A method for estimating hepatitis B virus incidence rates in volunteer blood donors. National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study

Transfusion ◽  
1997 ◽  
Vol 37 (6) ◽  
pp. 634-640 ◽  
Author(s):  
JJ Korelitz ◽  
MP Busch ◽  
SH Kleinman ◽  
AE Williams ◽  
RO Gilcher ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Blood Donors ◽  
Incidence Rates ◽  
Blood Institute ◽  
National Heart ◽  
Virus Incidence ◽  
B Virus ◽  
National Heart Lung

Hepatitis B virus DNA in serum of ‘anti-HBc only’-positive healthy Lebanese blood donors: significance and possible implications

2007 ◽  
Vol 66 (3) ◽  
pp. 278-282 ◽  
Author(s):  
M. El-Zaatari ◽  
H. Kazma ◽  
M. Naboulsi-Majzoub ◽  
M. Haidar ◽  
F. Ramlawi ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Virus Dna ◽  
B Virus

Contrasting patterns and frequency of antibodies to the surface, core, and e antigens of hepatitis b virus in blood donors and in homosexual patients

1980 ◽  
Vol 6 (4) ◽  
pp. 323-332 ◽  
Author(s):  
R.S. Tedder ◽  
C.H. Cameron ◽  
Ruth Wilson-Croome ◽  
D.R. Howell ◽  
Anne Colgrove ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Blood Donors ◽  
B Virus

scholarly journals Prevalence of hepatitis B virus infection among blood donors at the Tamale Teaching Hospital, Ghana (2009)

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Julius Tieroyaare Dongdem ◽  
Sylvanus Kampo ◽  
Ireneous N Soyiri ◽  
Patrick Nsobila Asebga ◽  
Juventus B Ziem ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Teaching Hospital ◽  
Blood Donors ◽  
Hepatitis B Virus Infection ◽  
B Virus ◽  
Tamale Teaching Hospital

scholarly journals Hepatitis B Virus Pre-S Gene Deletions and Pre-S Deleted Proteins: Clinical and Molecular Implications in Hepatocellular Carcinoma

Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 862
Author(s):  
Yueh-Te Lin ◽  
Long-Bin Jeng ◽  
Wen-Ling Chan ◽  
Ih-Jen Su ◽  
Chiao-Fang Teng
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Molecular Mechanisms ◽  
Incidence Rates ◽  
Gene Deletions ◽  
S Gene ◽  
B Virus ◽  
Potential Applications ◽  
Prevention And Therapy

Hepatocellular carcinoma (HCC) is one of the most frequent and fatal human cancers worldwide and its development and prognosis are intimately associated with chronic infection with hepatitis B virus (HBV). The identification of genetic mutations and molecular mechanisms that mediate HBV-induced tumorigenesis therefore holds promise for the development of potential biomarkers and targets for HCC prevention and therapy. The presence of HBV pre-S gene deletions in the blood and the expression of pre-S deleted proteins in the liver tissues of patients with chronic hepatitis B and HBV-related HCC have emerged as valuable biomarkers for higher incidence rates of HCC development and a higher risk of HCC recurrence after curative surgical resection, respectively. Moreover, pre-S deleted proteins are regarded as important oncoproteins that activate multiple signaling pathways to induce DNA damage and promote growth and proliferation in hepatocytes, leading to HCC development. The signaling molecules dysregulated by pre-S deleted proteins have also been validated as potential targets for the prevention of HCC development. In this review, we summarize the clinical and molecular implications of HBV pre-S gene deletions and pre-S deleted proteins in HCC development and recurrence and highlight their potential applications in HCC prevention and therapy.

Occult Hepatitis B Virus Infection Among Blood Donors of North India

2007 ◽  
Vol 4 (4) ◽  
pp. 339-342
Author(s):  
R.N. Makroo ◽  
V. Raina ◽  
M. Chowdhry ◽  
M. Pathuppalli
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Blood Donors ◽  
North India ◽  
Hepatitis B Virus Infection ◽  
Occult Hepatitis ◽  
B Virus ◽  
Occult Hepatitis B

scholarly journals Knowledge and Attitude of Blood Donors Towards Hepatitis B Virus Risk Behaviour in Ikenne Local Government Area, Ogun State, Nigeria

2021 ◽  
Vol 1 (1) ◽  
pp. 93-104
Author(s):  
Adeyemo O.F. ◽  
Olugasa B.O. ◽  
Olarinmoye A. ◽  
Betiku A.
Keyword(s):  
Hepatitis B Virus ◽  
Local Government ◽  
Hepatitis B ◽  
Blood Donors ◽  
Risk Behaviour ◽  
Local Government Area ◽  
Positive Correlation ◽  
Ogun State ◽  
B Virus ◽  
Knowledge And Attitude

Hepatitis B virus (HBV) infection poses a major global health concern, responsible for estimated 500,000 to 1.2 million human deaths each year. The clinical manifestations of HBV-related deaths that usually arise after chronic-hepatitis include liver cirrhosis and hepatocellular carcinoma. The transfusion of blood is a critical risk point for inadvertent transmission of Hepatitis B virus at emergency healthcare points. This poses a significant public health challenge especially in developing countries. The impact of this challenge in Ikenne Local Government area is yet to be estimated. This study was designed to assess the level of knowledge and attitude of blood donors in the four major towns in Ikenne Local Government Area of Ogun State, Nigeria. A questionnaire survey enlisted 143 blood donors at selected blood banks in Ikenne, Ilishan, Iperu and Irolu towns in Ikenne Local Government Area, Ogun State, from February 4th to March 24th, 2021. Data collected were summarized using descriptive and correlation test statistics. Some 120 (93.9%) of the respondents were 18-34 years old. Unpaid donors accounted for 102 (78%) of the respondents. 2.8% of the respondents were confirmed positive for Hepatitis B virus before. Some 113 (86.9%) agreed that people should freely go for laboratory screening. Two-third 82 (63.1%) of the respondents indicated they knew where to get screened. Respondents’ knowledge was scored 2.423 ± 0.963, while a weak positive correlation was found between respondents’ knowledge and their risk behaviour (R = 0.296; P = <0.0001). The mean ± standard deviation of attitude of respondents was 4.207 ± 0.859, while a weak positive correlation was found between respondents’ Attitude and their risk behaviour (R = 0.225; P = < 0.010). Blood donors previously screened for the virus in general had better knowledge and behavioural attitudes that were compliant with Hepatitis B prevention, compared with previously unscreened individuals who exhibited high risk behaviour to the virus.

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