Higher 24-h urinary free cortisone, but not cortisol is associated with impaired cortical bone status at the proximal radius in healthy children

2014 ◽  
Vol 122 (03) ◽  
Author(s):  
L Shi ◽  
A Sánchez-Guijo ◽  
MF Hartmann ◽  
E Schönau ◽  
SA Wudy ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Healthy Children ◽  
Bone Status ◽  
Proximal Radius

scholarly journals Adrenarche and Bone Modeling and Remodeling at the Proximal Radius: Weak Androgens Make Stronger Cortical Bone in Healthy Children

2003 ◽  
Vol 18 (8) ◽  
pp. 1539-1546 ◽  
Author(s):  
Thomas Remer ◽  
Kai R Boye ◽  
Michaela Hartmann ◽  
Christina M Neu ◽  
Eckhard Schoenau ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Bone Modeling ◽  
Healthy Children ◽  
Proximal Radius ◽  
Bone Modeling And Remodeling

scholarly journals Pentosidine Is Associated With Cortical Bone Geometry and Insulin Resistance in Otherwise Healthy Children

2019 ◽  
Vol 34 (8) ◽  
pp. 1446-1450
Author(s):  
Joseph M Kindler ◽  
Emma M Laing ◽  
Weixi Liu ◽  
Joel A Dain ◽  
Richard D Lewis
Keyword(s):  
Insulin Resistance ◽  
Cortical Bone ◽  
Bone Geometry ◽  
Healthy Children ◽  
Cortical Bone Geometry

Higher Glucocorticoid Secretion in the Physiological Range Is Associated With Lower Bone Strength at the Proximal Radius in Healthy Children: Importance of Protein Intake Adjustment

2015 ◽  
Vol 30 (2) ◽  
pp. 240-248 ◽  
Author(s):  
Lijie Shi ◽  
Alberto Sánchez-Guijo ◽  
Michaela F Hartmann ◽  
Eckhard Schönau ◽  
Jonas Esche ◽  
...  
Keyword(s):  
Bone Strength ◽  
Protein Intake ◽  
Healthy Children ◽  
Proximal Radius ◽  
Physiological Range

scholarly journals Irisin and Bone: From Preclinical Studies to the Evaluation of Its Circulating Levels in Different Populations of Human Subjects

Cells ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 451 ◽  
Author(s):  
Graziana Colaianni ◽  
Lorenzo Sanesi ◽  
Giuseppina Storlino ◽  
Giacomina Brunetti ◽  
Silvia Colucci ◽  
...  
Keyword(s):  
Bone Mineral ◽  
Human Subjects ◽  
Healthy Children ◽  
Mineral Density ◽  
Bone Status ◽  
Bone Mineral Status ◽  
Menopausal Women ◽  
Different Populations ◽  
Post Menopausal

Almost four years after the discovery of the anabolic action of irisin on bone in mice, ample clinical evidence is emerging in support of its additional physiological relevance in human bone. Irisin inversely correlates with sclerostin levels in adults with prediabetes and with vertebral fragility fractures in post-menopausal women. Furthermore, in athletes we observed a positive correlation between irisin and bone mineral density at different anatomical sites. Our group also described a positive association between serum irisin and bone status in healthy children and multivariate regression analysis showed that irisin is a stronger determinant of bone mineral status than bone alkaline phosphatase. In children with type 1 diabetes mellitus, serum irisin concentrations are positively associated with bone quality and with glycemic control following continuous subcutaneous insulin infusion. Additionally, our in vitro studies suggest the existence of a negative interplay between PTH and irisin biology and these results were also supported by the observation that post-menopausal women with primary hyperparathyroidism have lower levels of irisin compared to matched controls. In this review, we will focus on recent findings about circulating level of irisin in different populations of human subjects and its correlation with their bone status.

scholarly journals Cortical Bone Status Is Associated with Serum Osteoprotegerin Concentration in Men: The STRAMBO Study

2011 ◽  
Vol 96 (7) ◽  
pp. 2216-2226 ◽  
Author(s):  
P. Szulc ◽  
G. Hawa ◽  
S. Boutroy ◽  
N. Vilayphiou ◽  
M. Schoppet ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Bone Status
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