The Challenge of Regulation, Globalization and Climate Change on Botanicals and Traditional Medicines: Respecting Tradition While Embracing Change

INDIA – Climate change threatens India’s native plants. INDIA – Air pollution hits crops more than climate change. LAOS – Laos targets green energy in new Asian economic bloc. THE PHILIPPINES – Centuries-old traditional medicines still used in Palau. SINGAPORE – MerLion’s finafloxacin shows positive phase 2 results in complicated urinary tract infections. AFRICA – Biosciences research ‘key but gets small local support’. AFRICA – Biofortified maize ‘could control vitamin A deficiency’. AFRICA – New partnership for rice development in Africa formed. AFRICA – Ebola vaccine arrives in Liberia for large-scale trial. UNITED STATES – Researchers uncover key cancer-promoting gene. UNITED STATES – Brain scientists figure out how a protein crucial to learning and memory works. UNITED STATES – Scientists develop pioneering method to define stages of stem cell reprogramming. UNITED STATES – Researchers grow functional tissue-engineered intestine from human cells. UNITED STATES – A world first at the Montreal Heart Institute: Discovery of a personalized therapy for cardiovascular disease.

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Sixty Challenges – A 2030 Perspective on Natural Products and Medicines Security

Natural Product Communications ◽

10.1177/1934578x1701200849 ◽

2017 ◽

Vol 12 (8) ◽

pp. 1934578X1701200 ◽

Cited By ~ 1

Author(s):

Geoffrey A. Cordell

Keyword(s):

Climate Change ◽

Natural Products ◽

New Technologies ◽

Well Being ◽

Ageing Population ◽

Care Needs ◽

Future Health ◽

Traditional Medicines ◽

Market Expansion ◽

The Impact

Natural products matter, for they are essential contributors to societal well-being and global health. Flavors, fragrances, essential oils, traditional medicines and phytopharmaceuticals, and prescription and over-the-counter products all utilize constituent materials from natural sources. However, these vast natural resources of Earth are disappearing, and climate change and market expansion by a dramatically increasing and ageing population will continue to strain plant sourcing in the decades ahead. It was with these and other considerations that the term “ecopharmacognosy” was developed as both a philosophy and a practice, and from which the necessity for a “medicines security” strategy evolved. Extending previous presentations, a series of sixty challenges for 2030 to the status quo promotes the discussion of a different vision for the natural product sciences as applied to traditional medicines. Among the topics presented are areas for global collaborative initiatives in science and in data management, the impact of climate change on medicinal plant accessibility, the sustainability and quality of the natural products that patients receive, and the integration of new technologies, particularly the genomics of secondary metabolite biosynthesis, hand-held detection systems and artificial intelligence, and the implications of increased life expectancy on future health care needs. The presentation closes with two examples of newer approaches in drug discovery.

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Averting robo-bees: why free-flying robotic bees are a bad idea

Emerging Topics in Life Sciences ◽

10.1042/etls20190063 ◽

2019 ◽

Vol 3 (6) ◽

pp. 723-729

Author(s):

Roslyn Gleadow ◽

Jim Hanan ◽

Alan Dorin

Keyword(s):

Climate Change ◽

Computer Simulation ◽

Food Security ◽

European Countries ◽

Plant Interactions ◽

Plant Insect Interactions ◽

Native Habitat ◽

Insect Pollinators ◽

Insect Interactions

Food security and the sustainability of native ecosystems depends on plant-insect interactions in countless ways. Recently reported rapid and immense declines in insect numbers due to climate change, the use of pesticides and herbicides, the introduction of agricultural monocultures, and the destruction of insect native habitat, are all potential contributors to this grave situation. Some researchers are working towards a future where natural insect pollinators might be replaced with free-flying robotic bees, an ecologically problematic proposal. We argue instead that creating environments that are friendly to bees and exploring the use of other species for pollination and bio-control, particularly in non-European countries, are more ecologically sound approaches. The computer simulation of insect-plant interactions is a far more measured application of technology that may assist in managing, or averting, ‘Insect Armageddon' from both practical and ethical viewpoints.

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Modelling ecosystem adaptation and dangerous rates of global warming

Emerging Topics in Life Sciences ◽

10.1042/etls20180113 ◽

2019 ◽

Vol 3 (2) ◽

pp. 221-231 ◽

Cited By ~ 4

Author(s):

Rebecca Millington ◽

Peter M. Cox ◽

Jonathan R. Moore ◽

Gabriel Yvon-Durocher

Keyword(s):

Climate Change ◽

Global Warming ◽

Diffusion Rate ◽

Individual Species ◽

Genetic Evolution ◽

Rates Of Change ◽

Rapid Climate Change ◽

Warming Climate ◽

Intraspecies Competition ◽

High Trait

Abstract We are in a period of relatively rapid climate change. This poses challenges for individual species and threatens the ecosystem services that humanity relies upon. Temperature is a key stressor. In a warming climate, individual organisms may be able to shift their thermal optima through phenotypic plasticity. However, such plasticity is unlikely to be sufficient over the coming centuries. Resilience to warming will also depend on how fast the distribution of traits that define a species can adapt through other methods, in particular through redistribution of the abundance of variants within the population and through genetic evolution. In this paper, we use a simple theoretical ‘trait diffusion’ model to explore how the resilience of a given species to climate change depends on the initial trait diversity (biodiversity), the trait diffusion rate (mutation rate), and the lifetime of the organism. We estimate theoretical dangerous rates of continuous global warming that would exceed the ability of a species to adapt through trait diffusion, and therefore lead to a collapse in the overall productivity of the species. As the rate of adaptation through intraspecies competition and genetic evolution decreases with species lifetime, we find critical rates of change that also depend fundamentally on lifetime. Dangerous rates of warming vary from 1°C per lifetime (at low trait diffusion rate) to 8°C per lifetime (at high trait diffusion rate). We conclude that rapid climate change is liable to favour short-lived organisms (e.g. microbes) rather than longer-lived organisms (e.g. trees).

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