scholarly journals Transglutaminase II/MicroRNA-218/-181a Loop Regulates Positive Feedback Relationship between Allergic Inflammation and Tumor Metastasis

2014 ◽  
Vol 289 (43) ◽  
pp. 29483-29505 ◽  
Author(s):  
Sangkyung Eom ◽  
Youngmi Kim ◽  
Misun Kim ◽  
Deokbum Park ◽  
Hansoo Lee ◽  
...  
2014 ◽  
Vol 289 (17) ◽  
pp. 12126-12144 ◽  
Author(s):  
Sangkyung Eom ◽  
Youngmi Kim ◽  
Deokbum Park ◽  
Hansoo Lee ◽  
Yun Sil Lee ◽  
...  

2020 ◽  
Author(s):  
Jiang Xu ◽  
Zhongzu Zhang ◽  
Lu Huang ◽  
Rongping Zhou ◽  
LinXuan Feng ◽  
...  

Abstract BackgroundCancer stem cells (CSCs) have been documented to be closely related with tumor metastasis and recurrence, and the same important role were identified in Ewing Sarcoma (ES). In our previous study, we found that let-7a was repressed in ES. Herein, we further identified its putative effects in the CSCs of ES. ResultsThe expression of let-7a was consistently suppressed in the separated ES SP cells, which were identified to contain the characteristics of the stem cells. The ability of colony formation or invasion of ES SP cells was suppressed in vitro when we restored the expression of let-7a. The same results were found in the tumor growth of ES SP cells’ xenograft mice in vivo. Furthermore, we found STAT3 and lin28 were involved in the suppressive effects.ConclusionLet-7a, STAT3 and lin28 might form a positive circuit to regulate the malignant phenotype of ES CSCs.


2019 ◽  
Vol 128 (3) ◽  
pp. 228-233 ◽  
Author(s):  
Brianne L. Glazier ◽  
Lynn E. Alden

2006 ◽  
Author(s):  
Holley S. Hodgins ◽  
Kathryn Adair ◽  
Rachel Gordon ◽  
Yaritza Saavedra ◽  
Sara Shiffman ◽  
...  

2011 ◽  
Author(s):  
Kent Harber ◽  
Jamie L. Gorman ◽  
Frank P. Gengaro ◽  
Samantha Butisingh ◽  
Rebecca Ouellette ◽  
...  

2018 ◽  
Vol 13 (Number 1) ◽  
pp. 55-67
Author(s):  
Shafini M. Shafie ◽  
Zakirah Othman ◽  
N Hami

Malaysia has an abundance of biomass resources that can be utilised for power generation. One of them is paddy residue. Paddy residue creates ahuge potential in the power generation sector. The consumption of paddy residue can help Malaysia become less dependent on conventional sources of energy, mitigate greenhouse gas(GHG) emission, offer positive feedback in the economic sector, and at the same time, provide thebest solution for waste management activities. The forecast datafor 20 years on electricity generation wasused to calculate the GHG emission and its saving when paddy residue is used for electricity generation. The government’scost saving was also identified when paddy residue substituted coal fuel in electricity generation.This paper can provide forecast information so that Malaysia is able to move forward to apply paddy residue as feedstock in energy supply. Hopefully, the data achieved can encourage stakeholder bodies in the implementation of paddy residue inelectricity generation since there is apositive impact towardscost and emission saving.


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