Down-regulation of the ATP-binding Cassette Transporter 2 (Abca2) Reduces Amyloid-β Production by Altering Nicastrin Maturation and Intracellular Localization

Vasiliki Michaki; Francesc X. Guix; Krist'l Vennekens; Sebastian Munck; Colin Dingwall; John B. Davis; Danyelle M. Townsend; Kenneth D. Tew; Fabian Feiguin; Bart De Strooper; Carlos G. Dotti; Tina Wahle

doi:10.1074/jbc.m111.288258

Down-regulation of the ATP-binding Cassette Transporter 2 (Abca2) Reduces Amyloid-β Production by Altering Nicastrin Maturation and Intracellular Localization

Journal of Biological Chemistry ◽

10.1074/jbc.m111.288258 ◽

2011 ◽

Vol 287 (2) ◽

pp. 1100-1111 ◽

Cited By ~ 24

Author(s):

Vasiliki Michaki ◽

Francesc X. Guix ◽

Krist'l Vennekens ◽

Sebastian Munck ◽

Colin Dingwall ◽

...

Keyword(s):

Intracellular Localization ◽

Amyloid Β ◽

Atp Binding ◽

Down Regulation ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier

Neurochemistry International ◽

10.1016/j.neuint.2007.12.002 ◽

2008 ◽

Vol 52 (6) ◽

pp. 956-961 ◽

Cited By ~ 29

Author(s):

Shin-ichi Akanuma ◽

Sumio Ohtsuki ◽

Youko Doi ◽

Masanori Tachikawa ◽

Shingo Ito ◽

...

Keyword(s):

Blood Brain Barrier ◽

Amyloid Β ◽

Brain Barrier ◽

Atp Binding ◽

Amyloid Β Peptide ◽

Efflux Transport ◽

Atp Binding Cassette Transporter ◽

Blood Brain ◽

The Brain ◽

Atp Binding Cassette

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22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid β Secretion

Journal of Biological Chemistry ◽

10.1074/jbc.m300044200 ◽

2003 ◽

Vol 278 (15) ◽

pp. 13244-13256 ◽

Cited By ~ 152

Author(s):

Radosveta P. Koldamova ◽

Iliya M. Lefterov ◽

Milos D. Ikonomovic ◽

John Skoko ◽

Preslav I. Lefterov ◽

...

Keyword(s):

Retinoic Acid ◽

Cholesterol Efflux ◽

Amyloid Β ◽

Brain Cells ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Impact of 27-Hydroxycholesterol on Amyloid-β Peptide Production and ATP-Binding Cassette Transporter Expression in Primary Human Neurons

Journal of Alzheimer s Disease ◽

10.3233/jad-2009-0944 ◽

2009 ◽

Vol 16 (1) ◽

pp. 121-131 ◽

Cited By ~ 30

Author(s):

Woojin Scott Kim ◽

Sharon L. Chan ◽

Andrew F. Hill ◽

Gilles J. Guillemin ◽

Brett Garner

Keyword(s):

Amyloid Β ◽

Atp Binding ◽

Amyloid Β Peptide ◽

Atp Binding Cassette Transporter ◽

Human Neurons ◽

Transporter Expression ◽

Atp Binding Cassette

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Down-regulation of ATP-binding cassette transporter G1 expression by unmethylated CpG oligodeoxynucleotides in RAW 264.7 macrophages

Experimental & Molecular Medicine ◽

10.3858/emm.2011.43.9.058 ◽

2011 ◽

Vol 43 (9) ◽

pp. 510

Author(s):

Jeong Min Seo ◽

Ji-Young Lee ◽

Geun Eog Ji ◽

Ji Chang You

Keyword(s):

Atp Binding ◽

Raw 264.7 ◽

Down Regulation ◽

Raw 264.7 Macrophages ◽

Cpg Oligodeoxynucleotides ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Down‐regulation of ATP‐binding cassette transporter A1 (ABCA1) and ABCG1 expression by unsaturated fatty acids in vivo and in vitro

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.691.15 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Young‐Ki Park ◽

Heather E Rasmussen ◽

Sarah J Ehlers ◽

Chai Siah Ku ◽

Elliot D Jesch ◽

...

Keyword(s):

Fatty Acids ◽

Unsaturated Fatty Acids ◽

Atp Binding ◽

Down Regulation ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Faculty Opinions recommendation of Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1090378.543628 ◽

2007 ◽

Author(s):

Rahul Kuver

Keyword(s):

Common Variant ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Faculty Opinions recommendation of Coordination of polymerization, chain termination, and export in assembly of the Escherichia coli lipopolysaccharide O9a antigen in an ATP-binding cassette transporter-dependent pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165867.628944 ◽

2009 ◽

Author(s):

Miguel Valvano

Keyword(s):

Escherichia Coli ◽

Chain Termination ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Dependent Pathway ◽

Escherichia Coli Lipopolysaccharide ◽

Polymerization Chain ◽

Atp Binding Cassette

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Insights into chlorantraniliprole resistance of Chilo suppressalis: Expression profiles of ATP-binding cassette transporter genes in strains ranging from low- to high-level resistance

Journal of Asia-Pacific Entomology ◽

10.1016/j.aspen.2021.02.006 ◽

2021 ◽

Author(s):

Yingchuan Peng ◽

Jun Zhao ◽

Yang Sun ◽

Peng Wan ◽

Yanyue Hu ◽

...

Keyword(s):

Expression Profiles ◽

Atp Binding ◽

Chilo Suppressalis ◽

Atp Binding Cassette Transporter ◽

High Level ◽

Level Resistance ◽

Atp Binding Cassette

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Nucleotide-induced conformational changes of MalK, a bacterial ATP binding cassette transporter protein.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)32014-8 ◽

1994 ◽

Vol 269 (32) ◽

pp. 20456-20461

Author(s):

E. Schneider ◽

S. Wilken ◽

R. Schmid

Keyword(s):

Conformational Changes ◽

Atp Binding ◽

Transporter Protein ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Cadmium tolerance mediated by the yeast AP-1 protein requires the presence of an ATP-binding cassette transporter-encoding gene, YCF1.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)31675-2 ◽

1994 ◽

Vol 269 (51) ◽

pp. 32592-32597 ◽

Cited By ~ 1

Author(s):

J A Wemmie ◽

M S Szczypka ◽

D J Thiele ◽

W S Moye-Rowley

Keyword(s):

Atp Binding ◽

Cadmium Tolerance ◽

Atp Binding Cassette Transporter ◽

Encoding Gene ◽

Atp Binding Cassette

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