The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)

Alexander S. Shavkunov; Norelle C. Wildburger; Miroslav N. Nenov; Thomas F. James; Tetyana P. Buzhdygan; Neli I. Panova-Elektronova; Thomas A. Green; Ronald L. Veselenak; Nigel Bourne; Fernanda Laezza

doi:10.1074/jbc.m112.445924

The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)

Journal of Biological Chemistry ◽

10.1074/jbc.m112.445924 ◽

2013 ◽

Vol 288 (27) ◽

pp. 19370-19385 ◽

Cited By ~ 57

Author(s):

Alexander S. Shavkunov ◽

Norelle C. Wildburger ◽

Miroslav N. Nenov ◽

Thomas F. James ◽

Tetyana P. Buzhdygan ◽

...

Keyword(s):

Growth Factor ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Fibroblast Growth ◽

Voltage Gated Sodium Channel ◽

Voltage Gated

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Structure of the Ternary Complex of the C-Terminus of the Voltage-Gated Sodium Channel (NaV) with Calmodulin (CaM) and Fibroblast Growth Factor Homologous Factor (FHF)

Biophysical Journal ◽

10.1016/j.bpj.2012.11.782 ◽

2013 ◽

Vol 104 (2) ◽

pp. 137a

Author(s):

Ben C. Chung ◽

Chao-Jian Wang ◽

Haidun Yan ◽

Geoffrey Pitt ◽

Seok-Yong Lee

Keyword(s):

Growth Factor ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Ternary Complex ◽

Fibroblast Growth ◽

Voltage Gated Sodium Channel ◽

Voltage Gated ◽

C Terminus

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Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6

Journal of Biological Chemistry ◽

10.1074/jbc.m115.703868 ◽

2016 ◽

Vol 291 (21) ◽

pp. 11268-11284 ◽

Cited By ~ 15

Author(s):

Syed R. Ali ◽

Aditya K. Singh ◽

Fernanda Laezza

Keyword(s):

Amino Acid ◽

Growth Factor ◽

Structure Function ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Amino Acid Residues ◽

Voltage Gated Sodium Channel ◽

Voltage Gated

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Elucidating the Structural Constituents of Fibroblast Growth Factor 14 that Confer its Modulatory Effects on the Voltage-Gated Sodium Channel 1.6

Biophysical Journal ◽

10.1016/j.bpj.2020.11.1126 ◽

2021 ◽

Vol 120 (3) ◽

pp. 156a

Author(s):

Nolan M. Dvorak ◽

Paul Wadsworth ◽

Pingyuan Wang ◽

Haiying Chen ◽

Jia Zhou ◽

...

Keyword(s):

Growth Factor ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Fibroblast Growth ◽

Voltage Gated Sodium Channel ◽

Voltage Gated

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Glycogen synthase kinase 3 controls endochondral bone development: Contribution of fibroblast growth factor 18

Developmental Biology ◽

10.1016/j.ydbio.2005.07.029 ◽

2005 ◽

Vol 285 (2) ◽

pp. 496-507 ◽

Cited By ~ 20

Author(s):

Ravi M. Kapadia ◽

Anyonya R. Guntur ◽

Martina I. Reinhold ◽

Michael C. Naski

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Glycogen Synthase ◽

Bone Development ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Fibroblast Growth ◽

Endochondral Bone

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Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.12.031 ◽

2019 ◽

Vol 29 (3) ◽

pp. 413-419 ◽

Cited By ~ 5

Author(s):

Zhiqing Liu ◽

Paul Wadsworth ◽

Aditya K. Singh ◽

Haiying Chen ◽

Pingyuan Wang ◽

...

Keyword(s):

Growth Factor ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Protein Interactions ◽

Fibroblast Growth ◽

Chemical Probes ◽

Protein Protein Interactions ◽

Voltage Gated Sodium Channel ◽

Voltage Gated

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Quantitative Proteomics Reveals Protein–Protein Interactions with Fibroblast Growth Factor 12 as a Component of the Voltage-Gated Sodium Channel 1.2 (Nav1.2) Macromolecular Complex in Mammalian Brain

Molecular & Cellular Proteomics ◽

10.1074/mcp.m114.040055 ◽

2015 ◽

Vol 14 (5) ◽

pp. 1288-1300 ◽

Cited By ~ 27

Author(s):

Norelle C. Wildburger ◽

Syed R. Ali ◽

Wei-Chun J. Hsu ◽

Alexander S. Shavkunov ◽

Miroslav N. Nenov ◽

...

Keyword(s):

Growth Factor ◽

Sodium Channel ◽

Fibroblast Growth Factor ◽

Protein Interactions ◽

Quantitative Proteomics ◽

Mammalian Brain ◽

Macromolecular Complex ◽

Fibroblast Growth ◽

Protein Protein Interactions ◽

Voltage Gated

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Fibroblast Growth Factor 1 Regulates Signaling via the Glycogen Synthase Kinase-3β Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m202803200 ◽

2002 ◽

Vol 277 (36) ◽

pp. 32985-32991 ◽

Cited By ~ 80

Author(s):

Makoto Hashimoto ◽

Yutaka Sagara ◽

Dianne Langford ◽

Ian P. Everall ◽

Margaret Mallory ◽

...

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Glycogen Synthase ◽

Glycogen Synthase Kinase ◽

Fibroblast Growth ◽

Glycogen Synthase Kinase 3Β

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Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel

Molecular Cancer ◽

10.1186/1476-4598-6-76 ◽

2007 ◽

Vol 6 (1) ◽

pp. 76 ◽

Cited By ~ 33

Author(s):

Pinar Uysal-Onganer ◽

Mustafa BA Djamgoz

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Sodium Channel ◽

Human Prostate ◽

Human Prostate Cancer ◽

Voltage Gated Sodium Channel ◽

Voltage Gated ◽

Epidermal Growth

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Inhibiting glycogen synthase kinase-3 and transforming growth factor-β signaling to promote epithelial transition of human adipose mesenchymal stem cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2017.07.036 ◽

2017 ◽

Vol 490 (4) ◽

pp. 1381-1388 ◽

Cited By ~ 9

Author(s):

Melina Setiawan ◽

Xiao-Wei Tan ◽

Tze-Wei Goh ◽

Gary Hin-Fai Yam ◽

Jodhbir S. Mehta

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Growth Factor ◽

Transforming Growth Factor ◽

Glycogen Synthase ◽

Transforming Growth Factor Β ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Adipose Mesenchymal Stem Cells

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A Negative Feedback Control of Transforming Growth Factor-β Signaling by Glycogen Synthase Kinase 3-mediated Smad3 Linker Phosphorylation at Ser-204

Journal of Biological Chemistry ◽

10.1074/jbc.m109.016667 ◽

2009 ◽

Vol 284 (30) ◽

pp. 19808-19816 ◽

Cited By ~ 55

Author(s):

Caroline Millet ◽

Motozo Yamashita ◽

Mary Heller ◽

Li-Rong Yu ◽

Timothy D. Veenstra ◽

...

Keyword(s):

Growth Factor ◽

Feedback Control ◽

Negative Feedback ◽

Transforming Growth Factor ◽

Glycogen Synthase ◽

Transforming Growth Factor Β ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Negative Feedback Control

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