Quantitative analysis of the five marker compounds in Mori Cortex Radicis and its anti-inflammatory effects

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
CS Seo ◽  
HS Lim ◽  
SJ Jeong ◽  
HK Shin
2005 ◽  
Vol 53 (5) ◽  
pp. 508-514 ◽  
Author(s):  
Dan Yuan ◽  
Ying-ni Pan ◽  
Wen-wei Fu ◽  
Toshiaki Makino ◽  
Yoshihiro Kano

2014 ◽  
Vol 6 (11) ◽  
pp. 3763-3771 ◽  
Author(s):  
Jung-Hoon Kim ◽  
Hyeun-Kyoo Shin ◽  
Chang-Seob Seo

The quantification of 12 marker compounds in palmijihwang-hwan using a HPLC-PDA with a reversed-phase C18column and an amino column.


2015 ◽  
Vol 12 (3) ◽  
pp. 4773-4781 ◽  
Author(s):  
CHANG-SEOB SEO ◽  
HYE-SUN LIM ◽  
HYEKYUNG HA ◽  
SEONG EUN JIN ◽  
HYEUN-KYOO SHIN

2006 ◽  
Vol 54 (18) ◽  
pp. 6623-6628 ◽  
Author(s):  
Janine Zaugg ◽  
Olivier Potterat ◽  
Andreas Plescher ◽  
Bernd Honermeier ◽  
Matthias Hamburger

2020 ◽  
Vol 15 (1) ◽  
pp. 1934578X1989976 ◽  
Author(s):  
Al B. Bayazid ◽  
Jae G. Kim ◽  
Seo H. Park ◽  
Beong O. Lim

Mori Cortex Radicis (MCR) is a well-known Korean and Chinese folk medicine with anti-obesity, anti-inflammatory, anti-asthmatic, and hypoglycemic activities. This study was aimed to evaluate the total phenolic and flavonoid contents, as well as intracellular antioxidant and anti-inflammatory effects of water and 70% (v/v) ethanol extracts of MCR. The antioxidant activities of MCR extracts were determined with diphenyl-2-picrylhydrazyl and 2,2′-azinobis[3-ethylbenzothiazoline-6-sulfonic] scavenging activity assays. The suppressive activities of MCR extracts on the production of nitric oxide (NO*) and the expression of cytokines, c-Fos, activated p38-Mitogen-activated protein kinase (MAPK), and Nuclear factor Kappa B (NF-κB) and splenocytes proliferation in lipopolysaccharide-treated macrophages were determined. Furthermore, this study demonstrated the effects of MCR on reactive oxygen species production in murine macrophages. Mori Cortex Radicis restored deoxyribonucleic acid damages at higher concentrations of the extracts and significantly suppressed free radicals and NO* production. In this study, MCR significantly restored inflammatory responses and intracellular antioxidant activities in murine macrophages (RAW 264.7), which anticipated that MCR could be used as a natural anti-inflammatory agent.


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