The type specimen of Murexia longicaudata (Dasyuromorphia : Dasyuridae): an enigma

2020 ◽  
Vol 42 (3) ◽  
pp. 359
Author(s):  
P. A. Woolley
Keyword(s):  
Type Specimen ◽  
Genetic Studies ◽  
Abnormal Individual

Examination of the skull and dentaries of the type specimen of Murexia longicaudata has led to the conclusion that the holotype is either a highly abnormal individual or that the skull and dentaries are mismatched. The dentaries may be those of a smaller individual. The matter might be resolved if genetic studies were to be carried out on both.

Scanning and Transmission Electron Microscopy of Human Red Blood Cells

1969 ◽  
Vol 27 ◽  
pp. 44-45
Author(s):  
A.J. Tousimis ◽  
T.R. Padden
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Blood Cells ◽  
Room Temperature ◽  
Type Specimen ◽  
New Combination ◽  
Human Red Blood Cells ◽  
Transmission Electron ◽  
Microscope Slides ◽  
Scanning Electron

The size, shape and surface morphology of human erythrocytes (RBC) were examined by scanning electron microscopy (SEM), of the fixed material directly and by transmission electron microscopy (TEM) of surface replicas to compare the relative merits of these two observational procedures for this type specimen.A sample of human blood was fixed in glutaraldehyde and washed in distilled water by centrifugation. The washed RBC's were spread on freshly cleaved mica and on aluminum coated microscope slides and then air dried at room temperature. The SEM specimens were rotary coated with 150Å of 60:40- gold:palladium alloy in a vacuum evaporator using a new combination spinning and tilting device. The TEM specimens were preshadowed with platinum and then rotary coated with carbon in the same device. After stripping the RBC-Pt-C composite film, the RBC's were dissolved in 2.5N HNO3 followed by 0.2N NaOH leaving the preshadowed surface replicas showing positive topography.

Moving beyond the “LDL hypothesis”

VASA ◽  
2015 ◽  
Vol 44 (5) ◽  
pp. 333-340 ◽  
Author(s):  
Christian Werner ◽  
Ulrich Laufs
Keyword(s):  
Ldl Cholesterol ◽  
Causal Relation ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Clinical Trial Data ◽  
Randomised Clinical Trial ◽  
Trial Data ◽  
Low Density Lipoprotein Cholesterol ◽  
Genetic Studies ◽  
Statin Drug

Abstract. Summary: The term “LDL hypothesis” is frequently used to describe the association of low-density lipoprotein cholesterol (LDL-cholesterol, LDL-C) and cardiovascular (CV) events. Recent data from genetic studies prove a causal relation between serum LDL-C and CV events. These data are in agreement with mechanistic molecular studies and epidemiology. New randomised clinical trial data show that LDL-C lowering with statins and a non-statin drug, ezetimibe, reduces CV events. We therefore believe that the “LDL-hypothesis” has been proven; the term appears to be outdated and should be replaced by “LDL causality”.

Neuropsychological intermediate phenotypes as tools for genetic studies in schizophrenia

2009 ◽  
Vol 42 (05) ◽  
Author(s):  
H Konnerth ◽  
I Giegling ◽  
AM Hartmann ◽  
J Genius ◽  
A Ruppert ◽  
...  
Keyword(s):  
Genetic Studies ◽  
Intermediate Phenotypes

The Use of Medical Record Linkage for Population and Genetic Studies

1969 ◽  
Vol 08 (01) ◽  
pp. 07-11 ◽  
Author(s):  
H. B. Newcombe
Keyword(s):  
Record Linkage ◽  
Large Scale ◽  
Medical Record Linkage ◽  
Canadian Province ◽  
Genetic Studies ◽  
Parental Characteristics ◽  
Family Histories ◽  
The Family ◽  
Large Populations ◽  
Machine Readable

Methods are described for deriving personal and family histories of birth, marriage, procreation, ill health and death, for large populations, from existing civil registrations of vital events and the routine records of ill health. Computers have been used to group together and »link« the separately derived records pertaining to successive events in the lives of the same individuals and families, rapidly and on a large scale. Most of the records employed are already available as machine readable punchcards and magnetic tapes, for statistical and administrative purposes, and only minor modifications have been made to the manner in which these are produced.As applied to the population of the Canadian province of British Columbia (currently about 2 million people) these methods have already yielded substantial information on the risks of disease: a) in the population, b) in relation to various parental characteristics, and c) as correlated with previous occurrences in the family histories.

Molecular genetic studies of canine inherited diseases

2011 ◽  
Author(s):  
Fabiana Helena Geraldo Farias
Keyword(s):  
Molecular Genetic ◽  
Genetic Studies ◽  
Inherited Diseases

Ellipsomyxa ariusi sp. nov. (Myxosporea: Ceratomyxidae), a new myxosporean infecting the gallbladder of threadfin sea catfish Arius arius in India

2020 ◽  
Vol 142 ◽  
pp. 83-97
Author(s):  
A Chandran ◽  
PU Zacharia ◽  
TV Sathianandan ◽  
NK Sanil
Keyword(s):  
Phylogenetic Analyses ◽  
Type Specimen ◽  
Ssu Rdna ◽  
Fish Host ◽  
Present Species ◽  
Epithelial Layer ◽  
Histopathological Changes ◽  
Mucus Production ◽  
High Bootstrap ◽  
A New Species

The present study describes a new species of myxosporean, Ellipsomyxa ariusi sp. nov., infecting the gallbladder of the threadfin sea catfish Arius arius (Hamilton, 1822). E. ariusi sp. nov. is characterized by bivalvular, ellipsoid or elongate-oval myxospores with smooth spore valves and a straight suture, arranged at an angle to the longitudinal spore axis. Mature myxospores measured 10.1 ± 0.8 µm in length, 6.8 ± 0.5 µm in width and 7.7 ± 0.7 µm in thickness. Polar capsules are equal in size and oval to pyriform in shape. They are positioned at an angle to the longitudinal myxospore axis and open in opposite directions. Polar capsules measured 2.8 ± 0.3 µm in length and 2.5 ± 0.4 µm in width; polar filaments formed 4-5 coils, and extended to 32.2 ± 2.1 µm in length. Monosporic and disporic plasmodial stages attached to the wall of gallbladder. Molecular analysis of the type specimen generated a 1703 bp partial SSU rDNA sequence (MN892546), which was identical to the isolates from 3 other locations. In phylogenetic analyses, genus Ellipsomyxa appeared monophyletic and E. ariusi sp. nov. occupied an independent position in maximum likelihood and Bayesian inference trees with high bootstrap values. The overall prevalence of infection was 54.8% and multiway ANOVA revealed that it varied significantly with location, year, season, sex and size of the fish host. Histopathological changes associated with E. ariusi sp. nov. infection included swelling, vacuolation and detachment of epithelial layer, reduced mucus production and altered consistency and colour of bile. Based on the morphologic, morphometric and molecular differences with known species of Ellipsomyxa, and considering differences in host and geographic locations, the present species is treated as new and the name Ellipsomyxa ariusi sp. nov. is proposed.

An annotated checklist of mesoplodont whale species (Cetacea, Ziphiidae) discovered during the nineteenth century

2015 ◽  
Vol 42 (2) ◽  
pp. 226-235 ◽  
Author(s):  
G. N. H. Waller
Keyword(s):  
Nineteenth Century ◽  
Additional Data ◽  
Original Description ◽  
Type Specimen ◽  
External Morphology ◽  
Type Locality ◽  
Type Material ◽  
Beaked Whale ◽  
Registration Number ◽  
Annotated Checklist

Eight species of mesoplodont whales (genus Mesoplodon Gervais, 1850) named during the nineteenth century are based on valid descriptions. A checklist with the original description and type material for each of these species is provided. Additional data given may include type locality and illustrative sources, type material holding institution and type registration number(s). The only type specimen for which a record of external morphology was published relates to the 1803 stranding of Sowerby's beaked whale (Mesoplodon bidens).

Archibald Menzies's visit to Isla del Coco, January 1795

2013 ◽  
Vol 40 (1) ◽  
pp. 149-156 ◽  
Author(s):  
E. Charles Nelson
Keyword(s):  
Type Specimen ◽  
Herbarium Specimens ◽  
Scientific Collections

Archibald Menzies landed twice at Chatham Bay, Isla del Coco, in January 1795. A small number of his herbarium specimens are extant, including the type specimen of Callicosta rugifolium (Bryophyta; Daltoniaceae) and perhaps also that of Octoea insularis (Angiospermae; Lauraceae), indicating that he was probably the first to make scientific collections on the island.

From the clinic to the research laboratory. The role of the clinician in molecular genetic studies

1993 ◽  
Vol 129 (11) ◽  
pp. 1424-1429
Author(s):  
S. E. Palmer
Keyword(s):  
Research Laboratory ◽  
Molecular Genetic ◽  
Genetic Studies
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