Quantitative analysis of triterpene lupeol and anti-inflammatory potential of the extracts of traditional pain-relieving medicinal plants Derris scandens, Albizia procera, and Diospyros rhodocalyx

: One of the principal causes of different disorders is an uncontrolled inflammatory response. Alkaloids, flavonoids, polyphenolic, proanthocyanidin, terpenoid, and steroid compounds are the main reasons for the anti-inflammatory activities of medicinal herbs and plants. The current manuscript introduces a series of potential anti-inflammatory plants, particularly those which are routines in Iranian and Chinese traditional herbal medicine, and simplifies the function and mechanisms of natural constituents for the prevention and treatment of inflammatory disorders. PubMed, Science Direct, Google Scholar, Wiley Online Library, Springer, Taylor, Francis, etc., have been used to search for collecting of scientific publications for a full evaluation of current documentation in the literature showing the importance of medicinal plants with anti-inflammatory characteristics and natural medicines. The most notable medicinal plants with anti-inflammatory activities are Baccharis dracunculifolia, Aconitum bulleyanum, Crateya adansonii, Alliums spp., Centella asiatica, Flos lonicerae, Corydalis dubia, Syringae folium, Coptis chinensis, Casearia decandra, Nigella sativa, Cannabis sativa, Tamarindus indica L., Glycyrrhiza glabra, Panax ginseng, Panax notoginseng, Pistacia vera, Smilax china, Scutellaria baicalensis, Rosemarinus officinalis, Moringa olifera, Pulsatilla radix, Pistacia atlantica, Rullia tuberose, Canarium album, Dodonaea polyandra, Forsythia suspense, Polygala tenuifolia, Radiz Isatidis, Hypericum sampsonii, Geranium koreanum, Typha capensis, Isatidis folium, Ginkgo biloba, Houttuynia cordata, snow lotus, etc. Herbal medicine mainly uses numerous parts of plants or combinations of them to prevent and remedy diseases and promote health. More investigations and clinical experiments are needed to provide more information on the importance of medicinal plants as well as their roles in the treatment and prevention of inflammatory diseases.

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Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents

Pharmacological Research ◽

10.1016/j.phrs.2018.11.001 ◽

2019 ◽

Vol 139 ◽

pp. 126-140 ◽

Cited By ~ 39

Author(s):

Shumaila Tasneem ◽

Bin Liu ◽

Bin Li ◽

M. Iqbal Choudhary ◽

Wei Wang

Keyword(s):

Medicinal Plants ◽

Molecular Pharmacology ◽

Anti Inflammatory

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Screening of medicinal plants used in Lesotho for anti-bacterial and anti-inflammatory activity

Journal of Ethnopharmacology ◽

10.1016/s0378-8741(99)00035-5 ◽

1999 ◽

Vol 67 (3) ◽

pp. 347-354 ◽

Cited By ~ 79

Author(s):

T.L Shale ◽

W.A. Stirk ◽

J. van Staden

Keyword(s):

Medicinal Plants ◽

Inflammatory Activity ◽

Anti Inflammatory

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Thymus algeriensis and Artemisia herba-alba Essential Oils: Chemical Analysis, Antioxidant Potential and In Vivo Anti-Inflammatory, Analgesic Activities, and Acute Toxicity

Molecules ◽

10.3390/molecules26226780 ◽

2021 ◽

Vol 26 (22) ◽

pp. 6780

Author(s):

Khadija El Ouahdani ◽

Imane Es-safi ◽

Hamza Mechchate ◽

Mohammed Al-zahrani ◽

Ashraf Ahmed Qurtam ◽

...

Keyword(s):

Antioxidant Activity ◽

Free Radical ◽

Medicinal Plants ◽

Essential Oils ◽

Iron Reduction ◽

Radical Scavenging ◽

Bioactive Molecules ◽

Potential Toxicity ◽

Thymus Algeriensis ◽

Anti Inflammatory

The study of bioactive molecules of natural origin is a focus of current research. Thymus algeriensis and Artemisia herba-alba are two medicinal plants widely used by the Moroccan population in the traditional treatment of several pathologies linked to inflammation. This study aimed to evaluate the single and combined antioxidant, anti-inflammatory and analgesic effects of the essential oils extracted from these two medicinal plants, and also their potential toxicity. Essential oils were extracted using hydro-distillation in a Clevenger-type apparatus. The antioxidant activity was evaluated by two methods: the scavenging of the free radical DPPH, and the reduction in iron. Anti-inflammatory activity was evaluated by evaluating the edema development induced by carrageenan injecting, while the analgesic power was evaluated according to the number of abdominal contortions induced by the intraperitoneal injection of acetic acid (0.7%). The acute oral toxicity was performed to assess the potential toxicity of the studied EOs, followed by an analysis of the blood biochemical parameters. The results of the two antioxidant tests indicated that our extract mixture exhibits good iron reduction capacity and very interesting DPPH free radical scavenging power, with an IC50 of around 4.38 ± 0.98 μg/mL higher than that of the benchmark antioxidant, BHT. The anti-inflammatory test demonstrated that the mixture administered orally at a dose of 150 mg/kg has a better activity, exceeding that of 1% Diclofenac, with a percentage of maximum inhibition of the edema of 89.99 ± 4.08. The number of cramps in the mice treated with the mixture at a dose of 150 mg/kg is significantly lower (29.80 ± 1.92) than those of the group treated with Tramadol (42.00 ± 2.70), respectively. The toxicity results show no signs of toxicity with an LD50 greater than 150 mg/Kg. These interesting results show that the two plants’ EOs had an important anti-inflammatory, analgesic, and antioxidant activity, and also a powerful synergistic effect, which encourages further in-depth investigations on their pharmacological proprieties.

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PHYTOSOCIOLOGICAL ANALYSIS AND FLORISTRIC DIVERSITY OF VANEESWARAM KAVU IN KANNUR DISTRICT, KERALA

Kongunadu Research Journal ◽

10.26524/krj197 ◽

2017 ◽

Vol 4 (2) ◽

pp. 19-23

Author(s):

Jeeshna M.V

Keyword(s):

Quantitative Analysis ◽

Species Diversity ◽

Medicinal Plants ◽

Vascular Plants ◽

Quantitative Approach ◽

Sacred Grove ◽

Sacred Groves ◽

Conservation Of Biodiversity

Sacred groves act as a treasure house for rare and medicinal plants. Apart from the quantitative analysis quantitative approach to sacred grove gives the potential species and importance of sacred grove, which is the main focuses of this work. There are many sacred grooves are present at Kannur district in whichVaneeswaram Kavu is one of the important one. The flora of sacred groves of has analysed taxonomically and phytosociologically. A total of 64 vascular plants falling under 61 genera and 43 families were documented. About 12 species are reported in the red listed category. In phytosociological studies specieslike, Elaeocarpus serratus, Erycibe paniculata and Scleria lithosperma were showing higher IVI. The devastation of species diversity in the study area represent there is an urgent need for regeneration of the species for conservation of biodiversity.

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PHYTOCHEMICAL SCREENING AND ANTIACNE ACTIVITY OF LEAVES EXTRACT OF LAGERSTROEMIA INDICA

International Journal of Pharmaceutical and Biological Science Archive ◽

10.32553/ijpba.v9i2.184 ◽

2021 ◽

Vol 9 (2) ◽

Author(s):

Vandana Vishwakarma ◽

Narendra Patel ◽

Prabhakar Budholiya

Keyword(s):

Quantitative Analysis ◽

Medicinal Plants ◽

Antioxidant Potential ◽

Aluminium Chloride ◽

Phytochemical Analysis ◽

Test Protocol ◽

Minor Ailments ◽

Pharmaceutical Industries ◽

Chloride Method

Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Secondary constituents contain alkaloids, flavonoids, phenol, sapon in, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti-inflammation activities. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In Indian Ayurvedic system, Lagerstroemia Indica (Lythraceae) are well-known plants used for major and minor ailments. The aim of the present study is to examine leaf of Lagerstroemia Indica for phytochemical profile, antioxidant potential, antimicrobial including anti acne activity. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by FolinsCiocalteau reagent method and aluminium chloride method respectively. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The present study concluded that the crude extract of Lagerstroemia Indica is a rich source of secondary phytoconstituents which impart significant antioxidant potential. The extract of Lagerstroemia Indica possess antimicrobial effectiveness againt P. acne and other microbes, In Vitro anti acne activity. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries. Keywords: Lagerstroemia Indica, Phytochemical, Antioxidant, Antiacne.

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