The central role of chromenols in the biomimetic synthesis of structurally diverse natural product scaffolds

M Cadelis; D Barker; BR Copp

doi:10.1055/s-0032-1320252

Beyond peptide bond formation: the versatile role of condensation domains in natural product biosynthesis

Natural Product Reports ◽

10.1039/d0np00098a ◽

2021 ◽

Author(s):

Sofie Dekimpe ◽

Joleen Masschelein

Keyword(s):

Natural Product ◽

Bond Formation ◽

Peptide Bond ◽

Chemical Diversity ◽

Peptide Bond Formation ◽

Natural Product Biosynthesis

Condensation domains perform highly diverse functions during natural product biosynthesis and are capable of generating remarkable chemical diversity.

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The role of 1,3-dithianes in natural product synthesis

Tetrahedron ◽

10.1016/s0040-4020(03)00955-4 ◽

2003 ◽

Vol 59 (33) ◽

pp. 6147-6212 ◽

Cited By ~ 180

Author(s):

Miguel Yus ◽

Carmen Nájera ◽

Francisco Foubelo

Keyword(s):

Natural Product ◽

Natural Product Synthesis

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ChemInform Abstract: Biomimetic Synthesis of ent-(-)-Azonazine and Stereoochemical Reassignment of Natural Product.

ChemInform ◽

10.1002/chin.201405200 ◽

2014 ◽

Vol 45 (5) ◽

pp. no-no

Author(s):

Ji-Chen Zhao ◽

Shun-Ming Yu ◽

Yun Liu ◽

Zhu-Jun Yao

Keyword(s):

Natural Product ◽

Biomimetic Synthesis

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Role of the Organic Matrix in the Biopolymer-Mediated Synthesis of Platelike YBCO

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.699.268 ◽

2013 ◽

Vol 699 ◽

pp. 268-272 ◽

Cited By ~ 2

Author(s):

Zi Li Zhang ◽

Stuart C. Wimbush ◽

Ahmed Kursumovic ◽

Hong Li Suo ◽

Judith L. MacManus Driscoll

Keyword(s):

Organic Matrix ◽

Molecular Structures ◽

Biomimetic Synthesis ◽

Synthesis Process ◽

Final Size ◽

Whole Process ◽

Structural And Electrical Properties ◽

Organic Matrices ◽

Superconducting Ceramic

The biomimetic method of achieving dense platelike grain growth of the high temperature superconducting ceramic YBa2Cu3O7 (YBCO) has been studied. By using various organic matrices (dextran and chitosan) having different molecular structures, the final size and arrangement of the platelike YBCO grains exhibit significant differences, possible reasons for which are discussed. The different organic matrices used also indirectly affect the superconducting properties of the YBCO formed. By elucidating the role of the organic matrix in the biomimetic synthesis process in this way, the whole process could be controlled more precisely, leading to structural and electrical properties of the final product more desireable for specific applications.

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Biomimetic synthesis of superparamagnetic iron oxide particles in proteins

Journal of Materials Research ◽

10.1557/jmr.2003.0180 ◽

2003 ◽

Vol 18 (6) ◽

pp. 1309-1313 ◽

Cited By ~ 21

Author(s):

Arvind Sinha ◽

Suprabha Nayar ◽

G. V. S. Murthy ◽

P. A. Joy ◽

V. Rao ◽

...

Keyword(s):

Iron Oxide ◽

Quaternary Structure ◽

Inorganic Ions ◽

Superparamagnetic Iron Oxide ◽

Egg White ◽

Biomimetic Synthesis ◽

Iron Oxide Particles ◽

Superparamagnetic Iron Oxide Particles ◽

Oxide Particles

Matrix-mediated in situ synthesis of monodispersed magnetite and maghemite nanoparticles (2–16 nm) was carried out using the cavities present in gels of globular proteins such as egg white and bovine serum albumin. Under stringent conditions, spatial-charge-distribution-assisted molecular recognition of proteins for inorganic ions led to the site- and polymorph-specific synthesis of superparamagnetic iron oxide particles. A transformation from magnetite to maghemite as a nucleating phase could be observed by partially denaturing the egg white protein, signifying the delicate role of quaternary structure of proteins under different reaction conditions, in determining the size and shape of the polymorph.

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