Einfluß einer dreidimensionalen Datenstabilisierung in der Radionuklidventrikulographie auf den statistischen Zählfehler der Ejektionsfraktion

1990 ◽  
Vol 29 (03) ◽  
pp. 109-112
Author(s):  
J. Mester ◽  
E. Henze ◽  
R. Ochsenkühn ◽  
R. Lietzenmayer ◽  
R. Weller ◽  
...  
Keyword(s):  
Left Ventricular Volume ◽  
Ventricular Volume ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Statistical Uncertainty ◽  
Ventricular Ejection Fraction ◽  
3 Dimensional ◽  
Systematical Error ◽  
Before And After ◽  
Statistical Noise

The suitability of a 3-dimensional filter in diminishing the statistical noise of left ventricular volume curves without any systematical error in the left ventricular ejection fraction (EF) was investigated. The EF values were compared in 50 studies on 24 patients. There was no significant systematical difference between the EFs before and after filtering. The filter diminishes the statistical uncertainty of the EF by a factor of 0.47. Therefore, the method may possibly be employed in processing the left ventricular volume curves.

Three-dimensional vectorcardiographic characteristics of breast cancer patients treated with chemotherapy

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
T Liu ◽  
Y Wang ◽  
X Yin ◽  
X Liang ◽  
Y Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Three Dimensional ◽  
Area Under The Curve ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Breast Cancer Patients ◽  
Ventricular Ejection Fraction ◽  
3 Dimensional ◽  
Before And After ◽  
Echocardiographic Parameters

Abstract Funding Acknowledgements Type of funding sources: None. Background  Patients receiving chemotherapy for breast cancer (BC) may develop cardiac electrophysiological abnormalities. The aim of this study is to examined possible alterations in cardiac electrophysiological parameters detected by three-dimensional vectorcardiograms (3D-VCGs) in BC patients who received chemotherapy. Methods This was a prospective single-center cohort study conducted. Patients with BC referred for chemotherapy from May 1, 2019, to October 1, 2019 were invited to participate in the study. 3D-VCG and echocardiography were recorded at rest four times (baseline, after the first cycle, after third cycles and at the end of the regimen, respectively).  Results  A total of 63 patients were included. Compared with baseline, decreases in 3-dimensional maximum T vector magnitude (TVM) (0.29 ± 0.10 vs. 0.25 ± 0.10mV; p < 0.05) and 3-dimensional T/QRS ratio (0.26 ± 0.11 vs. 0.21 ± 0.11; p < 0.05) were observed by the end of chemotherapy regimen, while echocardiographic parameters showed no significant variation before and after chemotherapy (all P > 0.05). Maximum TVM showed a significant positive correlation with left ventricular ejection fraction (LVEF) (all p < 0.05). Furthermore, the cut-off value with 0.23 of 3-dimensional T/QRS ratio (the area under the curve [AUC] 0.725) for differentiating LVEF reduction ≥10% following initiation of chemotherapy. The AUC of the front plane T/QRS ratio and horizontal plane T/QRS ratio for the detection of an LVEF reduction ≥10% was 0.725 and 0.763, respectively. Conclusions  3D-VCGs can be used to detect electrophysiological abnormalities in BC patients receiving chemotherapy. Subclinical cardiac dysfunction can be revealed by 3D-VCGs before alterations in traditional echocardiographic parameters.

scholarly journals Comparative analysis of echocardiography, multispiral computed tomography, myocardial perfusion scintigraphy to evaluate left ventricular volume and left ventricular ejection fraction

2013 ◽  
Vol 94 (1) ◽  
pp. 39-43
Author(s):  
A S Galyavich ◽  
A Y Rafikov ◽  
G B Saifullina
Keyword(s):  
Computed Tomography ◽  
Comparative Analysis ◽  
Left Ventricular Ejection Fraction ◽  
Ejection Fraction ◽  
Left Ventricular Volume ◽  
Ventricular Volume ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Significant Difference

Aim. To perform a comparative analysis of multislice computed tomography (MSCT), echocardiography and single photon emission computed tomography (SPECT) in the evaluation of left ventricular end-diastolic volume (LV EDV) and left ventricular ejection fraction (LVEF). Methods. The study included 44 patients (15 female, 29 male) aged of 21 to 73 years (mean age 55±11 years). LV EDV and LVEF were assessed by noninvasive MSCT coronary angiography. echocardiography and SPECT were also performed. Results. There was a statistically significant difference found between the LV EDV medians for the following pairs: MSCT vs Quantitative Gated SPECT (QGS), MSCT vs SPECT using 4D MSPECT regimen, MSCT vs echocardiography. There was no statistically significant difference determined for the following pairs: echocardiography vs SPECT, QGS SPECT vs 4D MSPECT. Difference between the LV EDV were calculated using the Bland-Altman method as following: MSCT vs echocardiography - 55±33 ml, MSCT vs QGS SPECT - 38±29 ml, MSCT vs 4D MSPECT - 30±33 ml. Differences in the LVEF evaluation methods were: MSCT vs echocardiography - 2,5±7,2%, MSCT vs QGS SPECT - 0,9±8,3%, MSCT vs 4D MSPECT - 1,2±8,1%. The highest LV EDV values were registered by MSCT, the lowest - by echocardiography, with the values registered by SPECT lying in between MSCT and echocardiography volumes. Conclusion. MSCT, echocardiography and SPECT present different left ventricular volume and similar LVEF data.

The Assessment of Left Ventricular Ejection Fraction in Patients with Ischaemic Heart Disease by Contrast Ventriculography and Nuclear Angiography

1977 ◽  
Vol 53 (1) ◽  
pp. 55-61 ◽  
Author(s):  
A. L. Muir ◽  
W. J. Hannan ◽  
H. M. Brash ◽  
V. Baldwa ◽  
H. C. Miller ◽  
...  
Keyword(s):  
Heart Disease ◽  
Left Ventricular Ejection Fraction ◽  
Ejection Fraction ◽  
Ischaemic Heart Disease ◽  
Ventricular Volume ◽  
Left Ventricular ◽  
Ventricular Ejection ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Contrast Ventriculography

1. In 18 patients with ischaemic heart disease left ventricular ejection fraction, measured by two different nuclear angiographic methods, has been compared with ejection fraction measured by single-plane contrast angiography. 2. The first nuclear angiographic technique involves detection of variation in the radioactivity from the left ventricle during the initial passage of a bolus of 99Tcm-labelled human serum albumin injected intravenously; the second is our own modification of a ‘gated’ method, which accumulates the radioactivity detected during the continuing recirculation of the plasma bound radioisotope, so presenting an ‘averaged’ ventricular volume curve. 3. Ejection fraction, measured by the ‘bolus’ method, is lower than that measured either by contrast ventriculography or by the ‘gated’ method. This may be due to a damping effect. 4. Ejection fraction measured by the ‘gated’ method is well correlated with that measured by contrast ventriculography (r = 0·89). 5. Our modification of the ‘gated’ method, which presents the changes in ventricular volume throughout the cardiac cycle, without needing computer facilities, is a useful non-invasive means for assessment of left ventricular function.

Trastuzumab-Induced Cardiotoxicity: Clinical and Prognostic Implications of Troponin I Evaluation

2010 ◽  
Vol 28 (25) ◽  
pp. 3910-3916 ◽  
Author(s):  
Daniela Cardinale ◽  
Alessandro Colombo ◽  
Rosalba Torrisi ◽  
Maria T. Sandri ◽  
Maurizio Civelli ◽  
...  
Keyword(s):  
At Risk ◽  
Cardiac Dysfunction ◽  
Troponin I ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Trastuzumab Therapy ◽  
Before And After ◽  
Patients At Risk ◽  
Prognostic Implications

Purpose Treatment of breast cancer with trastuzumab is complicated by cardiotoxicity in up to 34% of the patients. In most patients, trastuzumab-induced cardiotoxicity (TIC) is reversible: left ventricular ejection fraction (LVEF) improves after trastuzumab withdrawal and with, or sometimes without, initiation of heart failure (HF) therapy. The reversibility of TIC, however, is not foreseeable, and identification of patients at risk and of those who will not recover from cardiac dysfunction is crucial. The usefulness of troponin I (TNI) in the identification of patients at risk for TIC and in the prediction of LVEF recovery has never been investigated. Patients and Methods In total, 251 women were enrolled. TNI was measured before and after each trastuzumab cycle. LVEF was evaluated at baseline, every 3 months during trastuzumab therapy, and every 6 months afterward. In case of TIC, trastuzumab was discontinued, and HF treatment with enalapril and carvedilol was initiated. TIC was defined as LVEF decrease of > 10 units and below 50%. Recovery from TIC was defined as LVEF increase above 50%. Results TIC occurred in 42 patients (17%) and was more frequent in patients with TNI elevation (TNI+; 62% v 5%; P < .001). Twenty-five patients (60%) recovered from TIC. LVEF recovery occurred less frequently in TNI+ patients (35% v 100%; P < .001). At multivariate analysis, TNI+ was the only independent predictor of TIC (hazard ratio [HR], 22.9; 95% CI, 11.6 to 45.5; P < .001) and of lack of LVEF recovery (HR, 2.88; 95% CI,1.78 to 4.65; P < .001). Conclusion TNI+ identifies trastuzumab-treated patients who are at risk for cardiotoxicity and are unlikely to recover from cardiac dysfunction despite HF therapy.

scholarly journals The functional state of the heart in women prior to extracorporeal fertilization and its dynamics after stimulation of superovulation

2020 ◽  
Vol 10 (6) ◽  
pp. 59-65
Author(s):  
Victoria V. Vakareva ◽  
Marina V. Avdeeva ◽  
Larisa V. Scheglova ◽  
Varvara V. Popova ◽  
Pavel B. Voronkov
Keyword(s):  
Left Ventricular Ejection Fraction ◽  
Ejection Fraction ◽  
Functional State ◽  
Left Ventricular ◽  
Ventricular Ejection ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Healthy Women ◽  
Myocardial Stress ◽  
Before And After

The purpose of the work to study echocardiographic parameters before and after the induction of superovulation to determine the nature of the effect of extracorporeal fertilization on the functional state of the cardiovascular system in healthy women of reproductive age. Materials and methods. The article presents the results of clinical and instrumental examination of 80 practically healthy women (mean age 32.3 3.5 years). All women were examined twice before and after induction of superovulation during extracorporeal fertilization. Results. It was established that a decrease in the stroke volume of blood (p 0.001) was accompanied by a compensatory increase in heart rate (p 0.001). These changes ensured the stability of the minute blood volume after induction of superovulation (before 51.1 1.1 ml; after 52.1 1.2 ml; p 0.05). After induction of superovulation in women, an increase in the integral systolic index of cardiac remodeling was noted (before 108.7 2.5 units; after 118.5 4.7 units; p 0.001), an indicator of myocardial stress in systole (before 111.5 6.7 dyne/cm2; after 127.3 7.4 dyne/cm2; p 0.001) and the indicator of myocardial stress in diastole (before 139.4 6.8 dyne/cm2; after 165.7 7.9 dyne/cm2; p 0.001). In practically healthy women, after induction of superovulation, the left ventricular ejection fraction increased (before 71.3 4.2%; after 74.8 4.1%; p 0.001). The revealed dynamics is regarded as a response of the myocardium to a change in the hormonal background during superovulation induction. This is evidenced by the correlation between the estradiol level and the left ventricular ejection fraction (r = 0.36; p 0.05). Conclusion. Induction of superovulation does not adversely affect systolic and diastolic function of the left ventricle. However, after these manipulations there is an increase in systolic and diastolic myocardial stress, which reflects myocardial stress in response to hemodynamic changes. Remodeling indices are more informative for evaluating maladaptive and adaptive variants of myocardial changes in healthy women than traditional echocardiographic indicators. In this regard, remodeling indices should be used as additional indicators of the functional state of the heart in women before and after the induction of superovulation in vitro fertilization.

Sign in / Sign up

Export Citation Format

Share Document