B. Aerodigestive Neoplasms of the Head and Neck: Parapharyngeal Space Tumors

Background: Parapharyngeal space tumors account for some 0.5% of tumors of the head and neck, most ofthem benign. The most common benign neoplasms are salivary gland neoplasm, paragangliomas and followed byneurogenic tumors. The importance of these tumors lies mainly in two aspects, the difficulty of early diagnosis,due to the lack of symptoms in the initial stages and, on the other hand, the extreme risk of complications inperforming surgery in the parapharyngeal region. Purpose: We present this case to enlighten generalpractitioners and also otorhinolaryngologist about diagnosis and management of parapharyngeal tumor. Case:One clinical case of neuroendocrine tumor in parapharyngeal space on a 37 years old man. Management: Thepatient underwent diagnosis procedure and extirpation of the tumor mass. Conclusion: Parapharyngeal tumor isone of head and neck tumors that has good prognosis, especially if diagnosed early and adequately treated.Keywords: neuroendocrine tumor, parapharyngeal space, benign tumor.ABSTRAKLatar belakang: Tumor parafaring meliputi sekitar 0,5% dari seluruh tumor kepala dan leher, sebagianbesar jinak. Tumor jinak yang paling sering adalah tumor kelenjar liur, paraganglioma dan tumor neurogenik.Tumor parafaring ini penting disebabkan sulit untuk melakukan diagnosis dini karena sedikitnya gejala padatahap awal dan kemungkinan komplikasi yang dapat terjadi pada saat dilakukan tindakan bedah di daerahparafaring. Tujuan: Kasus ini diajukan agar para dokter umum dan spesialis Telinga Hidung Tenggorok dapatmengenali diagnosis dan penatalaksanaan tumor parafaring. Kasus: Dilaporkan satu kasus tumorneuroendokrin parafaring pada laki-laki usia 37 tahun. Penatalaksanaan: Pada pasien ini dilakukan proseduruntuk mendiagnosis tumor dan dilakukan ekstirpasi massa tumor. Kesimpulan: Tumor parafaring merupakansalah satu dari tumor kepala dan leher yang mempunyai prognosis baik terutama bila didiagnosis secara dinidan diterapi secara adekuat.Kata kunci: Tumor neuroendokrin, spatium parafaring, tumor jinak.

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Undifferentiated carcinoma of parapharyngeal space in 8 year old female child: a rare case presentation

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20160961 ◽

2016 ◽

Vol 2 (2) ◽

pp. 88

Author(s):

Ramesh Kadela ◽

Sonia Jindal ◽

Pooja Arya ◽

Niranjan Nagaraj ◽

Deepchand Lal ◽

...

Keyword(s):

Head And Neck ◽

Malignant Tumor ◽

Rare Case ◽

Parapharyngeal Space ◽

Female Child ◽

Undifferentiated Carcinoma ◽

Head And Neck Tumors ◽

Case Presentation ◽

Parapharyngeal Space Tumors ◽

Neck Tumors

Parapharyngeal space tumors represent only 0.5% of all head and neck tumors. Out of which, 80% are benign and 20% are malignant. Tumor must be at least 2 cm in size before bulge or abnormality is palpable. We report a case of 8 year old female child who presented with bulge in right tonsillar region.

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Parapharyngeal Space Tumors

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1059 ◽

2011 ◽

Vol 2 (2) ◽

pp. 95-99 ◽

Cited By ~ 1

Author(s):

Pratima S Khandawala

Keyword(s):

Head And Neck ◽

Head And Neck Neoplasms ◽

Hyoid Bone ◽

Parapharyngeal Space ◽

Ct Scanning ◽

Surgical Excision ◽

Styloid Process ◽

Potential Space ◽

Parapharyngeal Space Tumors ◽

Complete Surgical Excision

ABSTRACT Parapharyngeal space is a potential space in the neck extending from skull base to the greater cornu of hyoid bone. It is divided in prestyloid and poststyloid compartment by the fascia joining styloid process to tensor veli palatini. Tumors of parapharyngeal space are uncommon, comprising of less than 1% of all head and neck neoplasms. CT Scanning and MRI investigations is complimentary and both studies should be performed for evaluation of lesions in this area. Complete surgical excision is the mainstay of treatment.

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Epithelioid haemangioendothelioma in the parapharyngeal space

The Journal of Laryngology & Otology ◽

10.1017/s0022215106000314 ◽

2006 ◽

Vol 120 (6) ◽

pp. 505-507 ◽

Cited By ~ 7

Author(s):

J-C Lee ◽

B-J Lee ◽

S-G Wang ◽

H-W Kim

Keyword(s):

Endothelial Cells ◽

Facial Nerve ◽

Head And Neck ◽

Soft Tissues ◽

Parapharyngeal Space ◽

Malignant Potential ◽

Vascular Neoplasm ◽

Cytoplasmic Vacuolation ◽

Upper And Lower Extremities ◽

Epithelioid Haemangioendothelioma

Epithelioid haemangioendothelioma (EHE) is an uncommon vascular neoplasm which occurs rarely in the head and neck and has an unpredictable clinical behaviour. It is characterized by round or spindle-shaped endothelial cells with cytoplasmic vacuolation. Most often, EHE arises from the soft tissues of the upper and lower extremities, and it has borderline malignant potential. We describe the first reported case of EHE in the parapharyngeal space, which was treated successfully via a transcervical–transparotid approach (following angiography with embolization), without massive intra-operative bleeding or facial nerve damage.

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A comparative study of the endoscopy-assisted transoral approach versus external approaches for the resection of large benign parapharyngeal space tumors

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2016.09.010 ◽

2017 ◽

Vol 123 (2) ◽

pp. 157-162 ◽

Cited By ~ 6

Author(s):

Song Fan ◽

Shi-geng Lin ◽

Han-qing Zhang ◽

Qun-xing Li ◽

Wei-xiong Chen ◽

...

Keyword(s):

Comparative Study ◽

Parapharyngeal Space ◽

Transoral Approach ◽

Parapharyngeal Space Tumors

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Transoral Robotic Surgery for Parapharyngeal Space Tumors

ORL ◽

10.1159/000320596 ◽

2010 ◽

Vol 72 (6) ◽

pp. 332-336 ◽

Cited By ~ 89

Author(s):

Bert W. O’Malley Jr. ◽

Harry Quon ◽

Fernando D. Leonhardt ◽

Ara A. Chalian ◽

Gregory S. Weinstein

Keyword(s):

Robotic Surgery ◽

Parapharyngeal Space ◽

Transoral Robotic Surgery ◽

Parapharyngeal Space Tumors

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Dissection of Parapharyngeal Space in Head and Neck Cancer

Auris Nasus Larynx ◽

10.1016/s0385-8146(85)80030-4 ◽

1985 ◽

Vol 12 ◽

pp. S56-S60 ◽

Cited By ~ 5

Author(s):

Ken Omura ◽

Fumiyuki Shimada ◽

Sanzo Takemiya

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Parapharyngeal Space

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Clinical Study of Parapharyngeal Space Tumors

Nippon Jibiinkoka Gakkai Kaiho ◽

10.3950/jibiinkoka.107.1053 ◽

2004 ◽

Vol 107 (12) ◽

pp. 1053-1059 ◽

Cited By ~ 5

Author(s):

Akinori Kashio ◽

Kazunari Nakao ◽

Masato Machiki ◽

Takaharu Nito ◽

Masashi Sugasawa

Keyword(s):

Clinical Study ◽

Parapharyngeal Space ◽

Parapharyngeal Space Tumors

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A Site of Origin Histopathological Study on Parapharyngeal Space Tumors. A Review of 76 Cases.

Nippon Jibiinkoka Gakkai Kaiho ◽

10.3950/jibiinkoka.116.27 ◽

2013 ◽

Vol 116 (1) ◽

pp. 27-30 ◽

Cited By ~ 3

Author(s):

Isaku Okamoto ◽

Shinetsu Kamata ◽

Kouki Miura ◽

Yuichirou Tada ◽

Tatsuo masubuchi ◽

...

Keyword(s):

Parapharyngeal Space ◽

Histopathological Study ◽

Parapharyngeal Space Tumors ◽

A Site

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A comparative study of parapharyngeal space tumors over a 7 year period experience in tertiary care hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20182958 ◽

2018 ◽

Vol 4 (5) ◽

pp. 1167

Author(s):

Athiyaman K. ◽

Gowri Shankar M. ◽

Suresh V. ◽

Natarajan S. ◽

Malarvizhi R.

Keyword(s):

Parapharyngeal Space ◽

Malignant Tumors ◽

Tertiary Care ◽

Direct Access ◽

Vascular Lesions ◽

Care Hospital ◽

Neurogenic Tumors ◽

Parapharyngeal Space Tumors ◽

First Choice ◽

Cervical Approach

Background: Tumors of the parapharyngeal space (PPS) are rare, accounting for 0.5–1.5% of all head and neck tumors. The anatomy of the PPS is responsible for a wide variety of tumors arising from the PPS. Our series of 10 PPS tumors provides an overview of the clinical course and management of PPS tumors.Methods: This retrospective study included clinical data from patients treated for PPS tumors from 2011 to 2018 at the Stanley medical college hospital, Chennai. Results: After careful analysis of the outcome of the study, we have found out that there was no local recurrence in any patient during the follow-up period. Though few approaches are advised in the literature, In our study transoral approach may be advocated as the first choice for excision of parapharyngeal space tumors, except for malignant tumors and neurogenic tumor. Trans cervical approach is used for malignant and neurogenic tumors, considering its advantages of providing direct access to the neoplasm, adequate control of neurovascular structures from the neck.Conclusions: In our study, middle aged male population was most commonly affected. Pleomorphic adenoma is the most common PPS tumor; prestyloid compartment is mostly affected by these tumors. As per the previous studies, trans cervical approach is first choice for excision of parapharyngeal space tumors. In our study, trans oral approach is also a suitable, safe approach for pre styloid non vascular lesions and trancervical approach can be reserved for postsyloid and malignant lesions.

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