Ischaemic versus non-ischaemic: how does heart failure aetiology affect pulmonary arterial capacitance and pulmonary artery pulsatility index in end-stage heart failure?

2021 ◽  
pp. 1-7
Author(s):  
Zubeyde Bayram ◽  
Cem Dogan ◽  
Suleyman C. Efe ◽  
Busra Guvendi ◽  
Ali Karagoz ◽  
...  
2018 ◽  
Vol 28 (2) ◽  
pp. 86-90
Author(s):  
Povilas Jakuška ◽  
Rasa Veisaitė ◽  
Rokas Ereminas ◽  
Vilija Grumuldytė ◽  
Ramūnas Bolys ◽  
...  

Background. In the end stage heart failure (HF) patients with moderate to severe tricuspid regurgitation (TR), the surgical decision for tricuspid valve (TV) repair during left ventricular assist device (LVAD) implantation surgery is not clear. Methods. We included 31 patient with end-stage heart failure and moderate to severe TVR (≥II degree) to our retrospective study analysis. 19 patients received TV annuloplasty during LVAD implantation (TVR+ group), whereas 12 patients didn’t (TVR- group). Demographic, clinical and echocardiographic parameters were assessed in both groups preoperatively and 1 month after surgery. Overall 12 months survival was analysed with Kaplan – Meier method and compared between groups. Results. Inhospital or 30 days mortality rate in TVR+ and TVR- groups was 21.1% and 8.3%, respectively (p=0.624). The overall survival rates up to 12 months did not differ between groups (75% vs 57.89%, p=0.452). TV regurgitation grade was reduced significantly after LVAD implantation with (p=0.001) and without TV repair (p=0.008). Dimensions of RV and right atrium decreased in TVR+ group (p<0.001). The size of RV did not change significantly in TVRgroup postoperatively, however, the diameter of right atrium reduced significantly in this group (p=0.01). Systolic and mean pulmonary artery pressures decreased significantly in both groups of patients. The indices of RV longitudinal function were reduced preoperatively and did not change after LVAD implantation with and without TV repair. Conclusions. Pulmonary artery pressures decreased in all patients after LVAD implantation, while the diameter of RV reduced significantly in patients after concomitant TV repair. Early postoperative mortality and 1 year survival rates did not differ between end stage heart failure patients after LVAD implantation with or without TV annuloplasty.


2003 ◽  
Vol 9 (5) ◽  
pp. S108
Author(s):  
Michael W Schaeffer ◽  
Ginger A Conway ◽  
Barbara J Bell ◽  
Rosann M Giesting ◽  
Lynne E Wagoner

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


2006 ◽  
Vol 5 (1) ◽  
pp. 126-126
Author(s):  
S DRAKOS ◽  
E KALDARA ◽  
M BONIOS ◽  
D KARAGEORGOPOULOS ◽  
C PIERRAKOS ◽  
...  

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