scholarly journals Pharmacokinetic peculiarities of intravenous and oral ciprofloxacin administration in preoperative prophylaxis in patients with benign prostatic hyperplasia

2014 ◽  
Vol 12 (4) ◽  
pp. 64-66
Author(s):  
Igor Vladimirovich Sosin ◽  
Vladimir Vitalevich Rafalskiy ◽  
Petr Dmitriyevich Shabanov
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Oral Administration ◽  
Antibiotic Prophylaxis ◽  
Population Pharmacokinetics ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Preoperative Antibiotic Prophylaxis ◽  
Oral Ciprofloxacin ◽  
Preoperative Prophylaxis

The study of population pharmacokinetics of ciprofloxacin at various ways of administration helps to found that the once usage of 500 mg ciprofloxacin orally 90-120 min before the surgery as preoperative antibiotic prophylaxis with transurethral resection of the prostate gland creates a significantly higher concentration of the drug in blood, urine and prostate parenchyma compared to intravenously administration of 400 mg ciprofloxacin 30-60 min before operation. Thus, the data obtained explain the higher efficacy of oral administration of ciprofloxacin as preoperative antibiotic prophylaxis in patients undergoing transurethral resection of the prostate.

scholarly journals 250 Gambaran Benigna Prostat Hiperplasia di RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2014 – Juli 2017

e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Filzha Adelia ◽  
Alwin Monoarfa ◽  
Angelica Wagiu
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Descriptive Study ◽  
Prostatic Hyperplasia ◽  
Transurethral Resection Of Prostate ◽  
Age Group ◽  
Flow Disturbance ◽  
Main Complaint ◽  
Common Action

Abstract: Benign prostatic hyperplasia (BPH) is defined as stromal cell proliferation of prostate gland which causes enlargement of the gland. It manifests as urine flow disturbance, difficult to urinate, and desire to urinate, however, the urine emission is low. In 2013, Indonesia has 9.2 million cases of BPH among men aged over 60 years. This study was aimed to obtain the profile of BPH cases at Prof. Dr. R. D. Kandou Hospital Manado in the period of January 2014 to June 2017. This was a retrospective descriptive study at Medical Record Installation of Prof. Dr. R. D. Kandou Hospital. The results showed that during that period of time, the highest percentage of cases was in 2016 (38.46%) and the most common age group was 61-70 years old (46.15%). The main complaint among the patients was difficult to urinate and the most frequently performed action was transurethral resection of prostate (TURP) (51.28%). Conclusion: In this study, BPH cases were most common at the age group 61-70 years old. Moreover, TURP was the most common action performed.Keywords: benign prostatic hyperplasia Abstrak: Benigna prostat hiperplasia (BPH) didefinisikan sebagai proliferasi dari sel stromal pada prostat, yang menyebabkan pembesaran kelenjar tersebut. Manifestasi BPH dapat berupa terganggunya aliran urin, sulit buang air kecil (BAK), dan keinginan buang air kecil namun pancaran urin lemah. Pada tahun 2013 di Indonesia terdapat 9,2juta kasus BPH, umumnya diderita laki-laki berusia di atas 60 tahun. Penelitian ini bertujuan untuk mendapatkan gambaran kasus BPH di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2014 – Juli 2017. Jenis penelitian ialah deskriptif retrospektif , yang dilakukan di Instalasi Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian menunjukkan bahwa jumlah kasus BPH tertinggi pada tahun 2016 (38,46%) dan pada kelompok usia 61-70 tahun (46,15%). Keluhan utama semua pasien ialah sulit BAK. Tindakan yang paling sering digunakan yaitu transurethral resection of prostate (TURP) (51,28%). Simpulan: Kasus BPH terutama ditemukan berusia 61-70 tahun. Tindakan yang paling sering dilakukan yaitu reseksi prostat transuretra (TURP).Kata kunci: benigna prostat hiperplasia

scholarly journals Scoping Review: Pengaruh Terapi TURP terhadap Benign Prostatic Hyperplasia pada Lansia

2021 ◽  
Vol 3 (1) ◽  
pp. 59-64
Author(s):  
Dito Dewantoro Satriawan ◽  
Diana Wijayanti ◽  
Meta Maulida Damayanti
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Scoping Review ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
The Elderly ◽  
Prostatic Hyperplasia ◽  
Flow Chart ◽  
Research Articles ◽  
Original Research ◽  
Transurethral Resection Of Prostate

Benign prostatic hyperplasia (BPH) merupakan istilah histopatologis, yaitu hiperplasia sel stroma dan sel epitel kelenjar prostat,dan bersifat jinak. Prevalensi BPH terjadi sekitar 70% pada pria di atas usia 60 tahun. Tujuan terapi pada pasien BPH adalah memperbaiki kualitas hidup pasien. Salah satu pilihan terapi untuk BPH yaitu transurethral resection of prostate (TURP) yang merupakan metode paling banyak digunakan untuk mengatasi pembesaran prostat. Tujuan penelitian ini adalah melihat gambaran pengaruh terapi TURP terhadap BPH pada lansia. Penelitian ini merupakan Scoping Review, yang diambil dari database PubMed, Springer Link, dan Science Direct dengan metode original research articles (observasional). Penelitian ini dinilai secara PICOS untuk ditentukan sebagai kriteria eligible pada prisma flow chart yang sesuai yaitu population (pasien BPH, lansia), intervention (terapi TURP), comparison (terapi lain), outcome (kesembuhan pasien BPH) terdapat 10.025 artikel, dan hasil uji berdasar atas PICOS sebanyak 10 artikel. Hasil analisis dan review dari 10 artikel ini, yaitu terapi TURP memiliki banyak fungsi serta manfaat untuk perbaikan kondisi pasien. Indikator tersebut dapat dinilai dari penurunan risiko perdarahan, waktu operasi, waktu irigasi kandung kemih, durasi kateterisasi, durasi rawat inap, perbaikan pada IPSS, QoL, Qmax, PVR, Na+ serum, K+ serum, kadar hematokrit, volume cairan irigasi, kadar hemoglobin, kreatinin serum, volume prostat dasar, IIEF-5, CTCAE, SHIM, MSHQ-EjD, dan ISI. Pasien BPH juga dapat mengalami risiko komplikasi intraoperatif ataupun pascaoperatif. Kesimpulan penelitian ini menunjukkan bahwa pengaruh terapi TURP terhadap BPH pada lansia mempunyai hasil yang cukup baik, efisien, dan efektif. Scoping Review: the Effect of TURP Therapy on Benign Prostatic Hyperplasia in the ElderlyBenign prostatic hyperplasia (BPH) is a histopathological term, which is hyperplasia of stromal cells and epithelial cells of the prostate gland, and is benign. The prevalence of BPH occurs in about 70% in men over the age of 60. The goal of therapy in BPH patients is to improve the patient's quality of life. One of the treatment options for BPH is the transurethral resection of prostate (TURP) which is the most widely used method to treat an enlarged prostate. The purpose of this study was to describe the effect of TURP therapy on BPH in the elderly. This research is a Scoping Review, which is taken from the PubMed, Springer Link, and Science Direct databases using the original research articles (observational) method. This study was assessed by PICOS to be determined as eligible criteria on the appropriate prism flow chart, namely population (BPH patients, the elderly), intervention (TURP therapy), comparison (other therapies), 10,025 articles of outcome (recovery of BPH patients), and test results. based on PICOS as many as 10 articles. The results of the analysis and review of these 10 articles are: TURP therapy has many functions and benefits for improving the patient's condition. These indicators can be assessed from the decreased risk of bleeding, time of operation, time of bladder irrigation, duration of catheterization, duration of hospitalization, improvement in IPSS, QoL, Qmax, PVR, serum Na +, serum K +, levels of hematocrit, volume of irrigation fluid, hemoglobin levels, serum creatinine, baseline prostate volume, IIEF-5, CTCAE, SHIM, MSHQ-EjD, and ISI. Patients with BPH may also be at risk of intraoperative or postoperative complications. The conclusion of this study shows that the effect of TURP therapy on BPH in the elderly has good, efficient and effective results.

LASER TECHNOLOGIES IN SURGERY BENEFICIAL PROSTATE HYPERPLASIA

2021 ◽  
pp. 144-153
Author(s):  
Rakhimov S.A. ◽  
Feofilov I.V. ◽  
Arbuzov I.A.
Keyword(s):  
Surgical Treatment ◽  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Prostate Hyperplasia ◽  
Advantages And Disadvantages ◽  
Laser Technologies ◽  
Surgical Methods ◽  
Laser Systems

Benign prostatic hyperplasia is one of the most common diseases in urological practice. The classical method of surgical treatment of benign prostatic hyperplasia is transurethral resection of the prostate gland. However, this operation is accompanied by a fairly large number of postoperative complications and is not recommended for patients with a large prostate volume, with a high cardiovascular risk, and receiving anticoagulant therapy. In recent years, the medical community has been paying close attention to laser technologies. The article provides an overview of the literature on laser methods for the treatment of benign prostatic hyperplasia. Modern laser systems are considered: holmium, thulium, diode, «green» lasers. The advantages and disadvantages of each technique are described. The results of studies of the efficacy and safety of laser surgical methods for the treatment of benign prostatic hyperplasia and their influence on the indicators of urodynamics, symptoms of the disease, and the quality of life of patients are presented. Based on the analysis of scientific literature sources, it was concluded that laser methods of surgical treatment of benign prostatic hyperplasia are clinically effective and safe. Compared with transurethral resection of the prostate, laser technologies can shorten the period of hospitalization and catheterization of patients, have a low number of complications, provide good hemostasis, and can be used regardless of the volume of the gland in patients with concomitant diseases who are taking anticoagulants. Laser methods of surgical treatment of benign prostatic hyperplasia are currently a full-fledged worthy alternative to transurethral resection of the prostate gland. Among the disadvantages of using laser systems are the duration of the operation and the need to train specialists in the technique of surgical intervention.

scholarly journals Cost analysis of Greenlight photoselective vaporization of the prostate compared to transurethral resection of the prostate for benign prostatic hyperplasia

2018 ◽  
Vol 12 (12) ◽  
Author(s):  
Lisa Masucci ◽  
Aysegul Erman ◽  
Murray D. Krahn ◽  
Dean Elterman
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Linear Regression ◽  
Transurethral Resection ◽  
Charlson Comorbidity Index ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Academic Medical Centre ◽  
Total Cost ◽  
Photoselective Vaporization ◽  
Comorbidity Index

Introduction: Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland, which results in the development of lower urinary tract symptoms that can interfere with patients’ daily activities and negatively impact their quality of life. The gold standard treatment for moderate to severe BPH has been transurethral resection of the prostate (TURP), however, this procedure is associated with prolonged hospitalizations and increased complications. An alternative to TURP is Greenlight photoselective vaporization of the prostate (PVP), which is associated with better perioperative safety. The objectives of the research were to: 1) assess the cost of Greenlight PVP compared to TURP and bipolar TURP; and 2) assess the predictors of total cost. Methods: We conducted a descriptive costing study from the hospital perspective. We evaluated perioperative costs of patients who underwent each procedure from 2013–2015 at a tertiary academic medical centre. A multiple linear regression was performed to identify predictors of total cost. The variables included in regression analysis were patient age, type of procedure, Charlson Comorbidity Index, and distance to clinic. Results: A total of 202 patients received one of the three procedures over the study period. The total cost of Greenlight PVP was $3836 per patient compared to $4963 for TURP and $4978 for bipolar TURP. The linear regression showed that the Charlson Comorbidity Index and type of procedure were independent predictors of total cost. Conclusions: The procedure costs and readmission rates are lower for Greenlight PVP compared to TURP and bipolar TURP, making it a preferable option for hospitals.

scholarly journals Outcomes of Transurethral Resection of the Prostate in Benign Prostatic Hyperplasia Comparing Prostate Size of more than 80 Grams to Prostate Size less than 80 Grams

2015 ◽  
Vol 12 (3) ◽  
pp. 163-167 ◽  
Author(s):  
HN Joshi ◽  
IJ De Jong ◽  
RM Karmacharya ◽  
B Shrestha ◽  
R Shrestha
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Transurethral Resection Of Prostate ◽  
Prostate Size ◽  
The Mean ◽  
Group 2 ◽  
Large Prostate ◽  
Group 1

Background Benign prostatic hyperplasia is a condition occurring in elderly men in which the prostate gland is enlarged, hence the condition also known as benign enlargement of prostate. Benign hyperplasia can lead to both obstructive and irritative symptoms. Transurethral resection of prostate (TURP) still remains the gold standard modality of surgical treatment of obstructive lower urinary tract symptoms due to Benign hyperplasia.Objectives The objective of this study was to evaluate the outcomes of TURP in large prostate (>80 grams) in comparison to small prostate (<80 grams) in terms of efficacy, safety and complications.Methods A total of 65 cases included in this prospective study, which were operated by a single surgeon with conventional monopolar TURP using standard technique. Intra -operative and post-operative complications, pre and post- operative quality of life (QoL) and international prostate symptom score (IPSS), operative time, time to removal of catheter and hospital stay were evaluated between small and large prostate gland volumes.Results Out of 65 cases, 30 were with large prostate size i.e. 80 grams or more (group 1), and 35 cases were with small prostate size than 80 grams size (group 2). Mean age was 71.8 SD ± 6.9 years in group 1 and 68.2 SD ± 12.7 years in group 2. The mean preoperative volume of prostate was 88.8 grams (range 80-115 grams) in group 1 and 40.3 (range 20-65 grams) in group 2. The mean preoperative post void residual volume of urine (PVRU) was 244 ml SD ± 190.8 ml in group 1 and 117 ml ± 70.3 ml in group 2. Mean resection time in group 1 was 110 (range 90-130) minutes and in group 2 it was 90 minutes (range 55-115) minutes. There were quite satisfactory improvements in IPSS and QoL. No significant complications were observed except TUR syndrome in 2 cases from group 2, which were managed well in postoperative period.Conclusion With meticulous resection and intra-operative haemostasis using continuous out flow resectoscope, conventional monopolar TURP is equally safe and effective in large size prostate as compare in small size.Kathmandu University Medical Journal Vol.12(3) 2014; 163-167

scholarly journals HUBUNGAN KECEMASAN DENGAN KUALITAS TIDUR PADA PASIEN PRE OPERASI TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN

2021 ◽  
Vol 4 (2) ◽  
pp. 491-498
Author(s):  
Christine Handayani Siburian
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Sleep Quality ◽  
Transurethral Resection ◽  
Quality Index ◽  
Pittsburgh Sleep Quality Index ◽  
Prostate Gland ◽  
Sampling Technique ◽  
Prostatic Hyperplasia ◽  
Medical Procedure ◽  
Cross Sectional

Benign Prostatic Hyperplasia (BPH) is an enlargement of the prostate gland that generally occurs in older men and if left untreated can lead to complications. BPH can be treated with a medical procedure, namely the Transurethral Resection of the Prostate (TURP) surgical procedure. Before the action, the patient will experience anxiety. Anxiety arises because of excessive fear that can affect the quality of sleep. The purpose of this study was to determine the relationship between anxiety and sleep quality in patients with preoperative Transurethral Resection of the Prostate (TURP). The research design used was cross sectional. The sample is 31 respondents of preoperative patients at Rumah Sakit Umum Imelda Pekerja Indonesia Medan with the sampling technique used is accidental sampling. The research data was collected using the Hamilton Scale for Anxiety (HRS-A) questionnaire and The Pittsburgh Sleep Quality Index (PSQI) questionnaire. Data were analyzed by Spearman Rho correlation test. The results showed that there was a relationship between anxiety and sleep quality in patients with preoperative Transurethral Resection of the Prostate (TURP) (p=0.000, r=0.907). The results of this study can recommend that the need for nursing actions that can reduce anxiety so that the patient's sleep quality can be better.   Abstrak Benign Prostatic Hyperplasia (BPH) adalah pembesaran kelenjar prostat yang pada umumnya terjadi pada pria yang lebih tua dan apabila tidak diobati dapat menyebabkan komplikasi. BPH dapat ditangani dengan tindakan medis yaitu prosedur pembedahan Transurethral Resection of the Prostate (TURP). Sebelum dilakukan tindakan tersebut, pasien akan mengalami kecemasan. Kecemasan timbul karena rasa takut berlebih yang dapat mempengaruhi kualitas tidur. Tujuan penelitian ini adalah mengetahui hubungan kecemasan dengan kualitas tidur pada pasien pre operasi Transurethral Resection of the Prostate (TURP). Desain penelitian yang digunakan Cross Sectional. Sampel adalah 31 responden pasien pre operasi di Rumah Sakit Umum Imelda Pekerja Indonesia Medan dengan teknik pengambilan sampel adalah teknik accidental sampling. Pengumpulan data penelitian menggunakan kuesioner Hamilton Scale for Anxiety (HRS-A) dan kuesioner The Pittsburgh Sleep Quality Index (PSQI). Data dianalisis dengan uji korelasi Spearman Rho. Hasil didapatkan ada hubungan kecemasan dengan kualitas tidur pada pasien pre operasi Transurethral Resection of the Prostate (TURP) (p=0,000, r=0,907). Hasil penelitian ini dapat merekomendasikan bahwa perlunya tindakan keperawatan yang dapat mengurangi kecemasan agar kualitas tidur pasien dapat menjadi lebih baik.

Evaluation of mid-term results of bipolar transurethral resection in the treatment of benign prostatic hyperplasia

2018 ◽  
pp. 1-9
Author(s):  
А.С. Векильян
Keyword(s):  
Surgical Treatment ◽  
Benign Prostatic Hyperplasia ◽  
Blood Loss ◽  
Endoscopic Surgery ◽  
Transurethral Resection ◽  
Operating Time ◽  
Clinical Results ◽  
Massive Bleeding ◽  
Prostatic Hyperplasia ◽  
Surgical Methods

Представлены клинические результаты хирургического лечения доброкачественной гиперплазии предстательной железы (ДГПЖ) объемом до 100 см3 методом биполярной трансуретральной резекции простаты (БТУР -74 пациента) в сравнении с открытой чреспузырной простатэктомией (ОПЭ - 96 пациентов), ранее применявшейся для подобных клинических случаев в урологической клинике "Железнодорожной больницы" г. Волгоград. При статистически равном операционном времени обоих хирургических методов для БТУР отмечено существенное снижение интраоперационной кровопотери, сроков послеоперационной катетеризации и пребывания в стационаре, минимальная частота геморрагических и инфекционно-воспалительных осложнений. Наблюдение за урологическим статусом пациентов в течение первого послеоперационного года показало одинаковую клиническую эффективность сравниваемых хирургических методов. Значительное снижение объема кровопотери в ходе операции БТУР можно считать большим достижением, поскольку улучшение видимости в зоне хирургического вмешательства позволяет оптимизировать гемостаз, предотвратить массивные кровотечения как во время, так и после операции, сократить сроки послеоперационной катетеризации мочевого пузыря, что в свою очередь, снижает частоту развития инфекционно-воспалительных осложнений. Более быстрое восстановление пациентов после эндоскопических операций имеет медико-социальное и экономическое значение, поскольку минимальное количество послеоперационных осложнений и сокращение сроков госпитализации позволяет существенно снизить затраты на лечение и быстрее нормализовать качество жизни пациентов. Полученные результаты демонстрируют перспективность внедрения биполярных методов эндоскопических операций для лечения ДГПЖ в хирургическую практику урологических стационаров в целях повышения безопасности оперативного лечения и экономии затрат на госпитализацию. The clinical results of surgical treatment of benign prostatic hyperplasia (BPH) up to 100 cm3 by bipolar transurethral resection of the prostate (BTUR - 74 patients) in comparison with open transvesical prostatectomy (OPE - 96 patients), previously used for such clinical cases in the urological clinic "Railway hospital" in Volgograd are presented. With statistically equal operating time of both surgical methods, there was a significant decrease in intraoperative blood loss, the terms of postoperative catheterization and hospital stay, the minimum frequency of hemorrhagic and infectious-inflammatory complications. Observation of the urological status of patients during the first postoperative year showed the same clinical efficacy of the compared surgical methods. A significant reduction in the volume of blood loss during the operation, can be considered a great achievement, since the improvement of visibility in the area of surgical intervention allows to optimize the hemostasis, to prevent massive bleeding during and after surgery, to reduce the duration of postoperative bladder catheterization, which, in turn, reduces the incidence of infectious-inflammatory complications. Faster recovery of patients after endoscopic surgery of medical,social and economic importance, as the minimum number of postoperative complications and reduction of hospitalization can significantly reduce the cost of treatment and quickly normalize the quality of life of patients. The results demonstrate the prospects of the introduction of bipolar methods of endoscopic surgery for the treatment of BPH in the surgical practice of urological hospitals in order to improve the safety of surgical treatment and save costs for hospitalization.

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