Long-Term Effects of Social Isolation in Nonsocially Adapted Rhesus Monkeys

1968 ◽  
Vol 113 (1) ◽  
pp. 117-128 ◽  
Author(s):  
G. D. Mitchell ◽  
D. L. Clark
1966 ◽  
Vol 18 (2) ◽  
pp. 567-580 ◽  
Author(s):  
G. D. Mitchell ◽  
E. J. Raymond ◽  
G. C. Ruppenthal ◽  
H. F. Harlow

8 isolate monkeys were compared in a follow-up study to 8 sophisticated controls in brief cross-sectional pairings with 12 stimulus strangers: 4 adults, 4 age-mates, and 4 juveniles. The isolates were characterized by infantile disturbance, less environmental orality, more fear, more aggression, less sex, less play, and bizarre ritualistic movements. 12-mo. isolates were fearful and nonaggressive but threatened many attacks. 6-mo. isolates were fearful and physically aggressive. The 12-mo. isolates demonstrated practically no positive social behavior. Conclusions are: (a) 6 mo. of social isolation during the first year has negative effects on social behavior up to puberty, (b) abnormal aggression appears in 3-yr.-old 6-mo. isolates, and (c) 12 mo. of isolation suppress or delay this aggression.


1986 ◽  
Vol 64 (6) ◽  
pp. 527-533 ◽  
Author(s):  
Neelam Bansal ◽  
S Majumdar ◽  
NK Ganguly ◽  
RN Chakravarti

1990 ◽  
Vol 513 (1) ◽  
pp. 67-73 ◽  
Author(s):  
Mark H. Lewis ◽  
John P. Gluck ◽  
Alan J. Beauchamp ◽  
Michael F. Keresztury ◽  
Richard B. Mailman

2015 ◽  
Vol 78 (1) ◽  
pp. 152-166 ◽  
Author(s):  
Matthew J. Kessler ◽  
Qian Wang ◽  
Antonietta M. Cerroni ◽  
Marc D. Grynpas ◽  
Olga D. Gonzalez Velez ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Cari J. Bendersky ◽  
Allison A. Milian ◽  
Mason D. Andrus ◽  
Ubaldo De La Torre ◽  
Deena M. Walker

Adolescence is a period of incredible change, especially within the brain's reward circuitry. Stress, including social isolation, during this time has profound effects on behaviors associated with reward and other neuropsychiatric disorders. Because the Nucleus Accumbens (NAc), is crucial to the integration of rewarding stimuli, the NAc is especially sensitive to disruptions by adolescent social isolation stress. This review highlights the long-term behavioral consequences of adolescent social isolation rearing on the NAc. It will discuss the cellular and molecular changes within the NAc that might underlie the long-term effects on behavior. When available sex-specific effects are discussed. Finally by mining publicly available data we identify, for the first time, key transcriptional profiles induced by adolescence social isolation in genes associated with dopamine receptor 1 and 2 medium spiny neurons and genes associated with cocaine self-administration. Together, this review provides a comprehensive discussion of the wide-ranging long-term impacts of adolescent social isolation on the dopaminergic system from molecules through behavior.


2015 ◽  
Vol 76 (1) ◽  
pp. 34-46 ◽  
Author(s):  
Fábio C. Cruz ◽  
Josiane O. Duarte ◽  
Rodrigo M. Leão ◽  
Luiz F.V. Hummel ◽  
Cleopatra S. Planeta ◽  
...  

2020 ◽  
Vol 25 (4) ◽  
pp. 1-8
Author(s):  
Claire Hargrave

As the COVID-19 pandemic sweeps across the world, governments are taking unprecedented steps to achieve control and reduction of its affects. Although the potential mental and behavioural health challenges of social isolation for the human population has been widely discussed within the media, less has been said of the concurrent challenges faced by the companion animals that are also experiencing the regulations associated with ‘lock-down’ and ‘self-isolation’. This article considers the immediate consequences for dogs of reduced access to environmental and social stimulation outside the home and increased social exposure within the home, as well as considering some of the potential long-term effects of such measures.


1987 ◽  
Vol 113 (2) ◽  
pp. 355-363 ◽  
Author(s):  
S. Reinis ◽  
D.S. Weiss ◽  
J.W. Featherstone ◽  
C. Tsaros

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