scholarly journals Combinatorial Chemistry - From Theory to Application (Methods and Principles in Medicinal Chemistry, Vol. 26)

Synthesis ◽  
2006 ◽  
Vol 2006 (19) ◽  
pp. 3348-3348
Author(s):  
Rolf Breinbauer
Keyword(s):  
Combinatorial Chemistry ◽  
Medicinal Chemistry ◽  
Application Methods

Natural products from Brazilian biodiversity as a source of new models for medicinal chemistry

2012 ◽  
Vol 84 (9) ◽  
pp. 1837-1846 ◽  
Author(s):  
Vanderlan da Silva Bolzani ◽  
Marilia Valli ◽  
Marcos Pivatto ◽  
Cláudio Viegas
Keyword(s):  
Natural Products ◽  
Combinatorial Chemistry ◽  
Medicinal Chemistry ◽  
Therapeutic Agents ◽  
Molecular Structures ◽  
Biologically Active ◽  
Ache Inhibitors ◽  
Tropical Environments ◽  
Modern Drug ◽  
Brazilian Biodiversity

Natural products are the inspiration for many valuable therapeutic agents and attest to biodiversity being a rich source of new molecular structures. Their value as templates for medicinal chemistry remains undisputed, even after the growth of the combinatorial chemistry era. Tropical environments, such as Brazilian biomes, offer a particularly rich potential for biologically active compounds with unique structures and continue to contribute toward modern drug discovery. Our bioprospecting of plant species of the Cerrado and Atlantic Forest biomes has yielded promising bioactive secondary metabolites, and we describe some of these molecules and semisynthetic derivatives as potential acetylcholinesterase (AChE) inhibitors.

scholarly journals Bio-instructive materials on-demand – combinatorial chemistry of peptoids, foldamers, and beyond

2021 ◽  
Author(s):  
Claudine Herlan ◽  
Dominik Feser ◽  
Ute Schepers ◽  
Stefan Bräse
Keyword(s):  
High Throughput ◽  
Combinatorial Chemistry ◽  
Medicinal Chemistry ◽  
Materials Science ◽  
Modular Design ◽  
Rapid Synthesis ◽  
On Demand ◽  
Compound Libraries ◽  
Large Compound

Combinatorial chemistry allows for the rapid synthesis of large compound libraries for high throughput screenings in biology, medicinal chemistry, or materials science. Especially compounds from a highly modular design are...

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