scholarly journals Coinfection with multiple strains of the Epstein-Barr virus in human immunodeficiency virus-associated hairy leukoplakia.

1992 ◽  
Vol 89 (14) ◽  
pp. 6560-6564 ◽  
Author(s):  
D. M. Walling ◽  
S. N. Edmiston ◽  
J. W. Sixbey ◽  
M. Abdel-Hamid ◽  
L. Resnick ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Hairy Leukoplakia ◽  
Immunodeficiency Virus ◽  
Epstein Barr ◽  
Multiple Strains

Epstein-Barr Virus Coinfection and Recombination in Non-Human Immunodeficiency Virus-Associated Oral Hairy Leukoplakia

1995 ◽  
Vol 171 (5) ◽  
pp. 1122-1130 ◽  
Author(s):  
D. M. Walling ◽  
N. M. Clark ◽  
D. M. Markovitz ◽  
T. S. Frank ◽  
D. K. Braun ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Oral Hairy Leukoplakia ◽  
Hairy Leukoplakia ◽  
Immunodeficiency Virus ◽  
Epstein Barr

scholarly journals Epstein-Barr virus-related oral T-cell lymphoma associated with human immunodeficiency virus immunosuppression

Blood ◽  
1993 ◽  
Vol 81 (12) ◽  
pp. 3350-3356 ◽  
Author(s):  
JA Thomas ◽  
F Cotter ◽  
AM Hanby ◽  
LQ Long ◽  
PR Morgan ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Barr Virus ◽  
Ebv Infection ◽  
Hairy Leukoplakia ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Epstein-Barr virus (EBV) is generally held to infect B cells and epithelial cells, although there are now reports of EBV infection in normal T cells and neoplastic T-cell diseases. In patients with human immunodeficiency virus (HIV) infection, EBV is associated with the benign epithelial lesion, hairy leukoplakia, and has been reported in up to 80% of acquired immunodeficiency syndrome (AIDS)-related B-cell lymphoma. This study shows the presence of EBV in malignant oral T-cell lymphoma in three AIDS patients, two of whom had concurrent manifestation of hairy leukoplakia. The T-cell lineage of the tumor cells was determined by positive immunophenotyping for T-cell markers and lack of B-cell or nonhematopoietic (cytokeratin) determinants. All tumors contained monoclonal T-cell populations shown by polymerase chain reaction, which showed amplification of T-cell receptor gamma chain DNA without evidence of Ig heavy chain gene rearrangement. Furthermore, these lesions showed the presence of EBV DNA and expression of EBV latent gene products in the tumor cells. EBV involvement in AIDS-related T-cell lymphoma has not been widely reported and may represent a further manifestation of opportunistic EBV infection arising in the HIV-immunocompromised host.

scholarly journals Epstein-Barr virus-related oral T-cell lymphoma associated with human immunodeficiency virus immunosuppression

Blood ◽  
1993 ◽  
Vol 81 (12) ◽  
pp. 3350-3356 ◽  
Author(s):  
JA Thomas ◽  
F Cotter ◽  
AM Hanby ◽  
LQ Long ◽  
PR Morgan ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Barr Virus ◽  
Ebv Infection ◽  
Hairy Leukoplakia ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Abstract Epstein-Barr virus (EBV) is generally held to infect B cells and epithelial cells, although there are now reports of EBV infection in normal T cells and neoplastic T-cell diseases. In patients with human immunodeficiency virus (HIV) infection, EBV is associated with the benign epithelial lesion, hairy leukoplakia, and has been reported in up to 80% of acquired immunodeficiency syndrome (AIDS)-related B-cell lymphoma. This study shows the presence of EBV in malignant oral T-cell lymphoma in three AIDS patients, two of whom had concurrent manifestation of hairy leukoplakia. The T-cell lineage of the tumor cells was determined by positive immunophenotyping for T-cell markers and lack of B-cell or nonhematopoietic (cytokeratin) determinants. All tumors contained monoclonal T-cell populations shown by polymerase chain reaction, which showed amplification of T-cell receptor gamma chain DNA without evidence of Ig heavy chain gene rearrangement. Furthermore, these lesions showed the presence of EBV DNA and expression of EBV latent gene products in the tumor cells. EBV involvement in AIDS-related T-cell lymphoma has not been widely reported and may represent a further manifestation of opportunistic EBV infection arising in the HIV-immunocompromised host.

Epstein - Barr virus epidemiology in HIV infected transsexuals

2021 ◽  
pp. 1-11
Author(s):  
Sadia Salahuddin ◽  
Joharia Azhar ◽  
Hasham Akhtar ◽  
Jabbar Khan ◽  
Noor Muhammad
Keyword(s):  
Human Immunodeficiency Virus ◽  
Epstein Barr Virus ◽  
Qualitative Assessment ◽  
Genotype 1 ◽  
Virus Genotype ◽  
Blood Samples ◽  
Barr Virus ◽  
Genotype 2 ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Abstract Objectives: To molecularly characterise the relationship between Epstein-Barr virus genotypes and Pashtun ethnicity. Method: The cross-sectional study was conducted from November 2018 to December 2019 after approval from the Gomal University, Dera Ismail Khan, Pakistan, and comprised blood samples from transgender sex workers who were seropositive for human immunodeficiency virus-1 and seronegative for human immunodeficiency virus residing in two cities of Khyber Pakhtunkhwa province and Islamabad, the federal capital. Formalin-fixed paraffin-embedded samples were collected retrospectively, but collection of blood samples from the study subjects was purely on the basis of physical availability. ?-globin gene and EBER-1 were amplified for qualitative assessment and existence of Epstein-Barr virus. Characterisation of EBNA-2 was done through nested polymerase chain reaction. Results: Of the 80 subjects, 40(50%) each were seropositive and seronegative individuals. The overall mean age was 28±6.917 years. Among the seropositive group, 38(95%) were homosexual and 2(5%) were heterosexual. Among the seropositive group, 16(40%) had Epstein-Barr virus genotype 1 and 6(15%) had genotype 2, while co-infections were found in 2(5%) subjects. In the seronegative group, 36(90%) subjects had Epstein-Barr virus genotype 1, while there was no case of genotype 2 or co-infection. EBV-2 genotypes with HIV seropositivity showed strong association (p=0.005). Amplification for the EBER-1 gene was done in all the 80(100%) samples. Conclusion: Epstein-Barr virus EBV genotype 1 was found to be the most frequent type, while genotype 2 and co-infections were detected only seropositive samples. Continuous...

scholarly journals Pancytopenia Secondary to SARS-CoV 2 Infection-A Case Reprt

2021 ◽  
Author(s):  
Neeraj Sharma ◽  
Rajat Shukla ◽  
Rachna Warrier ◽  
Kunal Kumar ◽  
Nalin Singh ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Blood Cells ◽  
Epstein Barr Virus ◽  
Viral Infections ◽  
Parvovirus B19 ◽  
Rare Complication ◽  
Elderly Male ◽  
Barr Virus ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Abstract Pancytopenia is a condition when person has low count of all three types of blood cells causing a triage of anemia, leukopenia and thrombocytopenia. It should not be considered as a disease in itself but rather the sign of a disease that needs to be further evaluated. Among the various causes, viral infections like Human Immunodeficiency Virus, Cytomegalovirus, Epstein-Barr virus and Parvovirus B19 have been implicated. Pancytopenia is a rare complication and not commonly seen in patients with COVID 19 disease. Here, we report a case of pancytopenia in previously immunocompetent elderly male patient with SARS-CoV2 infection.

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