Prevalence and risk factors of erectile dysfunction in patients with hepatitis B virus or hepatitis C virus or chronic liver disease: results from a prospective study

Background Approximately 300 million people are affected by hepatitis B virus (HBV) or hepatitis C virus (HCV) infection worldwide. Erectile dysfunction (ED) is a frequent condition that impairs the quality of life and can be associated with several chronic disorders (type 2 diabetes mellitus, atherosclerosis, depression). Few studies have evaluated the prevalence of ED in patients with HBV and HCV chronic infection. The aim of this study was to evaluate the prevalence and the risk factors of ED in a cohort of patients with HBV or HCV-related chronic liver diseases. Methods: Consecutive patients with HCV and HBV chronic infection were enrolled. Results: In total, 89 out (49 with cirrhosis, 21 with HBV and 68 with HCV infection) were included in this study. ED was diagnosed in 76.4% of patients. The use of phosphodiesterase type 5 inhibitors was reported by 21.3% of patients. Patients with ED were older and had a higher rate of cirrhosis and diabetes mellitus compared with patients without ED. At multivariate analysis, diabetes mellitus and stage of liver disease (cirrhosis vs chronic hepatitis) were the only independent predictors of ED. Conclusion: Due to the high rate of ED in outpatients with viral-related liver disease and the underuse of phosphodiesterase type 5 inhibitors, a larger study focussed on these patients is needed.

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Prevalence, severity, and risk factors of liver disease in blood donors positive in a second-generation anti?hepatitis c virus screening test1, 2

Hepatology ◽

10.1016/0270-9139(95)90524-3 ◽

1995 ◽

Vol 21 (3) ◽

pp. 725-729 ◽

Cited By ~ 1

Author(s):

L SERFATY

Keyword(s):

Risk Factors ◽

Hepatitis C Virus ◽

Liver Disease ◽

Hepatitis C ◽

Screening Test ◽

Blood Donors ◽

Second Generation ◽

Virus Screening

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Testing for Hepatitis C Virus Infection Among Adults Aged ≥18 in the United States, 2013-2017

Public Health Reports ◽

10.1177/00333549211047236 ◽

2021 ◽

pp. 003335492110472

Author(s):

Hope King ◽

J. E. Soh ◽

William W. Thompson ◽

Jessica Rogers Brown ◽

Karina Rapposelli ◽

...

Keyword(s):

United States ◽

Risk Factors ◽

Hepatitis C Virus ◽

Liver Disease ◽

Hepatitis C ◽

The United States ◽

Hcv Infection ◽

High School Education ◽

Related Risk ◽

Hcv Testing

Objective Approximately 2.4 million people in the United States are living with hepatitis C virus (HCV) infection. The objective of our study was to describe demographic and socioeconomic characteristics, liver disease–related risk factors, and modifiable health behaviors associated with self-reported testing for HCV infection among adults. Methods Using data on adult respondents aged ≥18 from the 2013-2017 National Health Interview Survey, we summarized descriptive data on sociodemographic characteristics and liver disease–related risk factors and stratified data by educational attainment. We used weighted logistic regression to examine predictors of HCV testing. Results During the study period, 11.7% (95% CI, 11.5%-12.0%) of adults reported ever being tested for HCV infection. Testing was higher in 2017 than in 2013 (adjusted odds ratio [aOR] = 1.27; 95% CI, 1.18-1.36). Adults with ≥some college were significantly more likely to report being tested (aOR = 1.60; 95% CI, 1.52-1.69) than adults with ≤high school education. Among adults with ≤high school education (but not adults with ≥some college), those who did not have health insurance were less likely than those with private health insurance (aOR = 0.78; 95% CI, 0.68-0.89) to get tested, and non–US-born adults were less likely than US-born adults to get tested (aOR = 0.77; 95% CI, 0.68-0.87). Conclusions Rates of self-reported HCV testing increased from 2013 to 2017, but testing rates remained low. Demographic characteristics, health behaviors, and liver disease–related risk factors may affect HCV testing rates among adults. HCV testing must increase to achieve hepatitis C elimination targets.

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Proportion of Nonalcoholic Steatohepatitis in Patients with Chronic Liver Disease

10.53350/pjmhs211561272 ◽

2021 ◽

Vol 15 (6) ◽

pp. 1272-1274

Author(s):

H.A. Abro ◽

B. A. Shaikh ◽

A. H. Mugheri ◽

I. A. Ansari ◽

Z. A. Shaikh ◽

...

Keyword(s):

Liver Cirrhosis ◽

Hepatitis C Virus ◽

Liver Disease ◽

Hepatitis C ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Nonalcoholic Steatohepatitis ◽

Smoking Status ◽

Virus Hepatitis ◽

B Virus

Aim: To determine the frequency of nonalcoholic steatohepatitis in patients with liver cirrhosis. Study Design: Retrospective/observational Place and Duration of Study: Department of Medicine, Chandka Medical College Hospital, Larkana from 1st July 2020 to 31st March 2021. Methodology: One hundred and twenty patients of both genders presented with liver cirrhosis were enrolled in this study. Patient’s detailed demographics including age, sex, body mass index, smoking status, alcohol consumption and family history of liver disease were recorded after taking written informed consent. Laboratory examination was done to examine the proportion of hepatitis B virus, hepatitis C virus and nonalcoholic steatohepatitis. Results: There were 68 (56.67%) males and 52 (43.33%) were females with mean age 45.74±10.54 years. Among all the patients hepatitis C virus was found in 62 (51.67%) patients, 15 (12.5%) had hepatitis B virus, 17 (14.17%) had hepatitis B virus + hepatitis C virus and nonalcoholic steatohepatitis was found in 26 (21.67%) patients. Conclusion: Nonalcoholic steatohepatitis was the major cause of liver cirrhosis in Pakistani population. The proportion of NASH in liver cirrhosis patients was 21.67%. Keywords: Nonalcoholic steatohepatitis (NASH), Liver Cirrhosis, Hepatitis B virus, Hepatitis C virus

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Epidemiology of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Related Hepatocellular Carcinoma

The Open Virology Journal ◽

10.2174/1874357901812010026 ◽

2018 ◽

Vol 12 (1) ◽

pp. 26-32 ◽

Cited By ~ 66

Author(s):

Arnolfo Petruzziello

Keyword(s):

Risk Factors ◽

Hepatocellular Carcinoma ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Hbv Infection ◽

Sub Saharan Africa ◽

Liver Cancers ◽

B Virus

Introduction:Hepatocellular carcinoma (HCC) is one of the most prevalent primary malignant tumors and accounts for about 90% of all primary liver cancers. Its distribution varies greatly according to geographic location and it is more common in middle and low- income countries than in developed ones especially in Eastern Asia and Sub Saharan Africa (70% of all new HCCs worldwide), with incidence rates of over 20 per 100,000 individuals.Explanation:The most important risk factors for HCC are Hepatitis B Virus (HBV) infection, Hepatitis C Virus (HCV) infection, excessive consumption of alcohol and exposition to aflatoxin B1. Its geographic variability and heterogeneity have been widely associated with the different distribution of HBV and HCV infections worldwide.Chronic HBV infection is one of the leading risk factors for HCC globally accounting for at least 50% cases of primary liver tumors worldwide. Generally, while HBV is the main causative agent in the high incidence HCC areas, HCV is the major etiological factor in low incidence HCC areas, like Western Europe and North America.Conclusion:HBV-induced HCC is a complex, stepwise process that includes integration of HBV DNA into host DNA at multiple or single sites. On the contrary, the cancerogenesis mechanism of HCV is not completely known and it still remains controversial as to whether HCV itself plays a direct role in the development of tumorigenic progression.

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Seroprevalence and risk factors of Hepatitis B virus and Hepatitis C virus infections among children attending govern- ment medical college, Gwalior M.P.

Indian Journal of Medical Microbiology ◽

10.1016/j.ijmmb.2021.08.310 ◽

2021 ◽

Vol 39 ◽

pp. S89-S90

Author(s):

Anshu Mittal ◽

Savita Bharat Jain

Keyword(s):

Risk Factors ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Virus Infections ◽

Medical College ◽

B Virus

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Peculiarities of correction of sexual function in men presenting with diabetes mellitus

Diabetes Mellitus ◽

10.14341/2072-0351-5484 ◽

2010 ◽

Vol 13 (3) ◽

pp. 30-31

Author(s):

Roman Viktorovich Rozhivanov ◽

Alexander Evgen'evich Lepetukhin ◽

Sergey Anatol'evich Dubskiy ◽

Dmitriy Gennad'evich Kurbatov

Keyword(s):

Diabetes Mellitus ◽

Erectile Dysfunction ◽

Sexual Function ◽

Lipoic Acid ◽

Research Centre ◽

Alpha Lipoic Acid ◽

Phosphodiesterase Type 5 Inhibitors ◽

Phosphodiesterase Type

Diabetes mellitus (DM) is frequently associated with disturbances of the sexual function underlain by hypogonadism and neuropathy. These pathologicalconditions are successfully managed by androgens, alpha-lipoic acid, and phosphodiesterase type 5 inhibitors, besides compensation of carbohydratemetabolism. This paper reports results of evaluation of different methods for the treatment of erectile dysfunction in DM patients basedat Endocrinological Research Centre. Their combination ensured higher than 90% efficiency of therapy.

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