scholarly journals Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

1977 ◽  
Vol 30 (4) ◽  
pp. 289 ◽  
Author(s):  
AA Gidley-Baird
Keyword(s):  
Corpus Luteum ◽  
Minimum Level ◽  
Plasma Progesterone ◽  
Mouse Plasma ◽  
Progesterone Production ◽  
Small Rise ◽  
Measurement Period

Measurement of plasma progesterone, LH and FSH were made every 6 h during the first 6 days of pregnancy in the mouse. Plasma progesterone and LH were low on day 1, minimum values being recorded at 24 h post coitus. Concentrations of both these hormones started rising during the second half of day 2 with the rise continuing during day 3 to a progesterone peak of 25 ng/ml early on day 4 and an LH peak of 37 ng/mllate on day 4. Levels of progesterone fell during day 4 and LH during day 5 to approximately half their respective peak values and then remained relatively constant over the remainder of the measurement period. Levels of FSH, which were high early on day 1 (180 ng/ml), fell sharply by midday with a small rise late in the day followed by a decline during day 2 to a minimum level of 20 ng/ml at 48 h post coitus. Early on day 3 FSH values rose to 120 ng/ml then fell to 50-60 ng/ml during the next 6 h and remained relatively stable at this level during days 4 and 5. It is suggested that LH is concerned with progesterone production and maintenance of the corpus luteum whilst FSH is concerned with the production of oestrogen required for implantation in this species.

CORPUS LUTEUM ACTIVITY AND PROSTAGLANDIN LEVELS AFTER PARTURITION IN COWS WITH RETAINED FETAL MEMBRANES

1987 ◽  
Vol 67 (1) ◽  
pp. 21-26 ◽  
Author(s):  
PIERRE MATTON ◽  
VICTOR ADELAKOUN ◽  
JACQUES DUFOUR
Keyword(s):  
Key Words ◽  
Corpus Luteum ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Fetal Membranes ◽  
Plasma Progesterone ◽  
Blood Samples ◽  
Retained Placenta ◽  
Progesterone Production ◽  
Prostaglandin F

Previous results have shown that progesterone levels were higher on the day of parturition in cows with retained fetal membranes (RFM) than in cows with normal calving, suggesting incomplete lysis of the corpus luteum (CL). This experiment was performed to evaluate the activity of the CL and the level of 13,14-dihydro-15-keto prostaglandin F2α (PGFM) in RFM cows. Cows with RFM or those calving normally (NC) were ovariectomized 12–14 h after parturition. Blood samples were taken from the caudal and utero-ovarian veins. Slices of CL were incubated with or without human chorionic gonadotrophin (hCG) medium for 3 h. Plasma progesterone was higher in both the caudal and utero-ovarian veins of RFM cows than in those of NC cows (1.12 ± 0.25 vs. 0.62 ± 0.08 ng mL−1 and 2.4 ± 0.3 vs. 1.44 ± 0.33 ng mL−1, respectively). PGFM was also significantly higher in RFM cows (3.62 ± 0.19 vs. 2.55 ± 0.15 ng mL−1). Progesterone production by CL slices from both types of cows, incubated without hCG, was similar (65 ± 4.2 vs. 73 ± 5.1 μg g−1); with hCG, however, the progesterone production by the CL of RFM cows was 186.3 ± 10.7 μg g−1, 75.7 μg g−1 more than in CL of cows with normal calving. These results support the hypothesis of an incomplete luteolysis of the CL in RFM cows in spite of hieher levels of PGF2α. Key words: Corpus luteum activity, progesterone, prostaglandin, postpartum cows, retained placenta

THE SITE OF PROGESTERONE PRODUCTION IN EARLY PREGNANCY

1971 ◽  
Vol 67 (2) ◽  
pp. 353-361 ◽  
Author(s):  
Tore H:son Holmdahl ◽  
Elof D. B. Johansson ◽  
Leif Wide
Keyword(s):  
Protein Binding ◽  
Corpus Luteum ◽  
Early Pregnancy ◽  
Plasma Levels ◽  
Disappearance Rate ◽  
Plasma Progesterone ◽  
Progesterone Production ◽  
Vacuum Aspiration ◽  
Competitive Protein Binding

ABSTRACT The disappearance of progesterone* and HCG from the plasma was measured following therapeutic abortions in 17 patients from the seventh to the sixteenth week of pregnancy. Between the seventh and the twelfth week of gestation the evacuation of the uterine contents was performed by vacuum aspiration, and from the thirteenth week onwards abdominal hysterotomy was performed. Plasma progesterone was assayed using a competitive protein binding technique, while plasma HCG was determined by a radioimmunosorbent assay. After the evacuation of the uterine contents in the early pregnancy cases (weeks 7–8) the plasma levels of progesterone remained elevated much longer than in the later stages of pregnancy (weeks 12–16), thus suggesting that the corpus luteum graviditatis was the main source of progesterone in the first group, while in the last group the placenta was the main source of progesterone production. When comparing the earlier and later cases of pregnancy, the disappearance rate of plasma HCG remained essentially unaltered. From the results obtained, it seems likely that the transition from the ovarian to the placental production of progesterone occurs during the ninth to eleventh weeks of pregnancy.

Follicle vascularity coordinates corpus luteum blood flow and progesterone production

2017 ◽  
Vol 29 (3) ◽  
pp. 448 ◽  
Author(s):  
S. G. S. de Tarso ◽  
G. D. A. Gastal ◽  
S. T. Bashir ◽  
M. O. Gastal ◽  
G. A. Apgar ◽  
...  
Keyword(s):  
Blood Flow ◽  
Corpus Luteum ◽  
Doppler Ultrasonography ◽  
Beef Cows ◽  
Regression Analyses ◽  
Preovulatory Follicle ◽  
Colour Doppler ◽  
Plasma Progesterone ◽  
Colour Doppler Ultrasonography ◽  
Progesterone Production

Colour Doppler ultrasonography was used to compare the ability of preovulatory follicle (POF) blood flow and its dimensions to predict the size, blood flow and progesterone production capability of the subsequent corpus luteum (CL). Cows (n = 30) were submitted to a synchronisation protocol. Follicles ≥7 mm were measured and follicular wall blood flow evaluated every 12 h for approximately 3.5 days until ovulation. After ovulation, cows were scanned daily for 8 days and similar parameters were evaluated for the CL. Blood samples were collected and plasma progesterone concentrations quantified. All parameters were positively correlated. Correlation values ranged from 0.26 to 0.74 on data normalised to ovulation and from 0.31 to 0.74 on data normalised to maximum values. Correlations between calculated ratios of both POF and CL in data normalised to ovulation and to maximum values ranged from moderate (0.57) to strong (0.87). Significant (P < 0.0001) linear regression analyses were seen in all comparisons. In conclusion, higher correlations were observed between the dimensions of POF and/or CL and blood flow of both structures, as well as POF and/or CL blood flow with plasma progesterone concentrations of the resultant CL. These findings indicate that follicle vascularity coordinates CL blood flow and progesterone production in synchronised beef cows.

PROGESTERONE IN THE HUMAN PERIPHERAL BLOOD IN THE PREOVULATORY PERIOD OF THE MENSTRUAL CYCLE

1967 ◽  
Vol 55 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Benno Runnebaum ◽  
Josef Zander
Keyword(s):  
Menstrual Cycle ◽  
Corpus Luteum ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Progesterone Concentration ◽  
Plasma Progesterone ◽  
Progesterone Secretion ◽  
Graafian Follicle ◽  
The Mean ◽  
Mean Concentration

ABSTRACT Progesterone was determined and identified in human peripheral blood during the preovulatory period of the menstrual cycle, by combined isotope derivative and recrystallization analysis. The mean concentration of progesterone in 1.095 ml of plasma obtained 9 days before ovulation was 0.084 μg/100 ml. However, the mean concentration of progesterone in 1.122 ml of plasma obtained 4 days before ovulation was 0.279 μg/100 ml. These data demonstrate a source of progesterone secretion other than the corpus luteum. The higher plasma-progesterone concentration 4 days before ovulation may indicate progesterone secretion of the ripening Graafian follicle of the ovary.

The role of insulin-like growth factor-I (IGF-I) and estradiol in rabbit corpus luteum progesterone production

Endocrine ◽  
1997 ◽  
Vol 6 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Serena H. Chen ◽  
Vanna Zanagnolo ◽  
Sangchai Preutthipan ◽  
Kenneth P. Roberts ◽  
Sandra B. Goodman ◽  
...  
Keyword(s):  
Growth Factor ◽  
Corpus Luteum ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Progesterone Production ◽  
Igf I ◽  
Growth Factor I

GONADAL HORMONES AND THE CONTROL OF OVULATION IN THE GUINEA-PIG

1972 ◽  
Vol 55 (3) ◽  
pp. 599-607 ◽  
Author(s):  
B. T. DONOVAN ◽  
A. N. LOCKHART
Keyword(s):  
Guinea Pig ◽  
Corpus Luteum ◽  
Acute Treatment ◽  
Gonadal Hormones ◽  
Time Of Day ◽  
Gonadal Steroids ◽  
Corpora Lutea ◽  
Plasma Progesterone ◽  
Gonadotrophin Secretion ◽  
Oestradiol Benzoate

SUMMARY The release of ovulating hormone after acute treatment with gonadal steroids, or corpus luteum removal on different days of the oestrous cycle, was studied in the guinea-pig. Injection of 25, 50 or 100 μg oestradiol or 2·5 mg progesterone on day 13 of the cycle had no effect upon gonadotrophin secretion as judged by follicular histology, but markedly altered the sizes of the corpora lutea of the previous ovulation. Treatment with oestradiol on day 14 did not elicit gonadotrophin secretion. However, administration of the same hormones to animals given 10 μg oestradiol benzoate 24 h earlier caused ovulation or follicular luteinization. Progesterone (2·5 mg) appeared least effective in stimulating gonadotrophin release; 25 μg oestradiol were more effective when given at 12.00 h than at 24.00 h but treatment with both hormones caused ovulation when given at either time of day. Luteal volumes were not affected. Removal of corpora lutea during the second half of the cycle advanced the time of expected ovulation to day 15 or earlier when the procedure was carried out on days 8 or 9, but not on days 10–13. It is concluded that 4–5 days must elapse between the fall in plasma progesterone level associated with corpus luteum regression and the release of ovulating hormone.

Oxytocin may play a role in the control of the human corpus luteum

1982 ◽  
Vol 95 (1) ◽  
pp. 65-70 ◽  
Author(s):  
G. J. S. Tan ◽  
R. Tweedale ◽  
J. S. G. Biggs
Keyword(s):  
Menstrual Cycle ◽  
Corpus Luteum ◽  
Inhibitory Action ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Corpora Lutea ◽  
Luteal Cells ◽  
Progesterone Production ◽  
Human Corpus Luteum

The effects of oxytocin on dispersed luteal cells from human corpora lutea of the menstrual cycle were studied. Oxytocin at a concentration of 4 mi.u./ml produced a slight increase in basal progesterone production. However, higher oxytocin concentrations (400 and 800 mi.u./ml) markedly inhibited both basal and human chorionic gonadotrophin-induced progesterone production. These data provide evidence for an effect of oxytocin on the human corpus luteum. In view of the inhibitory action of oxytocin, increased secretion of this hormone may be important in the demise of the corpus luteum at the end of the menstrual cycle.

Development and regression of the corpus luteum in grey seal (Halichoerus grypus) ovaries and its use in determining fertility rates

1984 ◽  
Vol 62 (6) ◽  
pp. 1095-1100 ◽  
Author(s):  
I. L. Boyd
Keyword(s):  
Corpus Luteum ◽  
Adult Female ◽  
Halichoerus Grypus ◽  
Embryonic Diapause ◽  
Grey Seal ◽  
Fertility Rates ◽  
Reproductive Condition ◽  
Plasma Progesterone ◽  
Blood Samples ◽  
Foetal Growth

Adult female grey seals were sampled at the Fame Islands at monthly intervals from November 1980 to October 1981. The distribution, size, and number of ovarian corpora were recorded in each case and blood samples were obtained for progesterone analysis. The concentration of plasma progesterone was about 6 ng/mL for most of gestation, including embryonic diapause, and rose to about 10 ng/mL during the final month. Progesterone declined sharply to less than 1 ng/mL at parturition. The size of the corpus luteum was constant throughout embryonic diapause, but after implantation it grew continuously until parturition. Following parturition, it regressed rapidly at first, forming a corpus albicans, and then more slowly, regression being arrested during the period of foetal growth of the following reproductive cycle. Most corpora albicantia had disappeared 1 year after their formation. Corpora albicantia may be useful indicators of reproductive history in grey seals, providing that allowance is made for the reproductive condition of females at the time of sampling and for several other possible errors which could arise. Retrospective calculation of reproductive statistics by more than 1 year using corpora albicantia is not valid for grey seals.

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