New Findings from Centrifuge Modeling of Rocking Shallow Foundations in Clayey Ground

Author(s):  
M. Hakhamaneshi ◽  
B. L. Kutter ◽  
L. Deng ◽  
T.C. Hutchinson ◽  
W. Liu
2014 ◽  
Vol 28 (2) ◽  
pp. 163-180
Author(s):  
Qiang Luo ◽  
Mao-tian Luan ◽  
Yun-ming Yang ◽  
Zhong-tao Wang ◽  
Shou-zheng Zhao

2016 ◽  
Vol 53 (3) ◽  
pp. 505-519 ◽  
Author(s):  
Mehdi Ashtiani ◽  
Abbas Ghalandarzadeh ◽  
Ikuo Towhata

Although the performance of surface, piled, and caisson foundations has been investigated against a large tectonic dislocation from a dip-slip fault, to date, the embedment depth has not been clearly considered on the behavior of shallow foundations subjected to dip-slip faulting. This paper presents a series of centrifuge model tests to investigate the effects of foundation embedment depth and contact pressure on the interaction of reverse faults and shallow foundations embedded at a depth of D. The effect of embedment depth on the behavior of a foundation was observed by comparing the results of the embedded foundation tests with those of surface foundation tests. The depth of the embedment, acting as a kinematic constraint, prevents the occurrence of sliding at the foundation–soil interface and consequently leads to significant foundation rotation and translation. Moreover, embedding the foundation causes the mechanism of the fault rupture – foundation interaction to change. The effect of contact pressure on the interaction of the fault rupture and the embedded foundations depends on the foundation position relative to the fault. In addition to the propagation of fault ruptures through the soil layer, passive failure wedges primarily occurred on both sides of the embedded foundations because of their translation and rotation, thereby imposing unfavorable effects on the adjacent structures.


2005 ◽  
Vol 25 (7-10) ◽  
pp. 773-783 ◽  
Author(s):  
Sivapalan Gajan ◽  
Bruce L. Kutter ◽  
Justin D. Phalen ◽  
Tara C. Hutchinson ◽  
Geoff R. Martin

Author(s):  
Andreia Sofia Pedroso da Silva Marques ◽  
Paulo Alexandre Lopes de Figueiredo Coelho ◽  
Stuart Haigh ◽  
Gopal Madabhushi

Author(s):  
Zhixian Wang ◽  
Pinjin Zhu ◽  
Jianhe Sun ◽  
Xuezheng Song

Hearing research is important not only for clinical, professional and military medicine, but also for toxicology, gerontology and genetics. Ultrastructure of the cochlea attracts much attention of electron microscopists, (1―3) but the research lags far behind that of the other parts of the organnism. On the basis of careful microdissection, technical improvment and accurate observation, we have got some new findings which have not been reported in the literature.We collected four cochleas from human corpses. Temporal bones dissected 1 h after death and cochleas perfused with fixatives 4 h after death were good enough in terms of preservation of fine structures. SEM:The apical surface of OHCs (Outer hair cells) and DTs (Deiters cells) is narrower than that of IPs (Inner pillar cells). The mosaic configuration of the reticular membrane is not typical. The stereocilia of IHCs (Inner hair cells) are not uniform and some kinocilia could be seen on the OHCs in adults. The epithelial surface of RM (Reissner’s membrane) is not smooth and no mesh could be seen on the mesothelial surface of RM. TEM.


2019 ◽  
Vol 476 (24) ◽  
pp. 3835-3847 ◽  
Author(s):  
Aliyath Susmitha ◽  
Kesavan Madhavan Nampoothiri ◽  
Harsha Bajaj

Most Gram-positive bacteria contain a membrane-bound transpeptidase known as sortase which covalently incorporates the surface proteins on to the cell wall. The sortase-displayed protein structures are involved in cell attachment, nutrient uptake and aerial hyphae formation. Among the six classes of sortase (A–F), sortase A of S. aureus is the well-characterized housekeeping enzyme considered as an ideal drug target and a valuable biochemical reagent for protein engineering. Similar to SrtA, class E sortase in GC rich bacteria plays a housekeeping role which is not studied extensively. However, C. glutamicum ATCC 13032, an industrially important organism known for amino acid production, carries a single putative sortase (NCgl2838) gene but neither in vitro peptide cleavage activity nor biochemical characterizations have been investigated. Here, we identified that the gene is having a sortase activity and analyzed its structural similarity with Cd-SrtF. The purified enzyme showed a greater affinity toward LAXTG substrate with a calculated KM of 12 ± 1 µM, one of the highest affinities reported for this class of enzyme. Moreover, site-directed mutation studies were carried to ascertain the structure functional relationship of Cg-SrtE and all these are new findings which will enable us to perceive exciting protein engineering applications with this class of enzyme from a non-pathogenic microbe.


1981 ◽  
Vol 26 (1) ◽  
pp. 44-45
Author(s):  
Michael Argyle

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