A Comparison of Current Prophylactic Therapy in Canada and the United Kingdom
A survey of Canadian and British physicians actively treating hemophiliacs was undertaken to assess whether the difference in the two countries’ health care delivery systems influenced their attitudes to prophylactic therapy. Questionnaires defining prophylactic therapy and relating its use to a number of activities were sent to directors of hemophilia treatment centres representing adequate geographic coverage in both countries. 47 replies were received (10/13 Canadian and 37/40 British). 50% of the United Kingdom (UK) physicians used prophylactic therapy on occasion as compared to 92% of Canadian physicians. However, only 20% UK physicians versus 80% Canadian used it on a routine basis for selected patients. 43% British physicians compared to 50% Canadian gave prophylaxis prior to certain athletic or social events. The mean dose of Factor VIII or IX given by Canadian physicians was higher and individual doses were given more frequently. The increased acceptability of this form of therapy in Canada may be related to easier availability of Factor concentrates and a more flexible health care system.