A snare combined with endoclips to assist in endoscopic submucosal dissection for intraepithelial neoplasia in the entire colon and rectum

2019 ◽  
Vol 54 (1) ◽  
pp. 114-121 ◽  
Author(s):  
Qiang Zhang ◽  
Tong-Yin Xing ◽  
Zhen Wang
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Intraepithelial Neoplasia ◽  
Entire Colon ◽  
Submucosal Dissection ◽  
Colon And Rectum

Endoscopic submucosal dissection (ESD) for anal high-grade intraepithelial neoplasia: a case report

2018 ◽  
Vol 56 (05) ◽  
pp. 495-498 ◽  
Author(s):  
Daniel Neureiter ◽  
Josef Holzinger ◽  
Tobias Kiesslich ◽  
Eckhard Klieser ◽  
Frieder Berr ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Narrow Band Imaging ◽  
Anal Carcinoma ◽  
Intraepithelial Neoplasia ◽  
High Grade ◽  
Recurrence Rates ◽  
En Bloc ◽  
Submucosal Dissection ◽  
Very High

AbstractAnal intraepithelial neoplasia (AIN) is a precursor of anal carcinoma. Conventional therapy is based on topical and local ablative approaches. However, the recurrence rates are very high, leading to repetitive treatment sessions and need for long-term surveillance. Endoscopic submucosal dissection (ESD) is an established treatment for malignant early neoplasias of the gastrointestinal tract, especially in the esophagus, stomach, and colorectum. Japanese centers have reported few cases of ESD for early anal carcinoma. We report a case of high-grade AIN diagnosed with magnifying narrow-band imaging and chromoendoscopy that was resected R0 with ESD en bloc.

scholarly journals Comparative analysis of differences between preoperative endoscopic biopsy and postoperative pathological examination for diagnosis of gastric intraepithelial neoplasia

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199492
Author(s):  
Yangqing Wu ◽  
Jianzhong Sang ◽  
Jianbo Zhou ◽  
Ying Fang
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Intraepithelial Neoplasia ◽  
Endoscopic Biopsy ◽  
Pathological Examination ◽  
Low Grade ◽  
High Grade ◽  
Original Diagnosis ◽  
Submucosal Dissection ◽  
Low Grade Dysplasia ◽  
Pathological Tissues

Objective This study was performed to compare the differences between preoperative endoscopic biopsy (PEB) and postoperative pathological examination (PPE) for diagnosis of gastric intraepithelial neoplasia (GIN). Methods From September 2016 to July 2019, 188 consecutive patients with GIN at Yuyao People’s Hospital were retrospectively analyzed. The 188 patients had 218 GIN lesions. All patients underwent PEB and either endoscopic submucosal dissection or surgical treatment. PPE was performed on pathological tissues that had been surgically removed. Results Among 138 cases of low-grade dysplasia (LGD) diagnosed by PEB, 46 were upgraded to high-grade dysplasia (HGD), 20 were upgraded to early gastric cancer (EGC), and 2 were downgraded to inflammation after PPE. Among 42 cases of HGD, 23 were upgraded to EGC, 2 were downgraded to LGD, and 2 were downgraded to inflammation after PPE. Among 38 cases of EGC, 1 was downgraded to HGD and 2 were downgraded to LGD after PPE. The original diagnosis was maintained after the operation in 120 cases of GIN. Conclusion Biopsy did not fully reflect the lesions of GIN. Biopsy review should be actively performed, and the lesions should be clarified by endoscopic submucosal dissection or surgery.

Tu1718 Clinical Features of Pharyngeal Intraepithelial Neoplasia and Outcomes of Treatment by Endoscopic Submucosal Dissection

2012 ◽  
Vol 75 (4) ◽  
pp. AB499
Author(s):  
Shiro Oka ◽  
Shinji Tanaka ◽  
Takayasu Kuwabara ◽  
Yuji Urabe ◽  
Shigeto Yoshida ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Clinical Features ◽  
Intraepithelial Neoplasia ◽  
Submucosal Dissection

scholarly journals First experience of one and two-step endoscopic submucosal dissection of colorectal neoplasms

2020 ◽  
Vol 101 (3) ◽  
pp. 446-451
Author(s):  
I M Sayfutdinov ◽  
L E Slavin ◽  
R N Khayrullin ◽  
M S Mukharyamov ◽  
R T Zimagulov ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Colorectal Neoplasms ◽  
Intraoperative Complications ◽  
Intraepithelial Neoplasia ◽  
Intestinal Wall ◽  
Colorectal Polyps ◽  
Low Grade ◽  
En Bloc ◽  
Submucosal Dissection

Aim. To analyze the results of one and two-step endoscopic submucosal dissection in the treatment of colorectal neoplasms. Methods. Between 2018 and 2019, 17 patients (6 men and 11 women) aged 33 to 79 years underwent 21 endoscopic submucosal dissections of colorectal neoplasms ranging in size from 1.0 to 6.0 cm. Submucosal fibrosis was identified in 2 (11.8%) patients, epithelial neoplasms in 15 (88.2%) patients including laterally spreading tumors in 9 (60%), and large sessile colorectal polyps in 6 (40%) patients. Histological examination revealed a carcinoid tumor (11.8%), adenoma with low-grade (64.7%) and high-grade (23.5%) intraepithelial neoplasia. 13 patients were subjected to the one-step operation, and 4 patients required the two-step operation with a 1-day interval. Follow-up examinations after the operation were performed, on average, between 2 and 6 months. Results. En bloc endoscopic submucosal dissection was performed in 11 (64.7%) patients, 4 of them in combination with mucosal resection. Endoscopic piecemeal resection of the neoplasia was performed in 6 (35.3%) patients. The average operative time was 15573 minutes (range 40320 min). Intraoperative complications, which were eliminated endoscopically, occurred during 8 (38.1%) of 21 operations: intensive bleeding in 6 (75%) patients, diastasis of muscle fibers in 1 (12.5%) patient, perforation of the intestinal wall in 1 (12.5%) patient. At the follow-up at 6 months, all patients formed the scar at the surgical area, while 3 patients required endoscopic removal of residual adenoma 2 months after the operation. Conclusion. Endoscopic submucosal dissection is an effective method for removing colorectal neoplasms, while two-step dissection is a promising approach to the development of the technique.Keywords: one and two-step dissection, endoscopic submucosal dissection (ESD), colorectal neoplasms.

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