofenac.

scholarly journals Myalgia in 30 Patients with Suspected Myopathy

2020 ◽  
Vol 17 (7) ◽  
pp. 2502
Author(s):  
Diana Lehmann Urban ◽  
Elizabeth Lehmann ◽  
Leila Motlagh Scholle ◽  
Torsten Kraya
Keyword(s):  
Pain Intensity ◽  
Polymyalgia Rheumatica ◽  
Pain Sensitivity ◽  
Pain Threshold ◽  
Neuromuscular Disorders ◽  
Pressure Pain Threshold ◽  
Neuromuscular Disorder ◽  
Weak Correlation ◽  
Pressure Pain ◽  
Significant Difference

Background: In patients with neuromuscular disorder, only little data of myalgia frequency and characterization exists. To date, only a weak correlation between pain intensity and pressure pain threshold has been found, and it remains enigmatic whether high pain intensity levels are equivalent to high pain sensitivity levels in neuromuscular disorders. Methods: 30 sequential patients with suspected neuromuscular disorder and myalgia were analyzed with regard to myalgia characteristics and clinical findings, including symptoms of depression and anxiety and pain- threshold. Results: A neuromuscular disorder was diagnosed in 14/30 patients. Muscular pain fasciculation syndrome (MPFS) without evidence for myopathy or myositis was diagnosed in 10/30 patients and 6/30 patients were diagnosed with pure myalgia without evidence for a neuromuscular disorder (e.g., myopathy, myositis, MPFS, polymyalgia rheumatica). Highest median pain scores were found in patients with pure myalgia and polymyalgia rheumatica. Pressure pain threshold measurement showed a significant difference between patients and controls in the biceps brachii muscle. Conclusion: Only a weak correlation between pain intensity and pressure pain threshold has been suggested, which is concordant with our results. The hypothesis that high pain intensity levels are equivalent to high pain sensitivity levels was not demonstrated.

scholarly journals Percutaneous Soft Tissue Release for Treating Chronic Recurrent Myofascial Pain Associated with Lateral Epicondylitis: 6 Case Studies

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Ming-Ta Lin ◽  
Li-Wei Chou ◽  
Hsin-Shui Chen ◽  
Mu-Jung Kao
Keyword(s):  
Soft Tissue ◽  
Pain Intensity ◽  
Pain Threshold ◽  
Myofascial Pain ◽  
Pressure Pain Threshold ◽  
Lateral Epicondylitis ◽  
Soft Tissue Release ◽  
Recurrent Pain ◽  
Myofascial Trigger Points ◽  
Pressure Pain

Objective. The purpose of this pilot study is to investigate the effectiveness of the percutaneous soft tissue release for the treatment of recurrent myofascial pain in the forearm due to recurrent lateral epicondylitis.Methods. Six patients with chronic recurrent pain in the forearm with myofascial trigger points (MTrPs) due to chronic lateral epicondylitis were treated with percutaneous soft tissue release of Lin’s technique. Pain intensity (measured with a numerical pain rating scale), pressure pain threshold (measured with a pressure algometer), and grasping strength (measured with a hand dynamometer) were assessed before, immediately after, and 3 months and 12 months after the treatment.Results. For every individual case, the pain intensity was significantly reduced(P<0.01)and the pressure pain threshold and the grasping strength were significantly increased(P<0.01)immediately after the treatment. This significant effectiveness lasts for at least one year.Conclusions. It is suggested that percutaneous soft tissue release can be used for treating chronic recurrent lateral epicondylitis to avoid recurrence, if other treatment, such as oral anti-inflammatory medicine, physical therapy, or local steroid injection, cannot control the recurrent pain.

scholarly journals Immediate Effects of Region-Specific and Non–Region-Specific Spinal Manipulative Therapy in Patients With Chronic Low Back Pain: A Randomized Controlled Trial

2013 ◽  
Vol 93 (6) ◽  
pp. 748-756 ◽  
Author(s):  
Ronaldo Fernando de Oliveira ◽  
Richard Eloin Liebano ◽  
Lucíola da Cunha Menezes Costa ◽  
Lívia Leticia Rissato ◽  
Leonardo Oliveira Pena Costa
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Pain Intensity ◽  
Spinal Manipulation ◽  
Pain Threshold ◽  
Controlled Trial ◽  
Pressure Pain Threshold ◽  
Low Back ◽  
Pressure Pain ◽  
Upper Thoracic

Background Manual therapists typically advocate the need for a detailed clinical examination to decide which vertebral level should be manipulated in patients with low back pain. However, it is unclear whether spinal manipulation needs to be specific to a vertebral level. Objective The purpose of this study was to analyze the immediate effects of a single, region-specific spinal manipulation defined during the clinical examination versus a single non–region-specific spinal manipulation (applied on an upper thoracic vertebra) in patients with chronic nonspecific low back pain for the outcome measures of pain intensity and pressure pain threshold at the time of the assessment. Design This was a 2-arm, prospectively registered, randomized controlled trial with a blinded assessor. Setting The study was conducted in an outpatient physical therapy clinic in Brazil. Patients The study participants were 148 patients with chronic nonspecific low back pain (with pain duration of at least 12 weeks). Randomization The randomization schedule was generated by an independent statistician and was concealed by using consecutively numbered, sealed, opaque envelopes. Interventions A single high-velocity manipulation was administered to the upper thoracic region of the participants allocated to the non–region-specific manipulation group and to the painful lumbar levels of the participants allocated to the region-specific manipulation group. Measurements Pain intensity was measured by a 0 to 10 numeric pain rating scale. Pressure pain threshold was measured using a pressure algometer. Limitations It was not possible to blind the therapist and participants. Results A total of 148 patients participated in the study (74 in each group). There was no loss to follow-up. Both groups improved in terms of immediate decrease of pain intensity; however, no between-group differences were observed. The between-group difference for pain intensity and pressure pain threshold were 0.50 points (95% confidence interval=−0.10 to 1.10) and −1.78 points (95% confidence interval=−6.40 to 2.82), respectively. No adverse reactions were observed. Conclusion The immediate changes in pain intensity and pressure pain threshold after a single high-velocity manipulation do not differ by region-specific versus non–region-specific manipulation techniques in patients with chronic low back pain.

Correlation Between Severity of Temporomandibular Disorder, Pain Intensity, and Pressure Pain Threshold

2018 ◽  
Vol 41 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Carolina Marciela Herpich ◽  
Cid André Fidelis de Paula Gomes ◽  
Almir Vieira Dibai-Filho ◽  
Fabiano Politti ◽  
Cesário da Silva Souza ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Pain Threshold ◽  
Temporomandibular Disorder ◽  
Pressure Pain Threshold ◽  
Pressure Pain

Effectiveness of low-level laser therapy on pain intensity, pressure pain threshold, and SF-MPQ indexes of women with myofascial pain

2017 ◽  
Vol 32 (2) ◽  
pp. 419-428 ◽  
Author(s):  
Laís Valencise Magri ◽  
Vinícius Almeida Carvalho ◽  
Flávia Cássia Cabral Rodrigues ◽  
César Bataglion ◽  
Christie Ramos Andrade Leite-Panissi
Keyword(s):  
Pain Intensity ◽  
Laser Therapy ◽  
Pain Threshold ◽  
Myofascial Pain ◽  
Pressure Pain Threshold ◽  
Low Level Laser Therapy ◽  
Pressure Pain ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Muscle Pain Intensity and Pressure Pain Threshold Changes in Different Periods of Stroke Patients

2014 ◽  
Vol 93 (4) ◽  
pp. 299-309 ◽  
Author(s):  
Chu-Hsu Lin ◽  
Kai-Hua Chen ◽  
Chia-Hao Chang ◽  
Chien-Min Chen ◽  
Ying Chih Huang ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Muscle Pain ◽  
Pain Threshold ◽  
Pressure Pain Threshold ◽  
Stroke Patients ◽  
Pressure Pain

Local hyperalgesia, normal endogenous modulation with pain report beyond its origin: a pilot study prompting further exploration into plantar fasciopathy

2020 ◽  
Vol 20 (2) ◽  
pp. 375-385
Author(s):  
Henrik Riel ◽  
Melanie L. Plinsinga ◽  
Rebecca Mellor ◽  
Shellie A. Boudreau ◽  
Viana Vuvan ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Pain Threshold ◽  
Pressure Pain Threshold ◽  
Plantar Fascia ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Pain Processing ◽  
Pain Thresholds ◽  
Pressure Pain ◽  
Plantar Fasciopathy

AbstractBackground and aimsPersistent tendinopathies were previously considered solely as peripheral conditions affecting the local tendinous tissue until quantitative sensory testing identified involvement of altered pain processing. In similar fashion, pain in patients with persistent plantar fasciopathy may also involve more than local tissue. The aim of this pilot study was to investigate potential differences in conditioned pain modulation and pressure and thermal pain thresholds, between individuals with PF and healthy pain-free controls, as a precursor to a larger-scale study.MethodsWe assessed 16 individuals with plantar fasciopathy and 11 pain-free controls. Plantar fasciopathy diagnosis was: palpation pain of the medial calcaneal tubercle or the proximal plantar fascia, duration ≥3 months, pain intensity ≥2/10, and ultrasound-measured plantar fascia thickness ≥4 mm. Quantitative sensory tests were performed locally at the plantar heel and remotely on the ipsilateral elbow. Assessments included pain thresholds for pressure, heat and cold, and conditioned pain modulation measured as change in local resting pressure pain threshold with cold water hand immersion. Participants rated pain intensity at pain threshold. Additionally, the area and distribution of plantar fasciopathy pain was drawn on a digital body chart of the lower limbs. Descriptive analyses were performed and between-group differences/effects expressed as standardised mean differences (d).ResultsThere was no conditioned pain modulation difference between participants with plantar fasciopathy and controls (d = 0.1). Largest effects were on local pressure pain threshold and reported pain intensity on pressure pain threshold (d > 1.8) followed by pain intensity for heat and cold pain thresholds (d = 0.3–1.5). According to the digital body chart, pain area extended beyond the plantar heel.ConclusionsThe unlikelihood of a difference in conditioned pain modulation yet a pain area extending beyond the plantar heel provide a basis for exploring altered pain processing in a larger-scale study.ImplicationsThis was the first study to investigate the presence of altered pain processing in individuals with plantar fasciopathy using a conditioned pain modulation paradigm and thermal pain thresholds. We found no indication of an altered pain processing based on these measures, however, patients rated pain higher on thresholds compared to controls which may be important to clinical practice and warrants further exploration in the future.

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