Blast Analysis of Aging Transportation Structures with Little Stand-Off Distance

Author(s):  
Yongwook Kim ◽  
Salvatore Florio ◽  
Qian Wang
Keyword(s):  
Genome ◽  
2018 ◽  
Vol 61 (9) ◽  
pp. 635-641
Author(s):  
Wei Luo ◽  
Nana Qin ◽  
Yang Mu ◽  
Huaping Tang ◽  
Mei Deng ◽  
...  

The translocation of 4AL/5AL in Triticum, which occurred before the differentiation of T. urartu and einkorn, is an important chromosomal rearrangement. Recently, the first identification of breakpoint sequence on 4AL for this translocation provides the opportunity to analyze the variation and diversity of breakpoints in Triticum. In this study, the breakpoint regions of 52 accessions from 21 species were isolated and further characterized. The sequences were divided into 12 types based on their lengths, which ranged from 2009 to 2552 bp. Cluster analysis showed that they were further divided into three groups. Interesting evolutionary relationships among a few of the species were observed and discussed. Multiple sequence alignment of the 52 sequences made it possible to detect 13 insertion and deletion length polymorphisms (InDels) and 101 single nucleotide polymorphisms (SNPs). Furthermore, several species- or accession-specific SNPs or InDels were also identified. Based on BLAST analysis of the conserved sequences, the breakpoint was narrowed down to a 125 bp fragment. Taken together, the results obtained in this study enrich our understanding of chromosomal breakpoints and will be useful for the identification of other breakpoints in wheat.


2016 ◽  
Vol 3 (2) ◽  
pp. 50 ◽  
Author(s):  
Atul Bajaj ◽  
Cijo John ◽  
Meenu Singh
Keyword(s):  

Author(s):  
M. R. Vineeth ◽  
I. D. Gupta ◽  
Archana Verma ◽  
Ankit Magotra ◽  
Rakesh Kumar ◽  
...  

Present study was done in thirty Karan Fries bulls to characterize the Exon 3 of PROP1 gene and to screen for the H173R polymorphism as well as other variations including reported and novel SNPs in the targeted region. The exon 3 was characterized by sequencing the amplicons obtained after PCR amplification using custom designed primers. The BLAST analysis of the obtained sequence yielded 100% and 99% homology with sequences of Bos taurus and bison respectively. The multiple alignment of the target region sequence with Bos taurus reference sequence revealed that the bulls under the study were free of H173R mutations. No variations were observed thus giving the targeted region a highly conserved one.


2020 ◽  
Vol 117 ◽  
pp. 104771
Author(s):  
R.R.C. Piyasena ◽  
D.P. Thambiratnam ◽  
T.H.T. Chan ◽  
N.J. Perera

Author(s):  
Phillip E. Prueter

Developing the realistic blast loading associated with an internal detonation occurring within a pressure vessel or heat exchanger is challenging. Unlike evaluation of external blast loading on structures due to far-field explosions, where typical overpressure-time histories can be reasonably defined based on empirical data, investigating confined detonations presents additional complications. The subsequent impulsive peak reflected overpressure from confined detonations acting on a structure can be extremely high due to the close proximity of the blast source to the vessel wall or pressure boundary. This establishes the possibility of significant structural damage for process equipment subjected to an internal detonation, even for relatively modest amounts of concentrated explosive products. This paper discusses the underlying theory of blast analysis and examines the practical application of non-linear, finite element based, explicit computational techniques for simulating the load acting on a structure due to internal and external blasts. The investigation of a recent, real-life industry failure of a heat exchanger due to a suspected internal detonation is discussed. Explicit, three-dimensional blast analysis is performed on the heat exchanger in question, and an internal detonation is simulated to reasonably replicate the considerable damage actually observed in the field. This analysis permits the determination of an approximate amount of concentrated product that caused the accidental explosion; that is, the plausible equivalent amount of explosives is back-calculated based on the predicted damage to the finite element model of the equipment in question. Computational iterations of varying charge amounts are performed and the predicted amount of permanent damage is documented so sensitivity to the hypothesized charge amount can be quantified. Furthermore, explicit blast analysis of nearby equipment is performed. In this investigation, computational results for both the heat exchanger (subjected to internal blast loading) and surrounding equipment (subjected to external blast loading) are in good agreement with the measured plastic deformations and failure modes that were actually observed in the field. Commentary on the likely detonation event that caused the significant damage observed is provided. Additionally, an advanced finite element failure criterion that is driven by plastic yielding is employed where portions of the computational model are removed from the simulation once a user-defined strain threshold is reached. This approach facilitates simulation of the gross heat exchanger pressure boundary failure actually observed in this case. The explicit finite element based analyses discussed in this study reasonably predict the structural response and damage characteristics corresponding to a recent, real-life industry failure.


Sign in / Sign up

Export Citation Format

Share Document