Brown adipose tissue derived media impairs chemosensitivity in non-small lung cancer cells in the context of cancer cachexia

2019 ◽  
Author(s):  
A Frille ◽  
H Kuhn ◽  
T Ebert ◽  
HJ Seyfarth ◽  
H Wirtz
Keyword(s):  
Lung Cancer ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cancer Cells ◽  
Cancer Cachexia ◽  
Lung Cancer Cells ◽  
Brown Adipose

The absence of Caspase 1/11 leads to fat tissue modulation and a anti-tumor activity of Brown adipose tissue against breast cancer cells

2018 ◽  
Vol 14 (11) ◽  
pp. S191
Author(s):  
Luis Henrique L Correa ◽  
Lívia S Sant'Ana ◽  
Aline M Martins ◽  
Kelly G Magalhães ◽  
Marcos N Eberlin
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Fat Tissue ◽  
Caspase 1 ◽  
Brown Adipose ◽  
Anti Tumor Activity

Role of brown adipose tissue in metabolic syndrome, aging, and cancer cachexia

2017 ◽  
Vol 12 (2) ◽  
pp. 130-138 ◽  
Author(s):  
Meng Dong ◽  
Jun Lin ◽  
Wonchung Lim ◽  
Wanzhu Jin ◽  
Hyuek Jong Lee
Keyword(s):  
Metabolic Syndrome ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cancer Cachexia ◽  
Brown Adipose

scholarly journals Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice

2012 ◽  
Vol 72 (17) ◽  
pp. 4372-4382 ◽  
Author(s):  
Maria Tsoli ◽  
Melissa Moore ◽  
Dominic Burg ◽  
Arran Painter ◽  
Ryland Taylor ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Lipid Metabolism ◽  
Brown Adipose Tissue ◽  
Cancer Cachexia ◽  
Brown Adipose

scholarly journals A role of active brown adipose tissue in cancer cachexia?

2012 ◽  
pp. e11
Author(s):  
Emiel Beijer ◽  
Janna Schoenmakers ◽  
Guy Vijgen ◽  
Fons Kessels ◽  
Anne-Marie Dingemans ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cancer Cachexia ◽  
Careful Consideration ◽  
Positron Emission ◽  
Animal Data ◽  
Brown Adipose ◽  
Computed Tomography Scanning ◽  
Quantitative Impact

Until a few years ago, adult humans were not thought to have brown adipose tissue (BAT). Now, this is a rapidly evolving field of research with perspectives in metabolic syndromes such as obesity and new therapies targeting its bio-energetic pathways. White, brown and socalled brite adipose fat seem to be able to trans-differentiate into each other, emphasizing the dynamic nature of fat tissue for metabolism. Human and animal data in cancer cachexia to date provide some evidence for BAT activation, but its quantitative impact on energy expenditure and weight loss is controversial. Prospective clinical studies can address the potential role of BAT in cancer cachexia using 18F-fluorodeoxyglucose positron emission tomography-computed tomography scanning, with careful consideration of co-factors such as diet, exposure to the cold, physical activity and body mass index, that all seem to act on BAT recruitment and activity.

Sign in / Sign up

Export Citation Format

Share Document