Ultrasound guided interventions in rotator cuff calcific tendonitis

Author(s):  
PS Zoumpoulis ◽  
PE Zoumpoulis ◽  
I Mastorakou ◽  
K Pahou ◽  
E Panteleakou ◽  
...  
2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1762.1-1763
Author(s):  
C. Darrieutort-Laffite ◽  
P. Arnolfo ◽  
E. Correia ◽  
F. Blanchard ◽  
B. Le Goff

Background:Calcific tendonitis of the rotator cuff is a frequent cause of chronic shoulder pain. It is due to apatite deposits within the tendons. Little data are currently available about proteins associated to crystals within deposits.Objectives:The aim of the study was to quantify 6 proteins in calcific powders obtained from patients who have undergone an ultrasound-guided percutaneous lavage (UGPL) of their calcification and to look for correlations between their concentration and patient characteristics.Methods:Calcific powders were obtained from patients included in the CALCECHO trial whose main objective was to compare post-procedure pain between two groups: methylprednisolone or placebo injected at the end of the lavage [1]. Based on preliminary proteomic data and literature data, the following proteins have been selected and quantified by ELISA: Pigment-epithelium Derived Factor (PEDF), Osteopontin (OPN), Periostin (POSTN), Activin A (ACT A), Osteoprotegerin (OPG) and Bone Morphogenic Protein-2 (BMP-2). The level of each protein was expressed in µg per pg of the total proteins present in the sample. These proteins have been selected for their link to the mineralization. Correlations between the level of each protein and radiographic and ultrasound appearance of the calcific deposits were sought. We also looked for correlations between level of each protein and duration of pain or response to UGPL (Mann-Whitney test).Results:Sixty-six samples were studied: mean age was 48.9 (+/- 9.7) and 68% were female. Mean duration of shoulder pain was 30 months with a mean VAS pain of 68/100 (+/-14). Mean calcification size was 1.8 cm. Results of ELISA were as follows: mean level of PEDF at 1097 pg/µg, mean level of OPG at 135 pg/µg, mean level of POSTN at 6.9 pg/µg, mean level of ACT A at 19.6 pg/µg and mean level of OPN at 49.6 pg/µg although BMP-2 was undetectable. There was no correlation between level of proteins and the size of the calcification or the duration of pain. There was no difference in protein levels between type A and type B calcifications on radiography (classification of the French Society for Arthroscopy). In contrast, levels of POSTN and OPN were significantly higher in nodular calcifications compared to the homogenous (p=0.003 and p=0.01 respectively) or fragmented types (p=0.03 and p=0.04 respectively). Furthermore, calcifications without acoustic shadowing were enriched in POSTN compared to those with (p=0.04). Finally, the periostin level was significantly higher in calcifications that have responded well to UGPL (p=0.02).Conclusion:In this cohort of patients treated by UGPL, we observed higher levels of POSTN and OPN in the less dense calcifications and POSTN enrichment appeared to be associated with a better response to UGPL. Considering these data, further studies will be necessary to better understand the role of this protein in calcific tendonitis.References:[1]Darrieutort-Laffite C, Varin S, Coiffier G, Albert JD, Planche L, Maugars Y, Cormier G, Le Goff B. Are Corticosteroid Injections Needed After Needling and Lavage of Calcific Tendinitis: A Randomized, Double-Blind, Non-Inferiority Trial. Ann Rheum Dis. 2019 Jun;78(6):837-843.Disclosure of Interests:None declared


2021 ◽  
Vol 9 (7_suppl4) ◽  
pp. 2325967121S0021
Author(s):  
Mauricio Drummond ◽  
Caroline Ayinon ◽  
Albert Lin ◽  
Robin Dunn

Objectives: Calcific tendinitis of the shoulder is a painful condition characterized by the presence of calcium deposits within the tendons of the rotator cuff (RTC) that accounts for up to 7% of cases of shoulder pain1. The most common conservative treatments typically include physical therapy (PT), corticosteroid injection (CSI), or ultrasound-guided aspiration (USA). When conservative management fails, the patient may require arthroscopic surgery to remove the calcium with concomitant rotator cuff repair. The purpose of this study was to characterize the failure rates, defined as the need for surgery, of each of these three methods of conservative treatment, as well as to compare post-operative improvement in patient-reported outcomes (PROs) – including subjective shoulder values (SSV) and visual analog scale (VAS) pain scores – based on the type of pre-operative conservative intervention provided. A secondary aim was to compare post-operative range of motion (ROM) outcomes between groups that failed conservative management. We hypothesized that all preoperative conservative treatments would have equivalent success rates, PROs, and ROM. Bosworth B. Calcium deposits in the shoulder and subacromial bursitis: a survey of 12122 shoulders. JAMA. 1941;116(22):2477-2489. Methods: A retrospective review of all patients who were diagnosed with calcific tendinitis at our institution treated among 3 fellowship trained orthopedic surgeons between 2009 and 2019 was performed. VAS, SSV, and ROM in forward flexion (FF) and external rotation (ER) was abstracted from the medical records. Scores were recorded at the initial presentation as well as final post-operative follow-up visit for those who underwent surgery. The conservative treatment method utilized by each patient was recorded and included PT, CSI, or USA. Failure of conservative management was defined as eventual progression to surgical intervention. Statistical analysis included chi-square, independent t test and ANOVA. Descriptive statistics were used to report data. A p<0.05 was considered to be statistically significant. Results: 239 patients diagnosed with calcific tendinitis were identified in the study period with mean age of 54 years and follow up of at least 6 months. In all, 206 (86.2%) patients underwent a method of conservative treatment. Of these patients, 71/239 (29.7%) underwent PT, 67/239 (28%) attempted CSI, and 68/239 (28.5%) underwent USA. The overall failure rate across all treatment groups was 29.1%, with injections yielding the highest success rate of 54/67 (80.6%). Physical therapy saw the highest failure rate, with 26/71 (36.7%) proceeding to surgical intervention. Patients undergoing physical therapy were statistically more likely to require surgery compared to those undergoing corticosteroid injection (RR 1.88, p= 0.024). Of all 93 patients who underwent surgery, VAS, SSV, ROM improved significantly in all groups. On average, VAS decreased by 4.02 points (6.3 to 2.3), SSV increased by 33 points (51 to 84), FF improved by 13.8º, and ER improved 8.4º between the pre- and post-operative visits (p<0.05). The 33 patients who did not attempt a conservative pre-operative treatment demonstrated the largest post-operative improvement in VAS (-6.00), which was significantly greater than those who previously attempted PT (-3.33, p<0.05). There was a trend towards greater improvement in SSV in the pre-operative PT group (45 to 81) compared to others, but this did not reach statistical significance (p=0.47). Range of motion was not significantly affected by the method of pre-operative conservative intervention. Conclusions: Conservative treatment in the form of physical therapy, corticosteroid injection, and ultrasound-guided aspiration is largely successful in managing calcific tendinitis of the shoulder. Of these, PT demonstrated the highest rate of failure in terms of requiring surgical management. PRO improvement varied among the conservative modalities used, however patients who did not attempt conservative management experienced the greatest improvements following surgery. If surgery is necessary following failed conservative treatment, excellent outcomes can be expected with significant improvements in ROM and PROs. This information should be considered by the surgeon when deciding whether to recommend conservative treatment for the management of calcific tendinitis, as well as which specific method to employ.


2001 ◽  
Vol 27 (6) ◽  
pp. 735-743 ◽  
Author(s):  
Hong-Jen Chiou ◽  
Yi-Hong Chou ◽  
Jinn-Jer Wu ◽  
Tung-Fu Huang ◽  
Hsiao-Li Ma ◽  
...  

2017 ◽  
Vol 7 ◽  
pp. 32 ◽  
Author(s):  
Vetrivel Chezian Sengodan ◽  
Sajith Kurian ◽  
Raghupathy Ramasamy

Background: The treatment of symptomatic partial rotator cuff tear has presented substantial challenge to orthopaedic surgeons as it can vary from conservative to surgical repair. Researches have established the influence of platelet rich plasma in healing damaged tissue. Currently very few data are available regarding the evidence of clinical and radiological outcome of partial rotator cuff tear treated with ultrasound guided platelet rich plasma injection in English literature. Materials and Methods: 20 patients with symptomatic partial rotator cuff tears were treated with ultrasound guided platelet rich plasma injection. Before and after the injection of platelet rich plasma scoring was done with visual analogue score, Constant shoulder score, and UCLA shoulder score at 8 weeks and third month. A review ultrasound was performed 8 weeks after platelet rich plasma injection to assess the rotator cuff status. Results: Our study showed statistically significant improvements in 17 patients in VAS pain score, constant shoulder score and UCLA shoulder score. No significant changes in ROM were noted when matched to the contra-lateral side (P < 0.001) at the 3 month follow-up. The study also showed good healing on radiological evaluation with ultrasonogram 8 weeks after platelet rich plasma injection. Conclusion: Ultrasound guided platelet rich plasma injection for partial rotator cuff tears is an effective procedure that leads to significant decrease in pain, improvement in shoulder functions, much cost-effective and less problematic compared to a surgical treatment.


2019 ◽  
Vol 04 (02) ◽  
pp. 220 ◽  
Author(s):  
F. Del Castillo-González ◽  
J.J. Ramos-Álvarez ◽  
G. Rodríguez-Fabián ◽  
J. González-Pérez ◽  
J. Calderón-Montero

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Domenico Albano ◽  
Angelo Gambino ◽  
Carmelo Messina ◽  
Vito Chianca ◽  
Salvatore Gitto ◽  
...  

Purpose. To assess patients’ experience of ultrasound-guided percutaneous irrigation of rotator cuff calcific tendinopathy (US-PICT). Methods. Ninety-one patients (58 females; mean age: 50.5±8.3 years) treated by US-PICT (local anesthesia, single-needle lavage, and intrabursal steroid injection) answered to a list of questions regarding their experience of the procedure before treatment, immediately after treatment, and three months later. The Borg CR10 scale was used to evaluate perceived pain, discomfort during anesthetic injection, and anxiety. The Wilcoxon, Spearman’s rho, linear regression, and chi-square statistics were used. Results. 81/91 patients complained mild discomfort during the injection of anesthetics (2, 1-2). Pain scores during US-PICT were very low (0, 0-1), with 70% patients having not experienced pain. After treatment, we found a significant reduction of pain (before: 8, 7-8; 3-month: 3, 1-6; p<.001) and anxiety (before: 5, 2-7; during treatment: 2, 1-7; p=0.010), with high overall satisfaction (immediately after: 10, 9-10; 3-month: 9, 7-10) and confidence in the possibility of recovery (immediately after: 9, 8-10; 3-month: 10, 8-10), respectively. Treatments performed before US-PICT were not statistically associated with pain relief (p=0.389) and clinical improvement (p=0.937). We found a correlation between satisfaction immediately postprocedure and confidence in the possibility of recovery (p=0.002) and between satisfaction three months after treatment and clinical improvement (p<0.001) and patients’ reminds about the description of the procedure (p=0.005) and of the potential complications (p=0.035). Conclusions. US-PICT is a mildly painful, comfortable, and well-tolerated procedure, regardless of any previous treatments. Patients’ satisfaction is correlated with clinical benefit and full explanation of the procedure and its complications.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M A Nassef ◽  
A E Allam ◽  
H M N Mohammed

Abstract Background shoulder pain is the third most common musculoskeletal complaint. And rotator cuff muscles tendinopathy is one of the most common causes for shoulder pain. Aim of the Work to evaluate the effectiveness of the percutaneous ultrasound guided PRP injection in improving or treating chronic Rotator Cuff muscles tendinopathy. Patients and Methods this study was conducted on 33 patients presented to Police Hospital Nasr City and diagnosed as cases of rotator cuff tendinopathy for more than 6 months and not responding to NSAIDs. Results there is high significant improvement of the ultrasound findings and clinical manifestations of patients as regard pain, range of motion and power comparing to the base line start. According to this study, PRP was found to be more effective on the long term then short term “comparing results after one and five month”. Conclusion ultrasound guided PRP injection is a safe and an effective treatment modality for rotator cuff tendinopathy as evidenced by decreased pain and improved range of motion across the shoulder joint after the application and follow up of the PRP.


2020 ◽  
Vol 20 ◽  
pp. 195-197
Author(s):  
Luca Saba ◽  
Massimo De Filippo ◽  
Francesco Saba ◽  
Federica Fellini ◽  
Pierre Yves Marcy ◽  
...  

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