Information System for Post-marketing Drug Surveillance Scheme on Small Computers

1982 ◽  
Vol 21 (04) ◽  
pp. 181-186 ◽  
Author(s):  
M. A. A. Moussa

A drug information system (DARIS) has been created for handling reports on suspected drug reactions. The system is suitable for being run on desktop computers with a minimum of hardware requirements: 187 K read/write memory, flexible or hard disc drive and a thermal printer. The data base (DRUG) uses the QUERY and IMAGE programming capabilities for data entry and search. The data base to statistics link program (DBSTAT) enables data transfer from the data base into a file for statistical analysis and signalling suspected adverse drug reactions.The operational, medical and statistical aspects of the general population voluntary adverse drug reaction monitoring programme—recently initiated in the State of Kuwait—are described.

Author(s):  
M.F. Schmid ◽  
R. Dargahi ◽  
M. W. Tam

Electron crystallography is an emerging field for structure determination as evidenced by a number of membrane proteins that have been solved to near-atomic resolution. Advances in specimen preparation and in data acquisition with a 400kV microscope by computer controlled spot scanning mean that our ability to record electron image data will outstrip our capacity to analyze it. The computed fourier transform of these images must be processed in order to provide a direct measurement of amplitudes and phases needed for 3-D reconstruction.In anticipation of this processing bottleneck, we have written a program that incorporates a menu-and mouse-driven procedure for auto-indexing and refining the reciprocal lattice parameters in the computed transform from an image of a crystal. It is linked to subsequent steps of image processing by a system of data bases and spawned child processes; data transfer between different program modules no longer requires manual data entry. The progress of the reciprocal lattice refinement is monitored visually and quantitatively. If desired, the processing is carried through the lattice distortion correction (unbending) steps automatically.


1983 ◽  
Vol 22 (03) ◽  
pp. 135-148 ◽  
Author(s):  
T. Kitaguchi ◽  
T. Nojiri ◽  
S. Suzuki ◽  
T. Fukita ◽  
T. Kawana

In order to meet the multifarious needs for drug information and to cope with the post-marketing surveillance of drugs adequately, an on-line drug information network, which is composed of two data bases, clinical case record data base and literature data base, has been developed. Primary considerations in designing these systems were input of clean data, accurate input, insuring that no ADRs are overlooked, accumulation of the latest data, saving manpower required for processing, and processing large quantities of data. This system is also designed to input and to output in Japanese character.


1974 ◽  
Vol 13 (03) ◽  
pp. 125-140 ◽  
Author(s):  
Ch. Mellner ◽  
H. Selajstder ◽  
J. Wolodakski

The paper gives a report on the Karolinska Hospital Information System in three parts.In part I, the information problems in health care delivery are discussed and the approach to systems design at the Karolinska Hospital is reported, contrasted, with the traditional approach.In part II, the data base and the data processing system, named T1—J 5, are described.In part III, the applications of the data base and the data processing system are illustrated by a broad description of the contents and rise of the patient data base at the Karolinska Hospital.


1988 ◽  
Vol 22 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Michael H. Dong ◽  
Charles Anello ◽  
John P. Juergens ◽  
Wayne M. Turner ◽  
Alan Gelberg ◽  
...  

1993 ◽  
Vol 12 (24) ◽  
pp. 2383-2393 ◽  
Author(s):  
Michaela Praus ◽  
Fritz Schindel ◽  
Reinhard Fescharek ◽  
Sabine Schwarz

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