scholarly journals Recent progress in chemical measuring capabilities in INM as a result of EMRP/EMPIR Programme

2019 ◽  
Author(s):  
Mirella Buzoianu ◽  
Mihail Radu ◽  
George Victor Ionescu
Keyword(s):  
Gas Chromatography ◽  
Best Practice ◽  
Research Work ◽  
Joint Research ◽  
Icp Ms ◽  
Measurement Results ◽  
Mass Fractions ◽  
Plasma Mass Spectrometry ◽  
Inductive Couple Plasma ◽  
Metrology Research

New metrology capabilities in chemical area are of great interest as they underpin the traceability of measurement results reported in environment, health or food sectors. To develop such capabilities a consistent research work is needed. Since 2009, the European Metrology Research Program (EMRP) enabled the National Institute of Metrology (INM) from Romania to join several Joint Research Projects (JRPs) in chemical field. Main outcomes of this helped INM in developing and implementing measurement capabilities in gas chromatography (GC) and inductive couple plasma mass spectrometry (ICP-MS). Accordingly, a brief review of the best practice achieved at INM after participating in ENV08 and SIB09 is described. Further, the European Metrology Programme for Innovation and Research (EMPIR) facilitated expanding the existing metrology capabilities/infrastructure within the frame of two research potential projects (RPOT) in chemical field. Aspects regarding developing ICP-MS technique for measuring mass fractions of elements in natural matrix are presented in the frame of EMPIR RPOT1601. Also, some developments are presented in gas chromatography as a result of participating in the EMPIR RPOT1602.

Using Inductively Coupled Plasma Mass Spectrometry to Assess Essential and Performance-Enhancing Metals in the Urine of Racehorses

2020 ◽  
Vol 44 (5) ◽  
pp. 490-498
Author(s):  
Abdul Khader Karakka Kal ◽  
Zubair Perwad ◽  
Tajudheen K Karatt ◽  
Jahfar Nalakath ◽  
Michael Subhahar
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Performance Enhancement ◽  
Research Work ◽  
High Sensitivity ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
And Performance ◽  
Sport Events

Abstract Recently, an increased tendency to use various metals has been observed in the sports competition fields. Many of these metals and their organic complexes reportedly have good pharmacologic, therapeutic and performance-enhancement uses; they are banned or recommended as controlled medications in competitive sports. The objective of this research was to determine the concentration of pharmacologically relevant metals in urine samples collected from racehorses at various sport events, develop a method and assess the concentrations of above metals using inductively coupled plasma mass spectrometry (ICP-MS). Seven alkali–alkaline earth metals (lithium, sodium, potassium, magnesium, calcium, strontium and barium) and six heavy metals (chromium, cobalt, copper, zinc, arsenic and selenium) were studied in detail. To compare and confirm the concentrations of these metals, the screening was carried out on the basis of region and sex of the animal. ICP-MS provides extremely high sensitivity that enables the determination of the metals at very low concentration from complex biological matrices. From the research, it is clear that irrespective of sex and region the concentration of metal is very high in some samples, might be accidental or intentional doping to improve sporting performances. This research work is of significant importance in setting threshold values for screening metals in race day samples in order to avoid potential harmful effects on athletes and the depth of malpractices, it can bring to sports.

scholarly journals The use of multi-criteria method in the process of threat assessment to the environment

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Elwira Zajusz-Zubek ◽  
Zygmunt Korban
Keyword(s):  
Particulate Matter ◽  
Inductively Coupled Plasma ◽  
Power Plants ◽  
Threat Assessment ◽  
Atmospheric Composition ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Measurement Results ◽  
Plasma Mass Spectrometry ◽  
Carcinogenic Metals

AbstractMeasurements of the content of trace elements, including toxic and carcinogenic metals, in various fractions of particulate matter PM are an important element of environmental monitoring and research involving their impact on human health. The article presents the measurement results of atmospheric composition of suspended dust (PM10), respirable fraction (PM2.5) and submicron particulate matter (PM1) collected with the Dekati PM10 cascade impactor. Samples were collected in the vicinity of four working power plants (from 28 May to 23 September 2014) and four coking plants (from 4 May to 28 August 2015) in Upper Silesia, Poland. The qualitative and quantitative analysis of the solutions: arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), mercury (Hg), manganese (Mn), nickel (Ni), lead (Pb), antimony (Sb) and selenium (Se) obtained for individual fractions was performed by inductively coupled plasma mass spectrometry, using the apparatus ICP-MS. The research results were used to determine a synthetic assessment of the threat to the anthropogenic environment and for the preparation of the ranking of the measured points.

scholarly journals Determination of 18 Trace Elements in 10 Batches of the Tibetan Medicine Qishiwei Zhenzhu Pills by Direct Inductively Coupled Plasma-Mass Spectrometry

2022 ◽  
Vol 2022 ◽  
pp. 1-10
Author(s):  
Ke Fu ◽  
Yinglian Song ◽  
Dewei Zhang ◽  
Min Xu ◽  
Ruixia Wu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Trace Elements ◽  
Inductively Coupled Plasma ◽  
Tibetan Medicine ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Gold Silver ◽  
Mass Fractions ◽  
Plasma Mass Spectrometry

Qishiwei Zhenzhu pills (QSW) was first recorded in the Tibetan medicine classic Si Bu Yi Dian and has been used to treat “Baimai” disease, stroke, paralysis, hemiplegia, cerebral hemorrhage, and other diseases till today. This prescription contains more than 70 medicines including myrobalan, pearl, agate, opal, bezoar, coral, musk, gold, silver, and a mineral mixture Zuotai. As a result, QSW contains a large amount of mercury, copper, lead, and other trace elements. The aim of this study was to determine the 18 trace elements (lithium, beryllium, scandium, vanadium, chromium, manganese, cobalt, nickel, copper, arsenic, strontium, argentum, cadmium, cesium, barium, lead, aurum, and mercury) in 10 batches of QSW produced by 5 pharmaceutical companies (Ganlu Tibetan Medicine Co., Ltd. has 6 different batches) by direct inductively coupled plasma-mass spectrometry (ICP-MS). ICP-MS is a rapid, sensitive, accurate methodology allowing the determination of 18 elements simultaneously. The results showed that each element had an excellent linear relationship in the corresponding mass concentration range. The results showed that the rank order of the elements in QSW was copper > mercury > lead from high to low, with the mass fraction higher than 6000 μg/kg; the mass fractions of argentum, arsenic, manganese, aurum, strontium, barium, chromium, and nickel were in the range of 33–1034 μg/kg; and the mass fractions of vanadium, cobalt, lithium, beryllium, cadmium, scandium, and cesium were lower than 10 μg/kg. The reproducibility from the same manufacturer (Tibet Ganlu Tibetan Medicine Co., Ltd.) was relatively high; however, the element amounts among 5 manufacturers were different, which could affect the efficacy and toxicity of QSW. All in all, ICP-MS can be used as an effective tool for the analysis of trace elements in QSW and standard quality control needs to be enforced across different manufactures.

Single Particle Inductively Coupled Plasma Mass Spectrometry: Investigating Nonlinear Response Observed in Pulse Counting Mode and Extending the Linear Dynamic Range by Compensating for Dead Time Related Count Losses on a Microsecond Timescale

2019 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Inorganic Nanoparticles ◽  
Linear Dynamic Range ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

<p>The article demonstrates the importance of using a suitable approach to compensate for dead time relate count losses (a certain measurement artefact) whenever short, but potentially strong transient signals are to be analysed using inductively coupled plasma mass spectrometry (ICP-MS). Findings strongly support the theory that inadequate time resolution, and therefore insufficient compensation for these count losses, is one of the main reasons for size underestimation observed when analysing inorganic nanoparticles using ICP-MS, a topic still controversially discussed.</p>

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