scholarly journals Effect of Antibiotic Prophylaxis on Infectious Complications in Patients with Asymptomatic Bacteriuria Undergoing Urologic Surgery

2021 ◽  
Vol 30 (03) ◽  
pp. e157-e164
Author(s):  
Jorge A. Ramos-Castaneda ◽  
Alberto Ruano-Ravina ◽  
Javier Osorio-Manrique ◽  
Jackeline Barreto-Mora ◽  
Angela María Segura-Cardona ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Antibiotic Prophylaxis ◽  
Service Providers ◽  
Asymptomatic Bacteriuria ◽  
Infectious Complications ◽  
Prostatic Hyperplasia ◽  
Outcome Variable ◽  
Urologic Surgery ◽  
Health Service Providers ◽  
Surgical Antibiotic Prophylaxis

Abstract Objectives To identify the effect of duration of surgical antibiotic prophylaxis (SAP) and other variables on infectious postsurgical complications in patients with asymptomatic bacteriuria (ASB) undergoing urological surgery. Methods We conducted an observational study of a cohort of patients with ASB scheduled for urologic surgery at three health service providers in Colombia. The study population comprised all patients with planned urologic surgery who had ASB prior to surgery from April 2018 to January 2019. The intervention evaluated was the duration of preoperative SAP, and the outcome variable was the development of any postoperative infectious complications for up to 30 days after the procedure. Results The present study included 184 patients with ASB scheduled for urologic surgery.The median duration of preoperative SAP (p = 0.49) or of 1 dose SAP (risk ratio [RR] = 1.24; 95% confidence interval [CI]: 0.45–3.39) were not statistically different in patients with postsurgical infectious complications. Infectious complications were more frequent among patients with benign prostatic hyperplasia (RR = 6.57; 95%CI: 1.98–21.76) and hospitalization in the preceding 3 months (RR = 8.32; 95%CI: 2.69–25.71). Conclusion One dose of antimicrobial therapy is sufficient to avoid infectious complications in patients with ASB. There were other factors associated with postsurgical infectious complications, such as benign prostatic hyperplasia and hospitalization in the preceding 3 months.

scholarly journals MODERN METHODS OF ENDOSCOPIC ENUCLEATION OF BENIGN PROSTATIC HYPERPLASIA AND PROSPECTS FOR THEIR MODIFICATION

2021 ◽  
pp. 20-29
Author(s):  
E. N. Bolgov ◽  
F. A. Sevryukov ◽  
V. V. Zhezdrin ◽  
R. N. Bobrovsky ◽  
M. A. Volodin
Keyword(s):  
Surgical Treatment ◽  
Benign Prostatic Hyperplasia ◽  
Laser Energy ◽  
Low Frequency ◽  
Complete Removal ◽  
Infectious Complications ◽  
Prostatic Hyperplasia ◽  
Anatomical Landmarks ◽  
Surgical Methods ◽  
Endoscopic Enucleation

The disadvantage of bipolar and holmium enucleation in transurethral surgery of benign prostatic hyperplasia (BPH) is the frequent postoperative urination disorders. To increase the effectiveness of surgical treatment, a modification of the surgical technique is necessary.Objective: to compare the perioperative results of endosurgical treatment of large sized BPH using transurethral bipolar (TUEB), laser (HoLEP) and modified laser prostate enucleation (HoLEP-M) methods. Patients and methods: A randomized prospective study was conducted according to the results of surgical treatment of 1104 patients with BPH with a volume of 80 to 350 cm3, divided by methods of endoscopic enucleation of the prostate. A mod-ification of the HoLEP technique was to optimize access to the surgical site with the designation of new anatomical landmarks.Results: Comparison of surgical methods showed their equivalence in the volume of removed tissue, the low frequency of hemorrhagic and infectious complications, the dynamics of urological indicators in the delayed period. TUEB has the least parameters for the time of surgical intervention (98.2 ± 2.24 min.), the vol-ume of blood loss (65.5 ± 1.83 ml), the terms of postoperative catheterization of the bladder (2.0 ± 0.32 days), and the days of hospitalization (3.2 ± 0.40 days). The safety of laser methods is higher than TUEB, during which 3.1% of closed perforations of the prostatic capsule and bladder were observed (versus 0.8-1.5% with laser methods). Modification of the HoLEP technique allows reducing the frequency of late dysuric disorders by 2-3 times, urinary incontinence by 3.4-4 times, cicatricial complications by 1.7-2 times.Conclusion: Bipolar and laser methods of transurethral enucleation of the prostate of large sizes are comparable by criteria of complete removal of prostatic tissue, effectiveness and tolerability in patients with thrombohemorrhagic risk. In terms of the frequency of intraoperative injuries, the safety of laser methods is higher due to the reduced penetrating ability of laser energy. Modification of surgical access to the prostate preserves the prostatic urethra as much as possible and is a promising measure for the prevention of late obstructive and functional complications of transurethral interventions.

Duration of surgical antibiotic prophylaxis in patients with asymptomatic bacteriuria – Authors' reply

2017 ◽  
Vol 17 (4) ◽  
pp. 370-371
Author(s):  
Benedetta Allegranzi ◽  
Leonardo Pagani ◽  
Stijn de Jonge ◽  
Marja A Boermeester ◽  
Didier Pittet
Keyword(s):  
Antibiotic Prophylaxis ◽  
Asymptomatic Bacteriuria ◽  
Surgical Antibiotic Prophylaxis

scholarly journals The Effect of Seoritae Extract in Men with Mild to Moderate Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Woong Jin Bae ◽  
Hyo Jung Park ◽  
Hye Cheong Koo ◽  
Do Ram Kim ◽  
U-Syn Ha ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Benign Prostatic Hyperplasia ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Specific Antigen ◽  
Prostatic Hyperplasia ◽  
Outcome Variable ◽  
International Prostatic Symptom Score ◽  
Urinary Tract Symptoms ◽  
Lower Urinary

We evaluated the effects of Seoritae extract (SE) on mild to moderate lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). Seventy-six subjects with mild to moderate LUTS suggestive of BPH were prospectively recruited from the urology outpatient clinic and assigned to either SE (4200 mg or 6 tablets 3 times a day) or matching placebo. The primary outcome variable, the International Prostatic Symptom Score (IPSS), was evaluated at baseline and at 4 and 12 weeks. Postvoid residual volume (PVR), maximum urine flow rate (Qmax), and prostate-specific antigen (PSA) levels were evaluated. IPSSs decreased significantly from baseline to 12 weeks within the SE group. Significant improvements in IPSS voiding scores at 4 and 12 weeks were also observed in the SE group compared to the placebo group. IPSS storage and quality of life scores were also significantly decreased at 12 weeks in the SE group. There was no change inQmaxor PVR in both groups after 12 weeks. Administration of SE for 12 weeks led to significant improvements in LUTS, and it can be concerned as a reasonable and safe alternative for men with mild to moderate LUTS.

scholarly journals Pharmacokinetic peculiarities of intravenous and oral ciprofloxacin administration in preoperative prophylaxis in patients with benign prostatic hyperplasia

2014 ◽  
Vol 12 (4) ◽  
pp. 64-66
Author(s):  
Igor Vladimirovich Sosin ◽  
Vladimir Vitalevich Rafalskiy ◽  
Petr Dmitriyevich Shabanov
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Oral Administration ◽  
Antibiotic Prophylaxis ◽  
Population Pharmacokinetics ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Preoperative Antibiotic Prophylaxis ◽  
Oral Ciprofloxacin ◽  
Preoperative Prophylaxis

The study of population pharmacokinetics of ciprofloxacin at various ways of administration helps to found that the once usage of 500 mg ciprofloxacin orally 90-120 min before the surgery as preoperative antibiotic prophylaxis with transurethral resection of the prostate gland creates a significantly higher concentration of the drug in blood, urine and prostate parenchyma compared to intravenously administration of 400 mg ciprofloxacin 30-60 min before operation. Thus, the data obtained explain the higher efficacy of oral administration of ciprofloxacin as preoperative antibiotic prophylaxis in patients undergoing transurethral resection of the prostate.

1438: Benign Prostatic Hyperplasia Outcomes 12 Months after Initiating Medical Management: An Analysis of Managed Care Data

2006 ◽  
Vol 175 (4S) ◽  
pp. 464-465
Author(s):  
Michael J. Naslund ◽  
Muta M. Issa ◽  
Libby Black ◽  
Michael Eaddy ◽  
Manan Shah
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Managed Care ◽  
Medical Management ◽  
Prostatic Hyperplasia
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