Synthesis of Cyclic Phosphinates by Microwave-Assisted Ionic Liquid-Promoted Alcoholysis

Synthesis ◽  
2021 ◽  
Author(s):  
Nikoletta Harsági ◽  
Nóra Zsuzsa Kiss ◽  
László Drahos ◽  
György Keglevich
Keyword(s):  
Ionic Liquid ◽  
Crucial Role ◽  
Ethyl Esters ◽  
Alternative Possibility ◽  
Microwave Assisted ◽  
Mw Irradiation

A series of 1-alkoxy-3-methyl- and 3,4-dimethyl-3-phospholene 1-oxides, as well as 1-alkoxy-3-methylphospholane 1-oxides were prepared in good yields by the microwave (MW)-assisted [bmim][PF6]-catalyzed transesterification of the corresponding methyl or ethyl esters. The alcoholyses studied represent another case, where MW irradiation has had a crucial role on the course of the reaction. The method developed is an alternative possibility to other esterifications starting from the corresponding phosphinic chlorides and acids.

scholarly journals MW irradiation and ionic liquids as green tools in hydrolyses and alcoholyses

2020 ◽  
Vol 10 (1) ◽  
pp. 001-010 ◽  
Author(s):  
Nikoletta Harsági ◽  
Betti Szőllősi ◽  
Nóra Zsuzsa Kiss ◽  
György Keglevich
Keyword(s):  
Ionic Liquids ◽  
Alkaline Hydrolysis ◽  
Alkyl Group ◽  
Phosphinic Acid ◽  
Reaction Times ◽  
Alternative Possibility ◽  
First Order ◽  
Pseudo First Order ◽  
Mw Irradiation ◽  
Hydrolysis Of

Abstract The optimized HCl-catalyzed hydrolysis of alkyl diphenylphosphinates is described. The reaction times and pseudo-first-order rate constants suggested the iPr > Me > Et ∼ Pr ∼ Bu order of reactivity in respect of the alkyl group of the phosphinates. The MW-assisted p-toluenesulfonic acid (PTSA)-catalyzed variation means a better alternative possibility due to the shorter reaction times, and the alkaline hydrolysis is another option. The transesterification of alkyl diphenylphosphinates took place only in the presence of suitable ionic liquids, such as butyl-methylimidazolium hexafluorophosphorate ([bmim][PF6]) and butyl-methylimidazolium tetrafluoroborate ([bmim][BF4]). The application of ethyl-methylimidazolium hydrosulfate ([emim][HSO4]) and butyl-methylimidazolium chloride ([bmim][Cl]) was not too efficient, as the formation of the ester was accompanied by the fission of the O–C bond resulting in the formation of Ph2P(O)OH. This surprising transformation may be utilized in the phosphinate → phosphinic acid conversion.

Microwave-Assisted Preparation of Molecularly Imprinted Monolith Combining Imidazolium Ionic Liquid and POSS for Enhanced Extraction of Baicalin-Like Compounds in Scutellaria Baicalensis by means of In-Capillary SPME Followed by on-line LC and off-line LC-MS/MS

2021 ◽  
Author(s):  
Xiaohan Zhang ◽  
Le Gao ◽  
Liying Niu ◽  
Xiaodong Bi
Keyword(s):  
Ionic Liquid ◽  
Molecularly Imprinted Polymers ◽  
Scutellaria Baicalensis ◽  
Synthetic Methods ◽  
Imidazolium Ionic Liquid ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Microwave Assisted ◽  
On Line ◽  
Molecularly Imprinted Monolith

Molecularly imprinted polymers (MIPs) possess target-customized and range-adjustable selectivity, and hence have been attracting increasing efforts to develop new synthetic methods and new forms of applications. By wisely choosing functional...

Ionic liquid-based ultrasonic/microwave-assisted extraction combined with UPLC–MS–MS for the determination of tannins inGalla chinensis

2012 ◽  
Vol 26 (19) ◽  
pp. 1842-1847 ◽  
Author(s):  
Chunxia Lu ◽  
Hongxin Wang ◽  
Wenping Lv ◽  
Chaoyang Ma ◽  
Zaixiang Lou ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Microwave Assisted Extraction ◽  
Microwave Assisted ◽  
Assisted Extraction

scholarly journals Microwave-Assisted Ionic Liquid Catalyzed One-Pot Three-Component Synthesis of 3-{1-[2-(4-Arylthiazol-2-yl)-hydrazono]ethyl}-2H-chromen-2-one

2012 ◽  
Vol 32 (9) ◽  
pp. 1732
Author(s):  
Dongnuan Zhang ◽  
Jitai Li ◽  
Huimin Liu ◽  
Yali Song ◽  
Yingqun Zhang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
One Pot ◽  
Microwave Assisted
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