Activation of the Receptor for Advanced Glycation End Products Triggers a p21ras-dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress

Journal of Biological Chemistry ◽

10.1074/jbc.272.28.17810 ◽

1997 ◽

Vol 272 (28) ◽

pp. 17810-17814 ◽

Author(s):

Harry M. Lander ◽

James M. Tauras ◽

Jason S. Ogiste ◽

Osamu Hori ◽

Rebecca A. Moss ◽

...

Keyword(s):

Protein Kinase ◽

Advanced Glycation End Products ◽

Oxidant Stress ◽

Mitogen Activated Protein Kinase ◽

Advanced Glycation ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein ◽

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High Levels of Dietary Advanced Glycation End Products Transform Low-Dersity Lipoprotein Into a Potent Redox-Sensitive Mitogen-Activated Protein Kinase Stimulant in Diabetic Patients

Circulation ◽

10.1161/01.cir.0000135587.92455.0d ◽

2004 ◽

Vol 110 (3) ◽

pp. 285-291 ◽

Author(s):

Weijing Cai ◽

John Cijiang He ◽

Li Zhu ◽

Melpomeni Peppa ◽

Changyong Lu ◽

...

Keyword(s):

Protein Kinase ◽

Advanced Glycation End Products ◽

Mitogen Activated Protein Kinase ◽

Diabetic Patients ◽

Advanced Glycation ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein

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Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways

Basic Research in Cardiology ◽

10.1007/s00395-008-0738-8 ◽

2008 ◽

Vol 104 (1) ◽

pp. 42-49 ◽

Author(s):

Chengbo Sun ◽

Chun Liang ◽

Yusheng Ren ◽

Yi Zhen ◽

Zhiqing He ◽

...

Keyword(s):

Protein Kinase ◽

Progenitor Cells ◽

Endothelial Progenitor Cells ◽

Advanced Glycation End Products ◽

Mitogen Activated Protein Kinase ◽

Advanced Glycation ◽

Endothelial Progenitor ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein

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High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis

Diabetes Obesity and Metabolism ◽

10.1111/j.1463-1326.2004.00387.x ◽

2005 ◽

Vol 7 (4) ◽

pp. 448-454 ◽

Author(s):

S.-Y. Li ◽

Y. Liu ◽

V. K. Sigmon ◽

A. McCort ◽

J. Ren

Keyword(s):

Protein Kinase ◽

High Fat Diet ◽

Mitogen Activated Protein Kinase ◽

High Fat ◽

Advanced Glycation ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein

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Advanced Glycation End Products Affect Osteoblast Proliferation and Function by Modulating Autophagy Via the Receptor of Advanced Glycation End Products/Raf Protein/Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase/Extracellular Signal-regulated Kinase (RAGE/Raf/MEK/ERK) Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m115.669499 ◽

2015 ◽

Vol 290 (47) ◽

pp. 28189-28199 ◽

Author(s):

Hong-Zheng Meng ◽

Wei-Lin Zhang ◽

Fei Liu ◽

Mao-Wei Yang

Keyword(s):

Advanced Glycation End Products ◽

Mitogen Activated Protein Kinase ◽

Erk Pathway ◽

Advanced Glycation ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein ◽

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Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)36966-1 ◽

1994 ◽

Vol 269 (13) ◽

pp. 9889-9897 ◽

Author(s):

S.D. Yan ◽

A.M. Schmidt ◽

G.M. Anderson ◽

J. Zhang ◽

J. Brett ◽

...

Keyword(s):

Advanced Glycation End Products ◽

Binding Proteins ◽

Oxidant Stress ◽

Advanced Glycation ◽

Glycation End Products ◽

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Advanced glycation end products inhibit intracellular calcium concentration in colon smooth muscle cells in a protein kinase C-dependent manner

World Chinese Journal of Digestology ◽

10.11569/wcjd.v22.i6.874 ◽

2014 ◽

Vol 22 (6) ◽

pp. 874

Author(s):

Ying Zhu

Keyword(s):

Smooth Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Advanced Glycation End Products ◽

Calcium Concentration ◽

Dependent Manner ◽

Advanced Glycation ◽

Kinase C ◽

Glycation End Products ◽

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Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor- B in human osteoarthritis chondrocytes

Rheumatology ◽

10.1093/rheumatology/keq380 ◽

2010 ◽

Vol 50 (5) ◽

pp. 838-851 ◽

Author(s):

Z. Rasheed ◽

N. Akhtar ◽

T. M. Haqqi

Keyword(s):

Advanced Glycation End Products ◽

Nuclear Factor ◽

Advanced Glycation ◽

Factor B ◽

Mitogen Activated Protein Kinases ◽

Advanced Glycation End Product ◽

Glycation End Products ◽

End Products ◽

Mitogen Activated Protein ◽

Osteoarthritis Chondrocytes

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Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.91.16.7742 ◽

1994 ◽

Vol 91 (16) ◽

pp. 7742-7746 ◽

Author(s):

J. L. Wautier ◽

M. P. Wautier ◽

A. M. Schmidt ◽

G. M. Anderson ◽

O. Hori ◽

...

Keyword(s):

Advanced Glycation End Products ◽

Diabetic Complications ◽

Vessel Wall ◽

Oxidant Stress ◽

Advanced Glycation ◽

Specific Receptor ◽

Glycation End Products ◽

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Activation of the Receptor for Advanced Glycation END Products (RAGE) and Oxidative Stress Mediate Up-Regulation of RHOA/Rho Kinase Pathway and Smooth Muscle Contraction in Diabetes

Gastroenterology ◽

10.1016/s0016-5085(11)61527-8 ◽

2011 ◽

Vol 140 (5) ◽

pp. S-374 ◽

Author(s):

Sunila Mahavadi ◽

Olivia Manion ◽

Shobha Ghosh ◽

Karnam S. Murthy

Keyword(s):

Oxidative Stress ◽

Smooth Muscle ◽

Advanced Glycation End Products ◽

Smooth Muscle Contraction ◽

Advanced Glycation ◽

Glycation End Products ◽

End Products ◽

Kinase Pathway ◽

And Oxidative Stress

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Advanced Glycation End Products (AGE) Potently Induce Autophagy through Activation of RAF Protein Kinase and Nuclear Factor κB (NF-κB)

Journal of Biological Chemistry ◽

10.1074/jbc.m115.667576 ◽

2015 ◽

Vol 291 (3) ◽

pp. 1481-1491 ◽

Author(s):

Neeharika Verma ◽

Sunil K. Manna

Keyword(s):

Protein Kinase ◽

Advanced Glycation End Products ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Advanced Glycation ◽

Glycation End Products ◽

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