Comparative Effectiveness of the Homeopathic Preparation Traumeel S in Third Molar Extraction Surgery: A Preliminary Triple-Blind Clinical Trial

Abstract Background and Aim This preliminary study aimed to evaluate whether a homeopathic preparation (Traumeel S) might be a good option to control post-operative outcomes (pain, edema and trismus) associated with surgical removal of mandibular third molar teeth. The null hypothesis was that Traumeel S is not different from dexamethasone (gold standard) in controlling these post-operative inflammatory complications. Methods A randomized, “split-mouth”, triple-blind clinical trial was conducted. Seventeen healthy patients with a mean age of 20.94 ( ± 5.83) years had their lower asymptomatic bilateral third molars removed. Patients were randomized to receive Traumeel S or dexamethasone pre-operatively by injection into the masseter muscle; each patient acted as his/her own control. At 24, 48, 72 hours and 7 days after the surgery, the pain was evaluated according to a visual analog scale, edema through linear measurements of the face, and trismus through the maximum buccal opening. Wilcoxon statistics or paired t-test were used, and a significance level of 95% was adopted. Results For pain, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone after 24 hours, 72 hours, and 7 days. For edema, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone at all post-operative evaluations. For mouth opening, the results for Traumeel S were not different (p > 0.05) from those of dexamethasone at 72 hours and 7 days after third molar extraction. Conclusion With the exception of some early post-operative findings, the null hypothesis is not rejected. Traumeel S might be a good alternative approach to dexamethasone for controlling pain, edema and trismus after third molar removal.

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Effect of Age, Gender, Side and Impaction Types on Surgical Difficulty During Mandibular Third Molar Extraction.

Medical Journal of Shree Birendra Hospital ◽

10.3126/mjsbh.v17i2.18950 ◽

2018 ◽

Vol 17 (2) ◽

pp. 11

Author(s):

Krishna Gopal Bhuju ◽

Sujita Shrestha ◽

Riwaj Karki ◽

Sameer Aryal

Keyword(s):

Third Molar ◽

Objective Measure ◽

Operation Time ◽

Significance Level ◽

Third Molar Extraction ◽

Mandibular Third Molar ◽

Duration Of Surgery ◽

Surgical Difficulty ◽

Effect Of Age ◽

Molar Extraction

Aim: To study the effect of age, gender, side and impaction types on surgical difficulty during mandibular third molar extraction through the data collected over a period of one year by single maxillofacial surgeon. All the extractions were performed under the same environment and conditions.Methods: Descriptive clinical study of 401 patients was carried out between the ages of 16 to 45years. Age, gender, impaction side and impaction types (according to the winter classification) were recorded on proforma. Duration of surgery for each patient was recorded after starting incision to the completion of suture which was divided into less than 10 minutes (mild), 11 to 20 minutes (moderate) and above 21 minutes (severe). Pearson’s Chi-square test was used for data analysis and significance level was less than or equal to 0.05.Results: Among 401 participants, 225 (56.1%) were male and 176 (43.9%) were female. Mean age was 31.5 years and mean operation time was 17.59 minutes. After statistical analysis there was a significant correlation among gender and side of impaction where p value is 0.043 0.048 respectively.Conclusion: There is a statistically significant correlation between gender and side of impaction with duration of surgery which is considered as the objective measure of surgical difficulty whereas age and impaction types didn’t show any significant correlation.

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Celecoxib versus ibuprofen in controlling postoperative symptomatology of third molar extraction: a randomized double-blind clinical trial

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2019.03.185 ◽

2019 ◽

Vol 48 ◽

pp. 60-61

Author(s):

B. Barreiro ◽

M. Campos ◽

F. Andriola ◽

R. Berthold ◽

C. Heitz ◽

...

Keyword(s):

Clinical Trial ◽

Third Molar ◽

Double Blind ◽

Third Molar Extraction ◽

Double Blind Clinical Trial ◽

Molar Extraction

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A Preliminary Report on: Prospective Randomized Controlled Clinical Trial to Determine Most Effective Postoperative Analgesia after Third Molar Extraction

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2019.06.048 ◽

2019 ◽

Vol 77 (9) ◽

pp. e28

Author(s):

C. Dayama ◽

D. Havard ◽

K. Burns

Keyword(s):

Clinical Trial ◽

Postoperative Analgesia ◽

Preliminary Report ◽

Third Molar ◽

Controlled Clinical Trial ◽

Randomized Controlled Clinical Trial ◽

Randomized Controlled ◽

Third Molar Extraction ◽

Molar Extraction

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Oral pregabalin for postoperative pain relief after third molar extraction: a randomized controlled clinical trial

Clinical Oral Investigations ◽

10.1007/s00784-015-1657-3 ◽

2015 ◽

Vol 20 (7) ◽

pp. 1819-1826 ◽

Cited By ~ 7

Author(s):

Maria Victoria Olmedo-Gaya ◽

Francisco J. Manzano-Moreno ◽

Rafael Galvez-Mateos ◽

Maria Paloma González-Rodriguez ◽

Cristina Talero-Sevilla ◽

...

Keyword(s):

Clinical Trial ◽

Postoperative Pain ◽

Pain Relief ◽

Third Molar ◽

Postoperative Pain Relief ◽

Controlled Clinical Trial ◽

Randomized Controlled Clinical Trial ◽

Randomized Controlled ◽

Third Molar Extraction ◽

Molar Extraction

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“Importance of Plasma Rich Growth Factors In Tooth Socket-In Concern of DRY SOCKET” (A Comperative Study)

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v7i09.016 ◽

2020 ◽

Vol 7 (09) ◽

pp. 5039-5043

Author(s):

Dr santosh Mishra ◽

Shukla M ◽

Arya V

Keyword(s):

Growth Factors ◽

Healing Rate ◽

Third Molar ◽

Wilcoxon Test ◽

Control Group ◽

Surgical Removal ◽

Dry Socket ◽

Third Molar Extraction ◽

Significant Difference ◽

Molar Extraction

Introduction: The high prevalence of dry socket or alveolar osteitis (AO) is of concern in surgical removal of third molars. The aim of the present study was to assess the preventive effect of plasma rich in growth factors (PRGF) on AO and also its effect on pain management and healing acceleration in third molar extraction sockets of high-risk patients. Materials and Methods: This split-mouth, double-blind clinical trial included 40 bilateral third molar extractions (80 sockets) with at least one identified risk factor for AO. PRGF was obtained from patient’s own blood, based on manufacturer’s instruction, and blindly placed in one of the two bilateral sockets (PRGF group; n = 20) of each patient. The contralateral socket was treated with a placebo (control group; n = 20). Samples were evaluated for AO and pain incidence on days 2, 3 and 4 and healing and infection on days 3 and 7. Data were analyzed in SPSS v16 using Wilcoxon test. Results: There was a significant difference in dry socket and pain incidence and healing rate between the two groups. Intensity of pain and occurrence of dry socket in the study group was lower than the controls. Also the healing rate was higher (P < 0.05) for the PRGF group. No sign of infection was seen in either group. Conclusion: The application of PRGF may significantly reduce the incidence of AO or its associated pain and may accelerate healing. The prophylactic use of PRGF following third molar extraction may be suggested especially in the patients at risk of AO.

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Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Biotechnology & Biotechnological Equipment ◽

10.1080/13102818.2016.1249408 ◽

2016 ◽

Vol 31 (1) ◽

pp. 182-186

Author(s):

Moises A. Franco-Molina ◽

Edgar Mendoza-Gamboa ◽

Erika E. Coronado-Cerda ◽

Diana Zarate-Triviño ◽

Juan E. Arizpe-Coronado ◽

...

Keyword(s):

Clinical Trial ◽

Third Molar ◽

The Third ◽

Third Molar Extraction ◽

Molar Extraction

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Pathological fracture of the jaw due to osteomyelitis after a third molar extraction

ARCHIVES OF HEALTH INVESTIGATION ◽

10.21270/archi.v10i4.4942 ◽

2021 ◽

Vol 10 (4) ◽

pp. 637-640

Author(s):

Thais Pimentel ◽

Henrique Hadad ◽

Laís Kawamata Jesus ◽

Luara Teixiera Colombo ◽

Albertino Gomes Alcantara ◽

...

Keyword(s):

Pathological Fracture ◽

Third Molar ◽

Mouth Opening ◽

Signs And Symptoms ◽

Bone Fragility ◽

Genetic Condition ◽

Limited Mouth Opening ◽

Third Molar Extraction ◽

Local Bone ◽

Molar Extraction

The osteomyelitis is an inflammatory process in bone tissue caused by an infection, commonly related to anaerobic pathogens, frequently Staphylococcus aureus and Streptococcus sp. Several causes have been related such as dentoalveolar infection, trauma, radiation and genetic condition, but it is not common after surgery for third molar extractions, especially in healthy patients. The symptoms of chronic osteomyelitis usually include signs and symptoms such as pain, edema, suppuration, areas of bone sequestration, and limited mouth opening. Among the complications associated with this condition, pathological fracture may occur due to local bone fragility. This paper aimed to report a rare case of pathological mandible fracture due to osteomyelitis after third molar extraction in a healthy male patient treated by a surgical procedure. The procedure consisted of decortication and resection of the sclerotic bone followed by reduce and fixation of mandibular fracture with one 2.4 reconstructive plate and one 2.0 plate with standard screws.

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