scholarly journals Primary Spinal Epidural Lymphoma As a Cause of Spontaneous Spinal Anterior Syndrome: A Case Report and Literature Review

2017 ◽  
Vol 78 (01) ◽  
pp. e1-e4
Author(s):  
M. Córdoba-Mosqueda ◽  
J. Guerra-Mora ◽  
M. Sánchez-Silva ◽  
R. Vicuña-González ◽  
A. Torre
Keyword(s):  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Cord Compression ◽  
Thoracic Pain ◽  
Case Presentation ◽  
Large B Cell Lymphoma ◽  
Paravertebral Mass ◽  
Spinal Epidural ◽  
Radicular Compression ◽  
New Onset

Background Primary spinal epidural lymphoma (PSEL) is one of the rarest categories of tumors. Spinal cord compression is an uncommon primary manifestation and requires to be treated with surgery for the purpose of diagnosis and decompression. Case Presentation A 45-year-old man presented with a new onset thoracic pain and progress to an anterior spinal syndrome with hypoesthesia and loss of thermalgesia. Magnetic resonance image showed a paravertebral mass that produces medullary compression at T3. The patient was taken up to surgery, where the pathology examination showed a diffuse large B-cell lymphoma. Conclusions PSEL is a pathological entity, which must be considered on a middle-aged man who began with radicular compression, and the treatment of choice is decompression and biopsy. The specific management has not been established yet, but the literature suggests chemotherapy and radiotherapy; however, the outcome is unclear.

scholarly journals Metachronous Diffuse Large B-Cell Lymphoma of the Breasts: A Case Report and Literature Review

2021 ◽  
Vol 14 (6) ◽  
Author(s):  
Mastane Saneii ◽  
Pedram Fadavi ◽  
Kambiz Novin ◽  
Maryam Garousi
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Maximum Level ◽  
Treatment Modalities ◽  
Regional Lymph Nodes ◽  
Case Presentation ◽  
Large B Cell Lymphoma ◽  
One Year ◽  
Large B Cell

Introduction: PBL is a rare form of extranodal lymphoma. The most common pathology is diffuse large B cell lymphoma and most patients are diagnosed at stages 1 and 2. The therapeutic options undertaken so far include surgery, radiotherapy, and chemotherapy Case Presentation: The patient was a 54-year old woman with localized primary breast DLBCL. The patient underwent 6 courses of chemotherapy with an RCHOP regimen followed by radiotherapy of the breast and regional lymph nodes with a 40 Gy dose. The patient was in complete remission on PET scan 3 months later. Around one year after, the patient experienced relapse in the contralateral breast. Conclusions: In the pattern of relapse of patients, there is a tendency for extranodal relapse. In some studies maximum level of relapse occurring in CNS and some advocate CNS prophylaxis in these patients. The best outcome is for patients treated with chemotherapy including rituximab followed by radiation. We reviewed some studies in the aspect of treatment modalities and site of relapsed.

scholarly journals Primary spinal epidural non‐Hodgkin's diffuse large B‐cell lymphoma: A case report

2020 ◽  
Vol 8 (11) ◽  
pp. 2276-2280
Author(s):  
Nishan Babu Pokhrel ◽  
Rohit Prasad ◽  
Sushil Paudel ◽  
Dinesh Kafle ◽  
Rohit Kumar Pokharel
Keyword(s):  
Case Report ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Spinal Epidural ◽  
Large B Cell

scholarly journals Primary spinal epidural diffuse large B-cell lymphoma with paraplegia as the first manifestation: a case report

2019 ◽  
Vol Volume 12 ◽  
pp. 6497-6501
Author(s):  
Yefei Shu ◽  
Anlong Wang ◽  
Li Yi ◽  
Xiaofeng Xu ◽  
Wei Yang
Keyword(s):  
Case Report ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Spinal Epidural ◽  
Large B Cell

scholarly journals Primary Dumbbell-Shaped Lymphoma of the Thoracic Spine: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Antonio Meola ◽  
Paolo Perrini ◽  
Nicola Montemurro ◽  
Paolo di Russo ◽  
Giacomo Tiezzi
Keyword(s):  
Thoracic Spine ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Cord Compression ◽  
Pathological Examination ◽  
Subtotal Resection ◽  
Large B Cell Lymphoma ◽  
One Year

Primary spinal non-Hodgkin’s lymphoma is extremely rare, and the occurrence of spinal dumbbell-shaped lymphoma is exceptional. We present a case of primary spinal dumbbell-shaped lymphoma to clarify the diagnosis and the management of these lesions. A 45-year-old man presented with sensory symptoms for 8 months. Magnetic resonance imaging of the thoracic spine demonstrated a dumbbell-shaped lesion at the D4–D6 level with spinal cord compression and right foraminal extension at D4–D5 level. The patient underwent D4–D6 laminectomy, with a subtotal resection of the mass. Diffuse large B-cell lymphoma was diagnosed in the pathological examination. He underwent local spinal radiotherapy and chemotherapy. Follow-up evaluation at one year demonstrated no evidence of relapse. Although highly unusual, lymphoma should be included in the differential diagnosis for spinal dumbbell-shaped tumours. After surgery and adjuvant therapy a long-term clinical and neuroradiological followup is mandatory.

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