Extradural Peripheral Nerve Sheath Tumour at T7 Level in a 2-Year-Old Dog

AbstractThe aim of this report is to describe an unusual localization of nerve sheath tumour (NST), clinical presentation, imaging, surgical management, and outcome in a 2-year-old dog. A 2-year-old female American Staffordshire Terrier presented with nonambulatory paraparesis, thoracolumbar hyperaesthesia, hindlimb hyperreflexia, and mild muscle atrophy. Computed tomography and magnetic resonance imaging revealed an extradural mass at T7-T8, without vertebral lesions. Surgical treatment consisted in resection of the soft tissue mass through dorsal laminectomy. The dog was ambulatory within 24 hours and free of recurrence at 18 months postoperatively. Histopathologic and features of immunohistochemistry were consistent with NST. The NST of this report was similar to those described before, but exhibited unusual characteristics, such as being extradural, without extension into intervertebral foramina, and being located in an atypical region (T7-T8). Moreover, survival time and relapse-free interval are greater than previously reported for similar cases.

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Metastatic melanoma presenting as a malignant peripheral nerve sheath tumour

Journal of Dermatology & Cosmetology ◽

10.15406/jdc.2021.05.00172 ◽

2021 ◽

Vol 5 (1) ◽

pp. 1-4

Author(s):

David John Mackay Smith

Keyword(s):

Peripheral Nerve ◽

Metastatic Melanoma ◽

Spindle Cell ◽

Correct Diagnosis ◽

Primary Cutaneous Melanoma ◽

Tissue Mass ◽

Nerve Sheath Tumour ◽

Nerve Sheath ◽

Spindle Cell Proliferation ◽

Peripheral Nerve Sheath Tumour

This is a report of a metastatic melanoma presenting clinically as a soft tissue mass and histologically being diagnosed as a malignant peripheral nerve sheath tumour. In this case the metastatic melanoma was preceded by a primary cutaneous melanoma in a similar anatomical region. Histologically the tumour was characterised by a malignant-appearing Spindle cell proliferation, arranged in fascicules. There was no evidence of connection to a nerve, co-existent neurofibroma or stigmata of neurofibromatosis. This presentation is only infrequently mentioned in the literature and heterogeneity can make clinical and histological diagnosis of metastatic melanoma problematic. It can easily be misinterpreted without effective clinico-histological correlation, making a good working relationship between Clinician and Histopathologist essential for correct diagnosis.

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Magnetic resonance imaging features of a benign peripheral nerve sheath tumour with ‘ancient’ changes in the tongue of a horse

Equine Veterinary Education ◽

10.1111/j.2042-3292.2010.00088.x ◽

2010 ◽

Vol 22 (7) ◽

pp. 346-351 ◽

Cited By ~ 12

Author(s):

A. Schneider ◽

C. Tessier ◽

D. Gorgas ◽

P. Kircher ◽

J. Mamani ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Peripheral Nerve ◽

Imaging Features ◽

Resonance Imaging ◽

Nerve Sheath Tumour ◽

Nerve Sheath ◽

Peripheral Nerve Sheath Tumour

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Malignant peripheral nerve sheath tumour in the submandibular space

Annals of The Royal College of Surgeons of England ◽

10.1308/rcsann.2017.0060 ◽

2017 ◽

Vol 99 (5) ◽

pp. e137-e138 ◽

Cited By ~ 1

Author(s):

JB Olivier

Keyword(s):

Soft Tissue ◽

Peripheral Nerve ◽

Adjuvant Radiotherapy ◽

Soft Tissue Mass ◽

Tissue Mass ◽

Complete Excision ◽

Aggressive Form ◽

Nerve Sheath ◽

Anatomical Area ◽

Peripheral Nerve Sheath Tumour

Malignant peripheral nerve sheath tumours (MPNSTs) are a rare but aggressive form of soft tissue sarcoma with few reported cases in the anatomic location seen with the case presented here. This case involves a 23-year-old man presenting with a soft tissue mass under the mandible found to be a MPNST, which was investigated and fully excised. Adjuvant radiotherapy was used postoperatively. Although uncommon, these tumours have a poor prognosis and suitable management therefore needs to be put in place as soon as possible. Complete excision with negative margins and adjuvant radiotherapy are the current methods used for treatment. This case is unusual and highlights the management of an aggressive tumour in a difficult anatomical area, prompting the consideration of MPNST as a differential diagnosis for a soft tissue mass.

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Malignant tumours as a rare cause of recurrent thrombophlebitis of the great saphenous vein

Phlebologie ◽

10.1055/s-0037-1622244 ◽

2008 ◽

Vol 37 (06) ◽

pp. 297-300

Author(s):

N. König ◽

H. J. Stark ◽

P.-M. Baier

Keyword(s):

Differential Diagnosis ◽

Saphenous Vein ◽

Great Saphenous Vein ◽

Case Reports ◽

Malignant Tumours ◽

Nerve Sheath Tumour ◽

Below The Knee ◽

Nerve Sheath ◽

Unfavourable Prognosis ◽

Peripheral Nerve Sheath Tumour

SummaryWe present two case reports concerning patients who had to undergone surgical treatment according tp the diagnosis of thrombophlebitis with insufficiency of the greater saphenous vein and putative encapsulated haematoma in the lower left leg area. During the operation we found tumours with urgent suspicion of malignancy. The histological examination revealed the diagnosis of mesenchymal chondrosarcoma and malignant peripheral nerve sheath tumour which are extremely malignant, but very rare neoplasmas with unfavourable prognosis. Conclusion: Since both types of tumours are often located below the knee, phlebotomists and vascular surgeons should take them into account as differential diagnosis.

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