The influence of calcium, phosphorus and vitamin D supplementation of a pea–barley ration for growing pigs

1977 ◽  
Vol 28 (3) ◽  
pp. 543 ◽  
Author(s):  
BA Stone ◽  
GH McIntosh

A diet based on field peas and barley can satisfy the mineral requirements of growing pigs provided that calcium is supplemented at least to the level of dietary phosphorus present, and that vitamin D3 supplementation is greater than Agricultural Research Council recommendations. Bone fragility and lameness observed in pigs on a low calcium-low vitamin D3 diet was overcome by increasing either of these components, and this was accompanied by increased metacarpal ash and femur breaking strength. A similar response could also be produced by increasing dietary phosphorus levels. Plasma calcium and phosphate concentrations were significantly influenced by changes in the dietary calcium/phosphorus ratio, whereas vitamin D3 changes had a minimal influence. Parathyroid activity appeared to reflect the plasma calcium concentration. There did not appear to be any relationship between plasma concentrations and bone fragility or lameness.In order to ensure adequate bone development in pigs offered a diet of plant origin, vitamin D3 supplementation and elevation of dietary calcium to the level of total phosphorus present is a minimum requirement.

1971 ◽  
Vol 12 (2) ◽  
pp. 202-219 ◽  
Author(s):  
N.C. Nielsen ◽  
S. Andersen ◽  
A. Madsen ◽  
H.P. Mortensen

2020 ◽  
Vol 39 (7) ◽  
pp. 426-429
Author(s):  
Anna Agrusti ◽  
Sarah Contorno ◽  
Irene Bruno ◽  
Giulia Gortani ◽  
Egidio Barbi

Mouhamed, a 7-year-old boy of African origin, presented with progressive fatigue and difficulty in walking. He was never treated with vitamin D supplementation. The evaluation of his calcium-phosphorus metabolism revealed a myopathy related to severe rickets. Therefore, he was treated with high-dose vitamin D3 and myopathy and fatigue progressively resolved. Vitamin D plays a crucial role in the calcium-phosphorus metabolism, by acting on enterocytes, osteoclasts and renal tubule. Vitamin D deficiency is defined when the 25OHD value is less than 20 ng/ml. In order to guarantee the assumption of the minimum daily dose of vitamin D, it is recommended to start vitamin D3 supplementation in all newborns and infants in their first year of life, regardless of the feeding modality. Exposure to the sun is essential for the activation of vitamin D, so dark-skinned children and mothers or those little exposed to the sun should start vitamin D3 supplementation. Vitamin D3 should also be supplemented in children with cerebral palsy and in patients treated with anti-epileptic drugs. Other conditions at risk of vitamin D deficiency are inflammatory bowel disease, celiac disease, cystic fibrosis, obesity, liver failure, cholestasis and vegetarian or vegan diets. Classic signs of rickets are the rickety rosary, the widening of the wrist and the arching of the tibia. Severe hypocalcaemia secondary to vitamin D deficiency can occur with dilated cardiomyopathy or convulsions, especially in dark-skinned infants. Vitamin D deficiency should be considered in children with progressive myopathy or muscular weakness, especially in dark-skinned ones or in those poorly exposed to the sun for cultural or religious reasons.


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