Antitubercular study on stem bark of Albizia procera (ROXB.) BENTH using Microplate Alamar Blue assay (MABA)

Albizia procera commonly known as white siris is a large deciduous tree of the family Mimosideae, widely distributed throughout India. Traditionally the plant is used in convulsions, pain, delirium, cancer and septicemia. The decoction of bark is given for rheumatism, hemorrhage and is considered useful in treating pregnancy problems, for stomach ache and sinus.The preliminary phytochemical screening of ethanol extract of Albizia procera shows the presence of active constituents like flavonoids, phenolic compounds and tannins. Earlier studies show the flavonoids and phenolic compounds play major role in antitubercular activity. Based on this, we made an attempt to evaluate the antitubercular potential of this plant. The ethanolic extract and its fractions (Hexane and Ethyl acetate) were investigated for antitubercular activity using Alamar Blue dye method (MABA), in which Mycobacterium tuberculosis was sensitive upto 3.12μg/ml.The extract and fractions show better anti tubercular activity than streptomycin and potentially equal to pyrazinamide and ciprofloxacin. The observed activity may be due to the presence of flavonoids and phenolic compound which is confirmed by HPTLC. This investigation on stem bark of Albizia procera has the potential to be developed further into a natural Anti-TB drug.

ETHNOBOTANY STUDY OF Albizia procera IN TAMIANG HILL FOREST OF TANAH LAUT REGENCY AS A POPULAR SCIENTIFIC BOOK

Birik wood (Albizia procera) grows wild in the Tamiang hill forest and is often used by the local community. This study aims to describe the ethnobotany of the Albizia procera plant in the Tamiang hill forest area, Tanah Laut Regency and describe the validity and practicality of the contents of the popular scientific book on the Albizia procera plant. The research method used was descriptive research for ethnobotany studies and continued with the formative evaluation of the Tessmer test for the feasibility of the developed popular sciencetific book. The results showed that the Albizia procera plant had tree species, had white round stems, sympodial branches, double pinnate compound leaves, unlimited compound flowers, dry true fruit with pod and taproot type. Albizia procera plant is used as stomachache medicine, also used for road shade and livestock feed. The Albizia procera plant is believed by local people if it is burned it will cause the goat hair to fall out. Albizia procera plants are widely used as firewood, building materials and food materials. People in the hill forest area of Tamiang call the Albizia procera plant "birik wood" because of its speckled stems. The results of the development of teaching materials in the form of Popular Scientific Books on expert tests by 2 validators had very valid results, and the practicality of the content by 3 students had very good results. This popular scientific book is to support the Ethnobotany subject.