scholarly journals Takotsubo Cardiomyopathy Associated with Primary Hyperthyroidism Secondary to Toxic Multinodular Goiter

2015 ◽  
Vol 25 (05) ◽  
pp. e121-e122 ◽  
Author(s):  
William O'Callaghan ◽  
Elham Reda ◽  
Selvanayagam Niranjan ◽  
Dale Murdoch
Keyword(s):  
Takotsubo Cardiomyopathy ◽  
Multinodular Goiter ◽  
Toxic Multinodular Goiter ◽  
Primary Hyperthyroidism

scholarly journals Syndrome of Reduced Sensitivity to Thyroid Hormones: Two Case Reports and a Literature Review

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Anastasios Anyfantakis ◽  
Dimitrios Anyfantakis ◽  
Irene Vourliotaki
Keyword(s):  
Thyroid Hormone ◽  
Multinodular Goiter ◽  
Target Genes ◽  
Case Reports ◽  
Serum Levels ◽  
Free T4 ◽  
Laboratory Findings ◽  
Toxic Multinodular Goiter ◽  
High Doses ◽  
Primary Hyperthyroidism

Resistance to thyroid hormone (RTH) is an extremely rare dominantly inherited condition of impaired tissue responsiveness to thyroid hormone (TH). Most patients with RTH have mutations in the gene that encodes theβisoform of the receptor of thyroid hormone (THR-βgene). Mutant receptors are unable to activate or repress target genes. The majority of them are asymptomatic or rarely have hypo- or hyperthyroidism. RTH is suspected by the finding of persistent elevation of serum levels of free T3 (FT3) and free T4 (FT4) and nonsuppressed TSH. We present two cases of RTH diagnosed after total thyroidectomy. The first patient was initially diagnosed with primary hyperthyroidism due to toxic multinodular goiter. The second patient had undergone thyroidectomy for multinodular goiter 16 years before diagnosis of RTH. After thyroidectomy, although on relatively high doses of levothyroxine, both of them presented with the laboratory findings of RTH. Genetic analysis revealed RTH.

Rare association of primary hyperparathyroidism and toxic multinodular goiter

2018 ◽  
Author(s):  
Hamza Elfekih ◽  
Mouna Elleuch ◽  
Dorra Ghorbel ◽  
Faten Hadjkacem ◽  
Mouna Ammar ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Multinodular Goiter ◽  
Rare Association ◽  
Toxic Multinodular Goiter

Lack of Reported Mutations in a Japanese Case of Toxic Multinodular Goiter

ORL ◽  
2002 ◽  
Vol 64 (4) ◽  
pp. 275-277
Author(s):  
Masakazu Hanamitsu ◽  
Eiji Takeuchi ◽  
Tsuyoshi Kitanishi ◽  
Hironori Sakurai ◽  
Hiroshi Tanaka ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Japanese Case ◽  
Toxic Multinodular Goiter

Major post-operative complications of thyroid surgery: Preventable or not?

2009 ◽  
Vol 34 (3) ◽  
pp. 99-103 ◽  
Author(s):  
M.A. Majid ◽  
Md. Ibrahim Siddique
Keyword(s):  
Total Thyroidectomy ◽  
Vocal Cord ◽  
Thyroid Surgery ◽  
Multinodular Goiter ◽  
Vocal Cord Palsy ◽  
Subtotal Thyroidectomy ◽  
Permanent Hypoparathyroidism ◽  
Respiratory Obstruction ◽  
Operative Complications ◽  
Toxic Multinodular Goiter

Factors responsible for major complications following thyroid surgery in 598 patients were studied. Patients with non toxic multinodular goiter involving both lobes of thyroid constituted the maximum bulk subjected to thyroidectomy. The most frequent procedure was bilateral subtotal thyroidectomy. Reactionary hemorrhage occurred in 6 patients, all following bilateral procedures and among them 5 patients developed tension hematoma with respiratory obstruction despite the presence of a drain. Temporary vocal cord palsy was observed in 7 patients whereas one patient subjected to total thyroidectomy with neck dissection for papillary carcinoma of thyroid developed permanent right vocal cord palsy. Temporary parathyroid insufficiency was seen in 51 patients and one patient developed permanent hypoparathyroidism. Incidence of parathyroid insufficiency was higher in bilateral procedures as compared to unilateral ones. There was no operation related death in this series, but complications like hemorrhage, vocal cord palsy and parathyroid insufficiency following thyroid surgery are still a deep concern. Keywords: Complication; Post-operative; Thyroid surgeryOnline: 29-1-2009DOI: 10.3329/bmrcb.v34i3.1973     Bangladesh Med Res Counc Bull 2008; 34: 99-103. 

scholarly journals The Rare Coincidence: Nonrecurrent Laryngeal Nerve Pointed by a Zuckerkandl's Tubercle

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Emin Gurleyik ◽  
Sami Dogan ◽  
Omer Gunal ◽  
Mevlut Pehlivan
Keyword(s):  
Multinodular Goiter ◽  
Laryngeal Nerve ◽  
Inferior Laryngeal Nerve ◽  
Adjacent Structures ◽  
Toxic Multinodular Goiter ◽  
Posterior Extension ◽  
Right Lobe ◽  
Nonrecurrent Laryngeal Nerve ◽  
The Right ◽  
Case Based

The safety of thyroid operations mainly depends on complete anatomical knowledge. Anatomical and embryological variations of the inferior laryngeal nerve (ILN), of the thyroid gland itself and unusual relations between ILN and the gland threaten operation security are discussed. The patient with toxic multinodular goiter is treated with total thyroidectomy. During dissection of the right lobe, the right ILN which has nonrecurrent course arising directly from cervical vagus nerve is identified and fully isolated until its laryngeal entry. At the operation, we observe bilateral Zuckerkandl's tubercles (ZTs) as posterior extension of both lateral lobes. The left ILN has usual recurrent course in the trachea-esophageal groove. The right ZT is placed between upper and middle third of the lobe points the nonrecurrent ILN. The coincidence of non-recurrent ILN pointed by a ZT is rare anatomical and embryological feature of this case. Based on anatomical and embryological variations, we suggest identification and full exposure of ILN before attempting excision of adjacent structures, like the ZT which has surgical importance for completeness of thyroidectomy.

Evidence-based Management of Toxic Multinodular Goiter (Plummer’s Disease)

2008 ◽  
Vol 32 (7) ◽  
pp. 1278-1284 ◽  
Author(s):  
John R. Porterfield ◽  
Geoffrey B. Thompson ◽  
David R. Farley ◽  
Clive S. Grant ◽  
Melanie L. Richards
Keyword(s):  
Multinodular Goiter ◽  
Evidence Based ◽  
Toxic Multinodular Goiter ◽  
Plummer's Disease ◽  
Plummer’S Disease

scholarly journals Változások a pajzsmirigybetegségek radiojódkezelésében

2016 ◽  
Vol 157 (3) ◽  
pp. 83-88
Author(s):  
András Konrády
Keyword(s):  
Multinodular Goiter ◽  
Radioiodine Therapy ◽  
Treatment Protocol ◽  
Treatment Results ◽  
Radioiodine Uptake ◽  
Risk Patients ◽  
Toxic Multinodular Goiter ◽  
Prospective Trials ◽  
Immunogenic Hyperthyroidism ◽  
Recombinant Human Thyrotropin

Radioiodine therapy for benign and malignant thyroid diseases was introduced about 70 years ago, however, there is still a lack of consensus regarding indications, doses and procedure. This review covers treatment results in immunogenic hyperthyroidism including the problem of orbitopathy. Radioiodine therapy for toxic and non-toxic multinodular goiter is also discussed with striking possibility of enhanching the radioiodine uptake. In this respect the recombinant human thyrotropin should be mentioned. Thyroid cancer treatment protocol has changed, too, due to ineffectivity in low-risk patients. More attention is needed to the carcinogenecity of radioiodine. The numerous problems mentioned above require large and well-designed prospective trials to resolve the fundamental questions. The author emphasizes that radioiodine dose should be administered in doses as low as reasonably achievable. Orv. Hetil., 2016, 157(3), 83–88.

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