A non-free-space propagation x-ray phase contrast imaging method sensitive to phase effects in two directions simultaneously

2009 ◽  
Vol 94 (4) ◽  
pp. 044108 ◽  
Author(s):  
A. Olivo ◽  
S. E. Bohndiek ◽  
J. A. Griffiths ◽  
A. Konstantinidis ◽  
R. D. Speller
Keyword(s):  
Free Space ◽  
Phase Contrast ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
X Ray

scholarly journals Three-dimensional Construction of Micrometer Level in Rat Stomach by Synchrotron RadiationThree-dimensional Construction of Micrometer Level in Rat Stomach by Synchrotron Radiation

2020 ◽  
Author(s):  
Qiang Tao ◽  
Chen-Chen Gao ◽  
Xue-Hong Tong ◽  
Shizhen Yuan ◽  
Tian-tian Wang ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Phase Contrast ◽  
Three Dimensional ◽  
Image Resolution ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Rat Stomach ◽  
Contrast Imaging ◽  
X Ray ◽  
3 Dimensional

Abstract Objectives This article shows an imaging method of the stomach that does not use imaging agents. X-ray phase-contrast images of different stages of gastric development were taken using X-ray in-line phase-contrast imaging (XILPCI). The aim of the study was to demonstrate that XILPCI is a micron imaging method for gastric structures. Methods The stomachs of 4-, 6- and 12-week-old rats were removed and cleaned. XILPCI has 1000 times greater soft tissue contrast than that of X-ray traditional absorption radiography. The projection images of the rats’ stomachs were recorded by an XILPCI charge coupled device (CCD) at 9 μm image resolution. Results The X-ray in-line phase-contrast images of the different stages of rat gastric specimens clearly showed the gastric architectures and the details of the gastroduodenal region. 3-dimensional stomach anatomical structure images were reconstruction. Conclusion The reconstructed gastric 3D images can clearly display the internal structure of the stomach. XILPCI may be a useful method for medical research in the future. Keywords: Synchrotron radiation phase-contrast imaging, 3-dimensional gastric structure images

scholarly journals Tomographic reconstruction using tilted Laue analyser-based X-ray phase-contrast imaging

2021 ◽  
Vol 28 (1) ◽  
pp. 283-291
Author(s):  
M. C. Chalmers ◽  
M. J. Kitchen ◽  
K. Uesugi ◽  
G. Falzon ◽  
P. Quin ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Tomographic Reconstruction ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
Phase Gradient ◽  
X Ray ◽  
Sensitive Phase ◽  
Phase Contrast Method ◽  
Phase Sensitive

Analyser-based phase-contrast imaging (ABPCI) is a highly sensitive phase-contrast imaging method that produces high-contrast images of weakly absorbing materials. However, it is only sensitive to phase gradient components lying in the diffraction plane of the analyser crystal [i.e. in one dimension (1-D)]. In order to accurately account for and measure phase effects produced by the wavefield-sample interaction, ABPCI and other 1-D phase-sensitive methods must achieve 2-D phase gradient sensitivity. An inclined geometry method was applied to a Laue geometry setup for X-ray ABPCI through rotation of the detector and object about the optical axis. This allowed this traditionally 1-D phase-sensitive phase-contrast method to possess 2-D phase gradient sensitivity. Tomographic datasets were acquired over 360° of a multi-material phantom with the detector and sample tilted by 8°. The real and imaginary parts of the refractive index were reconstructed for the phantom.

scholarly journals Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources

2013 ◽  
Vol 8 (05) ◽  
pp. C05008-C05008 ◽  
Author(s):  
M Endrizzi ◽  
P C Diemoz ◽  
P R T Munro ◽  
C K Hagen ◽  
M B Szafraniec ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
X Ray

scholarly journals Edge-illumination X-ray phase contrast imaging: matching the imaging method to the detector technology

2014 ◽  
Vol 9 (11) ◽  
pp. C11004-C11004 ◽  
Author(s):  
M. Endrizzi ◽  
P.C. Diemoz ◽  
C.K. Hagen ◽  
F.A. Vittoria ◽  
P.R.T. Munro ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
X Ray ◽  
Detector Technology

scholarly journals Comprehensive assessment of myocardial remodeling in ischemic heart disease by synchrotron propagation based X-ray phase contrast imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ivo Planinc ◽  
Patricia Garcia-Canadilla ◽  
Hector Dejea ◽  
Ivana Ilic ◽  
Eduard Guasch ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Phase Contrast ◽  
Ex Vivo ◽  
Imaging Modality ◽  
Left Ventricular ◽  
Comprehensive Assessment ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
X Ray

AbstractCardiovascular research is in an ongoing quest for a superior imaging method to integrate gross-anatomical information with microanatomy, combined with quantifiable parameters of cardiac structure. In recent years, synchrotron radiation-based X-ray Phase Contrast Imaging (X-PCI) has been extensively used to characterize soft tissue in detail. The objective was to use X-PCI to comprehensively quantify ischemic remodeling of different myocardial structures, from cell to organ level, in a rat model of myocardial infarction. Myocardial infarction-induced remodeling was recreated in a well-established rodent model. Ex vivo rodent hearts were imaged by propagation based X-PCI using two configurations resulting in 5.8 µm and 0.65 µm effective pixel size images. The acquired datasets were used for a comprehensive assessment of macrostructural changes including the whole heart and vascular tree morphology, and quantification of left ventricular myocardial thickness, mass, volume, and organization. On the meso-scale, tissue characteristics were explored and compared with histopathological methods, while microstructural changes were quantified by segmentation of cardiomyocytes and calculation of cross-sectional areas. Propagation based X-PCI provides detailed visualization and quantification of morphological changes on whole organ, tissue, vascular as well as individual cellular level of the ex vivo heart, with a single, non-destructive 3D imaging modality.

scholarly journals Myocardial Remodeling in Ischemic Heart Disease – Imaging from Cell to Organ Level by Synchrotron Propagation Based X-Ray Phase-Contrast Imaging

2021 ◽  
Author(s):  
Ivo Planinc ◽  
Patricia Garcia-Canadilla ◽  
Hector Dejea ◽  
Ivana Ilic ◽  
Eduard Guasch ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Phase Contrast ◽  
Ex Vivo ◽  
Imaging Modality ◽  
Left Ventricular ◽  
Phase Contrast Imaging ◽  
Imaging Method ◽  
Contrast Imaging ◽  
X Ray ◽  
Organ Level

Abstract Background: Cardiovascular research is in an ongoing quest for a superior imaging method to integrate gross-anatomical information with microanatomy, combined with quantifiable parameters of cardiac structure. In recent years, synchrotron radiation-based X-ray Phase Contrast Imaging (X-PCI) has been extensively used to characterize soft tissue in detail.The objective was to use X-PCI to comprehensively quantify ischemic remodeling of different myocardial structures, from cell to organ level, in a rat model of myocardial infarction.Methods and Results: Myocardial infarction-induced remodeling was recreated in a well-established rodent model. Ex vivo rodent hearts were imaged by propagation based X-PCI using two configurations resulting in 5.8µm and 0.65µm effective pixel size images. The acquired datasets were used for a comprehensive assessment of macrostructural changes including the whole heart and vascular tree morphology, and quantification of left ventricular myocardial thickness, mass, volume, and organization. On the meso-scale, tissue characteristics were explored and compared with histopathological methods, while microstructural changes were quantified by segmentation of cardiomyocytes and calculation of cross-sectional areas.Conclusions: Propagation based X-PCI provides detailed visualization and quantification of morphological changes on whole organ, tissue, vascular as well as individual cellular level of the ex vivo heart, with a single, non-destructive 3D imaging modality.

Image Quality Analysis of X-ray Grating Interferometer Using Integrating-bucket Method

2020 ◽  
Vol 64 (2) ◽  
pp. 20503-1-20503-5
Author(s):  
Faiz Wali ◽  
Shenghao Wang ◽  
Ji Li ◽  
Jianheng Huang ◽  
Yaohu Lei ◽  
...  
Keyword(s):  
Image Quality ◽  
Phase Contrast ◽  
Quality Analysis ◽  
Phase Contrast Imaging ◽  
Phase Image ◽  
Contrast Imaging ◽  
High Quality ◽  
Image Quality Analysis ◽  
X Ray ◽  
Grating Interferometer

Abstract Grating-based x-ray phase-contrast imaging has the potential to enhance image quality and provide inner structure details non-destructively. In this work, using grating-based x-ray phase-contrast imaging system and employing integrating-bucket method, the quantitative expressions of signal-to-noise ratios due to photon statistics and mechanical error are analyzed in detail. Photon statistical noise and mechanical error are the main sources affecting the image noise in x-ray grating interferometry. Integrating-bucket method is a new phase extraction method translated to x-ray grating interferometry; hence, its image quality analysis would be of great importance to get high-quality phase image. The authors’ conclusions provide an alternate method to get high-quality refraction signal using grating interferometer, and hence increases applicability of grating interferometry in preclinical and clinical usage.

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