scholarly journals Birth and Growth of Neuroimaging and Vascular Intervention at Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram—Part I

Author(s):  
Rajanikanth Rao Vedula ◽  
Ravi Mandalam Kolathu

AbstractThis article is a historical narrative that traces the growth of neuroradiology and interventional radiology at the Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram. From its humble origins in the pre-CT scan era of the mid and late 1970s, when invasive diagnostic procedures such as percutaneous carotid angiography, myelography, pneumoencephalography (PEG) and ventriculography were the mainstay of neuroimaging, the authors take the reader through their gradual foray into catheter four-vessel angiography and later free-flow embolization of arteriovenous malformations (AVMs), and finally to the use of microcatheters for selective embolization procedures. The equipment used in those early years—fluoroscopic tilting table, roll-film cameras, serial changers, PEG tables—provide an insight to an era with all its challenges before the advent of digital imaging. The authors’ efforts to indigenize some of the hardware such as metallic stents and embolization material such as hydrogel spheres and lyophilized dura are also highlighted. The development of peripheral vascular intervention alongside neuroradiology is also highlighted. The authors pay tribute to an early pioneer of neuroradiology in India, Prof. Mahadevan Pillai, who was a guiding light to them during those nascent years.

Author(s):  
Rajanikanth Rao Vedula ◽  
Ravi Mandalam Kolathu

AbstractThis is the second part of the two-part paper on the history of development of neuroradiology at the Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram. In this part, the authors describe the evolution of interventional procedures at their institute from the initial techniques of free-flow embolization as a palliative procedure for large arteriovenous malformations (AVMs) to the more refined techniques of selective embolization using microcatheters, calibrated leak balloons and liquid polymerizing embolic agents. The authors acknowledge the immense encouragement and support provided to them by the French neurointervention pioneers Prof. Luc Picard and Prof. Jacques Moret in this endeavor.


Author(s):  
Niveditta Ramkumar ◽  
Bjoern D Suckow ◽  
Jack L Cronenwett ◽  
Philip P Goodney

Introduction: While men and women are at equal risk for peripheral arterial disease (PAD), studies suggest that women present at an older age and with more advanced disease. The purpose of this analysis is to evaluate gender-based differences in disease presentation and its effect on treatment modality among patients who underwent peripheral vascular intervention (PVI) for PAD. Methods: Using national registry data from the Vascular Quality Initiative, univariate analysis, of patient-, limb- and artery-specific characteristics were performed by gender for procedures from 2010-2013. Statistical significance was determined by the Student’s T-test or Chi-squared test. Results: In this real-world cohort, there were 26,873 eligible procedures for 23,940 patients that had 30,668 limbs and 44,927 arteries treated. Compared to men, women presented at an older age (69 vs 71 years, p<0.001) and with more rest pain and tissue loss than claudication (RR=1.13, 95% CI: 1.10-1.16). Women had more severe lesions than men, as measured by TASC classification (TASC C or D RR= 1.81, 95% CI: 1.74-1.87) ( Table 1 ). There were no meaningful gender-based differences in artery treated or treatment modality ( Figure 1 ). Treatment modality was determined by disease severity (indication and TASC classification) and artery treated rather than gender. Conclusion: Although gender-based differences in PAD presentation exist, these differences do not extend to treatment modality, which is determined by disease severity and artery treated. Further investigation is required to appreciate the effect of disease severity and treatment modality on patient outcomes after PVI.


2021 ◽  
Vol 74 (4) ◽  
pp. e380
Author(s):  
Katherine E. Hawkins ◽  
R. James Valentine ◽  
Julie M. Duke ◽  
Amy B. Reed

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