This chapter looks at the tensions between biblical interpretation and the political, social, and cultural context of dissenting Protestant churches in the twentieth century. It notes that even a fundamental category, such as the ‘inspiration’ of Scripture, shifted across time as the nature of public debates, social and economic structures, and Western definitions of public knowledge shifted. The chapter progresses by looking at a number of examples of key figures (R. J. Campbell, Harry Emerson Fosdick, H. G. Guinness, R. A. Torrey, and R. G. McIntyre among them) who interpreted the Bible for public comment, and their relative positions as the century progressed. Popularization of biblical interpretation along the lines of old, new, and contemporary dissent, is explored through the careers of three near contemporaries: Charles Bradley ‘Chuck’ Templeton (b. 1915, Toronto, Canada), William Franklin ‘Billy’ Graham, Jr (b. 1918, North Carolina), and Oral Roberts (b. 1918, Oklahoma).