scholarly journals Astrophotonics: Processing starlight

2021 ◽  
Vol 52 (1) ◽  
pp. 22-24
Author(s):  
Aline N. Dinkelaker ◽  
Aashia Rahman
Keyword(s):  
Next Generation ◽  
New Era ◽  
Astronomical Instruments ◽  
Large Telescopes

The field of astrophotonics has been fostering photonic innovations critical and unique to astronomical applications for several years. As we are about to embark on the new era of extremely large telescopes, astrophotonics is poised to become an integral part of the next generation astronomical instruments.

A Service-Oriented User Interface for the Next Generation Web

2013 ◽  
pp. 192-208
Author(s):  
Shiping Chen ◽  
Surya Nepal
Keyword(s):  
User Interface ◽  
Web Service ◽  
Service Composition ◽  
Interface Design ◽  
Cost Model ◽  
Prototype System ◽  
Next Generation ◽  
New Era ◽  
Service Oriented ◽  
User Tasks

The Web enters a new era where contents are to take the back seat and services will take the driver seat to form a service-oriented Web. This paper presents a service-oriented user interface design for the next generation Web. The design leverages the advances of semantic Web and service composition technologies to provide an intelligent and generic user interface to query, compose and execute Web services for a variety of user tasks. First, a simple cost model is developed for estimating the development and learning overheads of Web service interfaces for service-oriented applications as the motivation of this work. Then, the authors present the design of the service-oriented browser and discuss the enabling technologies. A prototype system is developed using existing technologies and standards as a proof of concept.

A Service-Oriented User Interface for the Next Generation Web

2011 ◽  
Vol 2 (2) ◽  
pp. 60-76
Author(s):  
Shiping Chen ◽  
Surya Nepal
Keyword(s):  
User Interface ◽  
Interface Design ◽  
Cost Model ◽  
Prototype System ◽  
Proof Of Concept ◽  
Next Generation ◽  
New Era ◽  
Back Seat ◽  
Service Oriented ◽  
User Tasks

The Web enters a new era where contents are to take the back seat and services will take the driver seat to form a service-oriented Web. This paper presents a service-oriented user interface design for the next generation Web. The design leverages the advances of semantic Web and service composition technologies to provide an intelligent and generic user interface to query, compose and execute Web services for a variety of user tasks. First, a simple cost model is developed for estimating the development and learning overheads of Web service interfaces for service-oriented applications as the motivation of this work. Then, the authors present the design of the service-oriented browser and discuss the enabling technologies. A prototype system is developed using existing technologies and standards as a proof of concept.

scholarly journals New Era for Next-Generation Sequencing in Japan

Cancers ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 742 ◽  
Author(s):  
Masayuki Takeda ◽  
Kazuko Sakai ◽  
Takayuki Takahama ◽  
Kazuya Fukuoka ◽  
Kazuhiko Nakagawa ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Next Generation Sequencing ◽  
Solid Tumor ◽  
Recent Progress ◽  
Medical Curriculum ◽  
Next Generation ◽  
Multiple Cancer ◽  
New Era ◽  
Gene Panels ◽  
Generation Sequencing

Recent progress in understanding the molecular basis of cancer—including the discovery of cancer-associated genes such as oncogenes and tumor suppressor genes—has suggested that cancer can become a treatable disease. The identification of driver oncogenes such as EGFR, ALK, ROS1, BRAF and HER2 has already been successfully translated into clinical practice for individuals with solid tumor. Next-generation sequencing (NGS) technologies have led to the ability to test for multiple cancer-related genes at once with a small amount of cells and tissues. In Japan, several hospitals have started NGS-based mutational profiling screening in patients with solid tumor in order to guide patients to relevant clinical trials. The Ministry of Health, Labor, and Welfare of Japan has also approved several cancer gene panels for use in clinical practice. However, there is an urgent need to develop a medical curriculum of clinical variant interpretation and reporting. We review recent progress in the implementation of NGS in Japan.

Next-generation stem cells — ushering in a new era of cell-based therapies

2020 ◽  
Vol 19 (7) ◽  
pp. 463-479 ◽  
Author(s):  
Erin A. Kimbrel ◽  
Robert Lanza
Keyword(s):  
Stem Cells ◽  
Next Generation ◽  
New Era

scholarly journals Metagenomic Pyrosequencing and Microbial Identification

2009 ◽  
Vol 55 (5) ◽  
pp. 856-866 ◽  
Author(s):  
Joseph F Petrosino ◽  
Sarah Highlander ◽  
Ruth Ann Luna ◽  
Richard A Gibbs ◽  
James Versalovic
Keyword(s):  
Human Microbiome ◽  
Human Microbiome Project ◽  
Amplicon Sequencing ◽  
16S Rrna Genes ◽  
Rrna Genes ◽  
Next Generation ◽  
New Era ◽  
Microbial Identification ◽  
Core Technology ◽  
Dna Pyrosequencing

Abstract Background: The Human Microbiome Project has ushered in a new era for human metagenomics and high-throughput next-generation sequencing strategies. Content: This review describes evolving strategies in metagenomics, with a special emphasis on the core technology of DNA pyrosequencing. The challenges of microbial identification in the context of microbial populations are discussed. The development of next-generation pyrosequencing strategies and the technical hurdles confronting these methodologies are addressed. Bioinformatics-related topics include taxonomic systems, sequence databases, sequence-alignment tools, and classifiers. DNA sequencing based on 16S rRNA genes or entire genomes is summarized with respect to potential pyrosequencing applications. Summary: Both the approach of 16S rDNA amplicon sequencing and the whole-genome sequencing approach may be useful for human metagenomics, and numerous bioinformatics tools are being deployed to tackle such vast amounts of microbiological sequence diversity. Metagenomics, or genetic studies of microbial communities, may ultimately contribute to a more comprehensive understanding of human health, disease susceptibilities, and the pathophysiology of infectious and immune-mediated diseases.

scholarly journals Inherited Ventricular Arrhythmias, the Channelopathies and SCD; Current Knowledge and Future Speculation – Epidemiology and Basic Electrophysiology

2020 ◽  
Author(s):  
Abdullah Abdulrhman Al Abdulgader
Keyword(s):  
Current Knowledge ◽  
Well Being ◽  
Clinical Findings ◽  
Therapeutic Options ◽  
Next Generation ◽  
New Era ◽  
Cardiac Ion Channels ◽  
Scientific Exploration ◽  
Management Plans ◽  
Near Future

This chapter represents advanced scientific exploration in the different disciplines of SCD and channelopathy. Epidemiology of SCD and channelopathy is given special attention. The essence of detailed electrophysiological bases of the different diseases of channelopathies and the diverse cellular pathways mandated detailed discussion that can open the closed doors that we faced to the next generation(s). Special sections have been devoted to spatial as well as temporal heterogeneity of the cardiac action potential. Genetic heterogeneity and allelic heterogeneity are two prominent findings of channelopathies that confirm the fact of the major overlap in the field. The way we present the clinical findings is a true call for the next generation(s) of clinicians and researchers to revolutionize the field in the near future. Detailed management plans based on the up to date basic sciences findings for the different channelopathies give better therapeutic options for the clinicians in the field. Unique to this chapter is the new directions to look for channelopathies beyond the human body. The new understanding of the psychophysiological well-being of HRV and the sympathovagal balance extending to cosmic resonances and its possible effect on cardiac ion channels carries new era of promising preventive, diagnostic and therapeutic options.

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