A Reconstruction Method Using Musculopericranial Flaps that Prevents Cerebrospinal Fluid Rhinorrhea and Intracranial Complications after Extended Anterior Skull Base Resection

Cerebrospinal fluid rhinorrhea is a serious and potentially fatal condition because of an increased risk of meningitis and brain abscess. Approximately 80% of all cases occur in patients with head injuries and craniofacial fractures. Despite technical advances in the diagnosis and management of CSF rhinorrhea caused by craniofacial injury through the introduction of MRI and endoscopic extracranial surgical approaches, difficulties remain. The authors review here the pathophysiology, diagnosis, and management of CSF rhinorrhea relevant exclusively to traumatic anterior skull base injuries and attempt to identify areas in which further work is needed.

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Clinical case of multiple minor defect on anterior skull base and role of usage the fluorescein intrathecal in detection of cerebrospinal fluid rhinorrhea

10.1055/s-0039-1686763 ◽

2019 ◽

Author(s):

A Topalova ◽

K Dzhambazov ◽

G Pavlov ◽

S Konsulov ◽

N Dzhambazova-Trajkova

Keyword(s):

Cerebrospinal Fluid ◽

Skull Base ◽

Clinical Case ◽

Anterior Skull Base ◽

Cerebrospinal Fluid Rhinorrhea

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Use of Dental Bisphenol A-Glycidyl Methacrylate Composite to Repair Refractory Cerebrospinal Fluid Leaks Associated With Large-Scale Anterior Skull Base Defects

Journal of Craniofacial Surgery ◽

10.1097/scs.0000000000007568 ◽

2021 ◽

Vol Publish Ahead of Print ◽

Author(s):

Djientcheu Vincent de Paul ◽

Casimir Fankem ◽

Dia R. Halalmeh ◽

Ewo Clement ◽

Aubin Sandio ◽

...

Keyword(s):

Cerebrospinal Fluid ◽

Bisphenol A ◽

Skull Base ◽

Glycidyl Methacrylate ◽

Large Scale ◽

Anterior Skull Base ◽

Cerebrospinal Fluid Leaks ◽

Skull Base Defects

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Bilateral Choanal Atresia Associated with Malformation of the Anterior Skull Base: Embryogenesis and Clinical Implications

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949210101106 ◽

1992 ◽

Vol 101 (11) ◽

pp. 916-919 ◽

Cited By ~ 16

Author(s):

Michael E. Dunham ◽

Robert P. Miller

Keyword(s):

Skull Base ◽

Choanal Atresia ◽

Three Dimensional ◽

Anterior Skull Base ◽

Preoperative Imaging ◽

Clinical Implications ◽

High Resolution Computed Tomography ◽

Ethmoid Bone ◽

Intracranial Complications ◽

Skull Base Defect

A number of craniofacial and systemic malformations have been described in association with choanal atresia. We report a case of bilateral choanal atresia associated with congenital absence of the cribriform plate, crista galli, and perpendicular plate of the ethmoid bone. The anterior skull base defect was detected by using high-resolution computed tomography with three-dimensional reconstructions. The findings support the mesodermal flow theory of choanal atresia, in which there is excess migration of neural crest cells into the developing nasal septum and posterior choanae. This occurs at the expense of cells that would otherwise form the rest of the ethmoid complex. Clinical implications include the need for adequate preoperative imaging of the anterior skull base and consideration of potential intracranial complications during surgical repair.

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