Neuroendocrine tumor of parapharyngeal space

Background: Parapharyngeal space tumors account for some 0.5% of tumors of the head and neck, most ofthem benign. The most common benign neoplasms are salivary gland neoplasm, paragangliomas and followed byneurogenic tumors. The importance of these tumors lies mainly in two aspects, the difficulty of early diagnosis,due to the lack of symptoms in the initial stages and, on the other hand, the extreme risk of complications inperforming surgery in the parapharyngeal region. Purpose: We present this case to enlighten generalpractitioners and also otorhinolaryngologist about diagnosis and management of parapharyngeal tumor. Case:One clinical case of neuroendocrine tumor in parapharyngeal space on a 37 years old man. Management: Thepatient underwent diagnosis procedure and extirpation of the tumor mass. Conclusion: Parapharyngeal tumor isone of head and neck tumors that has good prognosis, especially if diagnosed early and adequately treated.Keywords: neuroendocrine tumor, parapharyngeal space, benign tumor.ABSTRAKLatar belakang: Tumor parafaring meliputi sekitar 0,5% dari seluruh tumor kepala dan leher, sebagianbesar jinak. Tumor jinak yang paling sering adalah tumor kelenjar liur, paraganglioma dan tumor neurogenik.Tumor parafaring ini penting disebabkan sulit untuk melakukan diagnosis dini karena sedikitnya gejala padatahap awal dan kemungkinan komplikasi yang dapat terjadi pada saat dilakukan tindakan bedah di daerahparafaring. Tujuan: Kasus ini diajukan agar para dokter umum dan spesialis Telinga Hidung Tenggorok dapatmengenali diagnosis dan penatalaksanaan tumor parafaring. Kasus: Dilaporkan satu kasus tumorneuroendokrin parafaring pada laki-laki usia 37 tahun. Penatalaksanaan: Pada pasien ini dilakukan proseduruntuk mendiagnosis tumor dan dilakukan ekstirpasi massa tumor. Kesimpulan: Tumor parafaring merupakansalah satu dari tumor kepala dan leher yang mempunyai prognosis baik terutama bila didiagnosis secara dinidan diterapi secara adekuat.Kata kunci: Tumor neuroendokrin, spatium parafaring, tumor jinak.

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Undifferentiated carcinoma of parapharyngeal space in 8 year old female child: a rare case presentation

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20160961 ◽

2016 ◽

Vol 2 (2) ◽

pp. 88

Author(s):

Ramesh Kadela ◽

Sonia Jindal ◽

Pooja Arya ◽

Niranjan Nagaraj ◽

Deepchand Lal ◽

...

Keyword(s):

Head And Neck ◽

Malignant Tumor ◽

Rare Case ◽

Parapharyngeal Space ◽

Female Child ◽

Undifferentiated Carcinoma ◽

Head And Neck Tumors ◽

Case Presentation ◽

Parapharyngeal Space Tumors ◽

Neck Tumors

Parapharyngeal space tumors represent only 0.5% of all head and neck tumors. Out of which, 80% are benign and 20% are malignant. Tumor must be at least 2 cm in size before bulge or abnormality is palpable. We report a case of 8 year old female child who presented with bulge in right tonsillar region.

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Parapharyngeal Schawannnoma. Case Report

Revista de la Facultad de Medicina Humana ◽

10.25176/rfmh.v21i4.3985 ◽

2021 ◽

Vol 21 (4) ◽

pp. 874-880

Author(s):

Enrique Moyano Navarro ◽

Manuel Inostroza Fernández ◽

Pedro P. Sotelo Jiménez ◽

Ethel Vargas Carrillo ◽

Alan La Torre Zúñiga ◽

...

Keyword(s):

Case Report ◽

Surgical Treatment ◽

Head And Neck ◽

Female Patient ◽

Parapharyngeal Space ◽

Incisional Biopsy ◽

Neck Tumors ◽

Low Incidence ◽

Parapharyngeal Tumor ◽

Slow Growing

Parapharyngeal tumor lesions present a low incidence, representing between 0,5 and 0,8% of all head and neck tumors. Approximately 80% show benign behavior. The uniqueness of these lesions derives from their complex anatomical situation and the symptoms with which they usually appear, being in most cases nonspecific and almost always derived from the compressive effect produced by the lesion on the oropharynx and the oropharynx. Schwannomas of the parapharyngeal space are very rare tumors that originate from the sheath of schawnn, generally slow growing, and are usually asymptomatic. Treatment is surgical, often complex due to the anatomical location.The case of a 42-year-old female patient with a diagnosis of Schwannoma in the left parapharyngeal region, demonstrated by incisional biopsy, is presented; undergoing surgical treatment, which was carried out without complications.

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B. Aerodigestive Neoplasms of the Head and Neck: Parapharyngeal Space Tumors

Head and Neck Surgery ◽

10.1055/b-0034-80050 ◽

2013 ◽

Keyword(s):

Head And Neck ◽

Parapharyngeal Space ◽

Parapharyngeal Space Tumors

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Risk Factors of Ischemic Stroke in Children with Head and Neck Tumors: A Clinical Case Description with a Literature Review

American Journal of Pediatrics ◽

10.11648/j.ajp.20210703.24 ◽

2021 ◽

Vol 7 (3) ◽

pp. 163

Author(s):

Anastasia D. Rodina ◽

Vladimir Sh. Vanesyan ◽

Tatiana V. Gorbunova ◽

Natalia V. Ivanova ◽

Vladimir G. Polyakov

Keyword(s):

Risk Factors ◽

Ischemic Stroke ◽

Literature Review ◽

Head And Neck ◽

Clinical Case ◽

Head And Neck Tumors ◽

Case Description ◽

Neck Tumors

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Rhabdomyoma of the parapharyngeal space

ACTUALIDAD MEDICA ◽

10.15568/am.2021.813.cc05 ◽

2021 ◽

Vol 106 (106(813)) ◽

pp. 215-217

Author(s):

C. Acosta-Vásquez ◽

L. Uceda-Carrascosa ◽

F. Leiva-Cepas ◽

L. Rodríguez-Pérez

Keyword(s):

Head And Neck ◽

Clinical Case ◽

Benign Tumor ◽

Parapharyngeal Space ◽

Asymptomatic Patient ◽

Histological Study ◽

Mesenchymal Tumor ◽

Skeletal Tissue ◽

Rare Benign Tumor ◽

Ct And Mri

Rhabdomyoma is a benign tumor that comes from skeletal tissue, it is classified as cardiac and extracardiac according to the location. Extracardiac rhabdomyomas most frequently originate in the head and neck at the larynx and pharynx, being the parapharyngeal space an exceptional location. We present the clinical case of an 86-year-old man asymptomatic patient with a laterocervical mass with years of evolution, that has increased its size progressively, with dysphagia and dyspnea on exertion in the last years. CT and MRI were requested, which provided dimensions, location at the parapharyngeal space, as well as signs of benignity. The FNA results indicated that it was a mesenchymal tumor. After cervicotomy and histological study, the diagnosis of parapharyngeal space rhabdomyoma was confirmed. We conducted a bibliographic review of this extremely rare benign tumor at the head and neck level.

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Primary Pleomorphic Adenoma of Minor Salivary Gland in the Parapharyngeal Space

Otorhinolaryngology Clinics - An International Journal ◽

10.5005/jp-journals-10003-1249 ◽

2016 ◽

Vol 8 (3) ◽

pp. 125-127

Author(s):

Ankita Joshi ◽

Chinmaya Sundar Ray

Keyword(s):

Salivary Gland ◽

Head And Neck ◽

Pleomorphic Adenoma ◽

Parapharyngeal Space ◽

Minor Salivary Gland ◽

Rare Occurrence ◽

Normal Tissues ◽

Neck Tumors ◽

Minor Salivary Gland Tumors ◽

High Index Of Suspicion

ABSTRACT Parapharyngeal space (PPS) lesions account for only 0.5% head and neck tumors and the majority of the minor salivary gland tumors are malignant. We report a case of pleomorphic adenoma of minor salivary gland in PPS as this is of a very rare occurrence. High index of suspicion and an adequate clearance of the tumor with a cuff of surrounding dispensable normal tissues are the key to successful treatment of such tumors. How to cite this article Ray CS, Joshi A. Primary Pleomorphic Adenoma of Minor Salivary Gland in the Parapharyngeal Space. Int J Otorhinolaryngol Clin 2016;8(3):125-127.

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Surgical Approaches to Parapharyngeal Space Tumors: An Example and Review of the Literature

Case Reports in Surgery ◽

10.1155/2021/3536145 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Souheil Jbali ◽

Amira Khaldi ◽

Slim Touati ◽

Said Gritli

Keyword(s):

Pleomorphic Adenoma ◽

Tumor Volume ◽

Parapharyngeal Space ◽

Correct Diagnosis ◽

Surgical Approaches ◽

Parapharyngeal Space Tumors ◽

Neck Tumors ◽

Pleomorphic Adenomas ◽

The Common ◽

Magnetic Resonance Imaging Mri

Parapharyngeal space tumors (PPS) are rare. They represent less than 1% of all head and neck tumors. They are of various histologies. Pleomorphic adenomas originating from the parotid (prestylian parapharyngeal space) are the most frequent. We report the case of a 50-year-old patient treated for a pleomorphic adenoma (PA) of PPS. His initial complaints were apnea and dysphagia. The correct diagnosis was preoperatively suspected by magnetic resonance imaging (MRI). The surgery was carried out using two approaches: transoral and cervical transparotid approaches. Definitive histology was consistent with encapsulated pleomorphic adenoma. In the present work, we reviewed clinical, radiological, and histological features of parapharyngeal space tumors. We tried to summarize the common surgical approaches. The chosen approach is, in fact, scheduled taking into account several parameters including tumor volume and purpose of the surgery.

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Transoral Excision of Parapharyngeal Tumors

Ear Nose & Throat Journal ◽

10.1177/0145561320923171 ◽

2020 ◽

pp. 014556132092317 ◽

Cited By ~ 1

Author(s):

Wilson P. Lao ◽

Peter S. Han ◽

Nathan H. Lee ◽

Jason E. Gilde ◽

Jared C. Inman

Keyword(s):

Parapharyngeal Space ◽

Transoral Approach ◽

Direct Access ◽

Nerve Injuries ◽

Blunt Dissection ◽

Tumor Capsule ◽

Parapharyngeal Space Tumors ◽

Parapharyngeal Tumors ◽

Tumor Delivery ◽

Parapharyngeal Tumor

Objectives: The transoral approach for parapharyngeal space tumors has been criticized due to its restrictive exposure and increased rate of vascular and nerve injuries. However, for certain tumors—namely those that are prestyloid, benign, and well-encapsulated—the transoral approach reduces overall morbidity while providing direct access. Transoral surgeons can rely on this approach for select tumors seen clearly on intraoral examination in the bulging lateral pharynx. In this article and with a supplemental operative technique video, we demonstrate our transoral approach in these select patients. Methods: We reviewed our 26 cases using this approach and chose a representative case of a 50-year-old man who presented with a large, prestyloid, encapsulated parapharyngeal mass affecting his voice and swallowing. A transoral approach to the parapharyngeal tumor is illustrated. Results: A vertical curvilinear incision is completed from the hamulus to below the inferior extent of the tumor. Blunt dissection of the tumor capsule proceeds inferiorly. Controlled violation of the tumor capsule can aid in visualization. After tumor delivery, the wound is irrigated and closed. Conclusions: In our experience, the transoral approach is an effective method to access well-encapsulated, prestyloid parapharyngeal space tumors. Patient selection is important when considering a transoral approach.

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Parapharyngeal Space Tumors

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1059 ◽

2011 ◽

Vol 2 (2) ◽

pp. 95-99 ◽

Cited By ~ 1

Author(s):

Pratima S Khandawala

Keyword(s):

Head And Neck ◽

Head And Neck Neoplasms ◽

Hyoid Bone ◽

Parapharyngeal Space ◽

Ct Scanning ◽

Surgical Excision ◽

Styloid Process ◽

Potential Space ◽

Parapharyngeal Space Tumors ◽

Complete Surgical Excision

ABSTRACT Parapharyngeal space is a potential space in the neck extending from skull base to the greater cornu of hyoid bone. It is divided in prestyloid and poststyloid compartment by the fascia joining styloid process to tensor veli palatini. Tumors of parapharyngeal space are uncommon, comprising of less than 1% of all head and neck neoplasms. CT Scanning and MRI investigations is complimentary and both studies should be performed for evaluation of lesions in this area. Complete surgical excision is the mainstay of treatment.

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Parapharyngeal space schwannomas: our experience and review of literature

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20171198 ◽

2017 ◽

Vol 3 (2) ◽

pp. 385 ◽

Cited By ~ 1

Author(s):

Inderdeep Singh ◽

Vikas Gupta ◽

Sunil Goyal ◽

Manoj Kumar ◽

Anubhav Singh

Keyword(s):

Head And Neck ◽

Cranial Nerve ◽

Parapharyngeal Space ◽

Study Data ◽

Review Of Literature ◽

Neck Tumors ◽

Cranial Nerve Palsies ◽

Benign Nature ◽

Lateral Neck Swelling ◽

Rare Group

Background: Tumors of the parapharyngeal space are a rare group of head & neck tumors. Due to their indolent nature they present late with either cranial nerve palsy or lateral neck swelling. The aim of the study was i) to determine the incidence of parapharyngeal space schwannoma among defence personnel’s and their dependents presenting to ENT OPD and ii) to study the clinical presentation, management and outcomes of such lesion.Methods: The study is a retrospective observational study. All new patients referred to ENT OPD at our center were included in the study. Data was collected from our OPD records over two years between Jan 2015 and Dec 2016. Results: It was found that the incidence rate of parapharyngeal space schwannoma was 0.034% out of all fresh cases reporting to ENT OPD and 0.47% out of all fresh diagnosed cases of head and neck tumours at our centre. Out of the total 5 cases of parapharyngeal space schwannomas, 2 patients had vagal schwannomas and one each had hypoglossal nerve schwannoma, spinal accessory nerve schwannoma and sympathetic chain schwannoma.Conclusions: Schwannomas of the parapharyngeal region can be very extensive and may require to be removed in a staged procedure involving the head & neck and neurosurgeons.It is important to distinguish these tumors from other head and neck malignancies by detail clinical and radiological examinations. Despite the benign nature of the disease, the surgery can be morbid with cranial nerve palsies in extensive tumors.

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