Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1709064114 ◽

2017 ◽

Vol 114 (30) ◽

pp. 7744-7746 ◽

Author(s):

Martin Jastroch

Keyword(s):

Reactive Oxygen Species ◽

Adipose Tissue ◽

Brown Adipose Tissue ◽

Uncoupling Protein ◽

Reactive Oxygen ◽

Oxygen Species ◽

Uncoupling Protein 1 ◽

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Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2011.12.009 ◽

2012 ◽

Vol 1817 (3) ◽

pp. 410-418 ◽

Author(s):

Peter Schönfeld ◽

Lech Wojtczak

Keyword(s):

Reactive Oxygen Species ◽

Fatty Acids ◽

Adipose Tissue ◽

Brown Adipose Tissue ◽

Uncoupling Protein ◽

Reactive Oxygen ◽

Oxygen Species ◽

Uncoupling Protein 1 ◽

Brown Adipose ◽

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The role of UCP 1 in production of reactive oxygen species by mitochondria isolated from brown adipose tissue

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2010.04.008 ◽

2010 ◽

Vol 1797 (8) ◽

pp. 1470-1476 ◽

Author(s):

Andrea Dlasková ◽

Kieran J. Clarke ◽

Richard K. Porter

Keyword(s):

Reactive Oxygen Species ◽

Adipose Tissue ◽

Brown Adipose Tissue ◽

Reactive Oxygen ◽

Oxygen Species ◽

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The Use of Reactive Oxygen Species Production by Succinate-Driven Reverse Electron Flow as an Index of Complex 1 Activity in Isolated Brown Adipose Tissue Mitochondria

Methods in Molecular Biology - Mitochondrial Regulation ◽

10.1007/978-1-0716-1433-4_13 ◽

2021 ◽

pp. 247-258

Author(s):

Andrea Dlasková ◽

Kieran J. Clarke ◽

Mary F. Rooney ◽

Richard K. Porter

Keyword(s):

Reactive Oxygen Species ◽

Adipose Tissue ◽

Brown Adipose Tissue ◽

Reactive Oxygen Species Production ◽

Electron Flow ◽

Reactive Oxygen ◽

Oxygen Species ◽

Brown Adipose ◽

Reverse Electron Flow ◽

Species Production

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UCP1 ablation increases the production of reactive oxygen species by mitochondria isolated from brown adipose tissue

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2010.04.256 ◽

2010 ◽

Vol 1797 ◽

pp. 85

Author(s):

Andrea Dlasková ◽

Kieran J. Clarke ◽

Richard K. Porter

Keyword(s):

Reactive Oxygen Species ◽

Adipose Tissue ◽

Brown Adipose Tissue ◽

Reactive Oxygen ◽

Oxygen Species ◽

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Limited proteolysis reveals conformational changes in uncoupling protein-1 from brown adipose tissue mitochondria

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2003.07.005 ◽

2003 ◽

Vol 420 (1) ◽

pp. 40-45 ◽

Author(s):

Shu-Gui Huang

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Conformational Changes ◽

Uncoupling Protein ◽

Limited Proteolysis ◽

Uncoupling Protein 1 ◽

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Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis

Diabetes ◽

10.2337/diabetes.53.3.577 ◽

2004 ◽

Vol 53 (3) ◽

pp. 577-584 ◽

Author(s):

M. A. Christoffolete ◽

C. C.G. Linardi ◽

L. de Jesus ◽

K. N. Ebina ◽

S. D. Carvalho ◽

...

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Uncoupling Protein ◽

Uncoupling Protein 1 ◽

Targeted Disruption ◽

Adaptive Thermogenesis ◽

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Undecanesulfonate does not allosterically activate H+ uniport mediated by uncoupling protein-1 in brown adipose tissue mitochondria

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2006.05.011 ◽

2006 ◽

Vol 38 (11) ◽

pp. 1965-1974 ◽

Author(s):

Petr Ježek ◽

Tomáš Špaček ◽

Keith Garlid ◽

Martin Jabůrek

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Uncoupling Protein ◽

Uncoupling Protein 1 ◽

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Uncoupling protein-1 deficiency promotes brown adipose tissue inflammation and ER stress

PLoS ONE ◽

10.1371/journal.pone.0205726 ◽

2018 ◽

Vol 13 (11) ◽

pp. e0205726 ◽

Author(s):

Laura M. Bond ◽

Maggie S. Burhans ◽

James M. Ntambi

Keyword(s):

Adipose Tissue ◽

Er Stress ◽

Brown Adipose Tissue ◽

Uncoupling Protein ◽

Adipose Tissue Inflammation ◽

Uncoupling Protein 1 ◽

Tissue Inflammation ◽

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Physiological Significance of Mitochondrial Uncoupling Protein 1 in the Prevention of Reactive Oxygen Species and Control of Substrate Oxidation

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.lb585 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Martin Jastroch ◽

Susanne Keipert ◽

Carola W Meyer ◽

Maria Kutschke ◽

Gerhard Heldmaier ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Uncoupling Protein ◽

Reactive Oxygen ◽

Substrate Oxidation ◽

Physiological Significance ◽

Oxygen Species ◽

Uncoupling Protein 1 ◽

Mitochondrial Uncoupling ◽

Mitochondrial Uncoupling Protein ◽

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The Importance of Calcium Ions for Determining Mitochondrial Glycerol-3-Phosphate Dehydrogenase Activity When Measuring Uncoupling Protein 1 (UCP1) Function in Mitochondria Isolated from Brown Adipose Tissue

Mitochondrial Bioenergetics - Methods in Molecular Biology ◽

10.1007/978-1-4939-7831-1_19 ◽

2018 ◽

pp. 325-336 ◽

Author(s):

Kieran J. Clarke ◽

Richard K. Porter

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Dehydrogenase Activity ◽

Calcium Ions ◽

Uncoupling Protein ◽

Uncoupling Protein 1 ◽

Brown Adipose ◽

Glycerol 3 Phosphate Dehydrogenase

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