Individualism and Local Control

1994 ◽  
Vol 20 ◽  
pp. 185-205
Author(s):  
Ronald de Sousa

In both biology and psychology, the notion of an individual is indispensable yet puzzling. It has played a variety of roles in diverse contexts, ranging from philosophical problems of personal identity to scientific questions about the immunological mechanisms for telling ‘self’ from ‘non-self.’ There are notorious cases in which the question of individuality is difficult to settle — ant hill, slime mold, or beehive, for instance. Yet the notion of an individual organism, both dependent on and independent of other individuals in specific ways, is crucial to our conception of life itself. It is also crucial to our notion of mentality, and hence to other concepts — moral and social — which must be explicated in terms of individual mentality. (Think, for example, of the importance of the quality and nature of individual consciousness to debates about abortion and euthanasia.)

Etyka ◽  
1969 ◽  
Vol 4 ◽  
pp. 119-138
Author(s):  
Tadeusz Jaroszewski

The article makes a critical assessment if Heidegger’s conception of an authentic life. After presenting a number of social reasons which account for the current expansion of anthropological problems within philosophy, the author observes that the criticism of contemporary philosophical anthropologies – first and foremost of existentialism – is one of the fundamental tasks confronting the marxist philosophy. The reason for the critical studies on existentialism rests not only in the fact of its dealing with certain problems arising in definite social circun1stances, which, incidentally, marxism has to face too, but also because the problems of the philosophy of man are an integral part of Marxism itself, and have so far been rather neglected. The author further presents the basic tents of Heidegger’s philosophy, his conception of atheism, the thesis of human solitude and the necessity of making choice without a chance of learning beforehand anything about the things to be chosen. He lays the main stress on the problems of an „authentic life”. As Heidegger put it, the authentic life is nothing else but our courage to face the whole truth about our existence. An authentic man is he who „realises that he is a nonentity, and from that position evaluates his whole life”. Only the authentic man is free in the full meaning of the word, „since he knows that all he has achieved will eventually be blotted out, that he is alone and condemned to death”. Therefore, terror and anxiety constitute the essence of our existence. Understanding of the essence of death and conscious acceptance of fear and the necessity of choice determine our freedom. Living through our existence, understood as being-to-death (Sein-zum-Tode), delivers us from the non-authentic life. That is how – concludes the author – rebelling against the bourgeois-style life, which strips a man of his identity is reduced to the dimension of the deliverance within an individual consciousness – „an apparent deliverance”, as Marx put it while criticizing Stirner’s nihilism, to which Mounier added the term „the alienation of Narcissus” – the deliverance which emancipates an individual not only from „conformism resulting from living in a community”, but also life understood as a realisation of life itself through social expression. What only remains is the sense of nullity of one’s own existence. That is how the rebellion turned into a self-contradicting value – freedom became synonymous with the alienation of inter-human ties. The alienation of individuals, the sense of absurdity of everything that surrounds them, and questioning and subsequent rejection of all social value and forms – all this has been advanced to the rank of a virtue, and recognized as the hallmark of freedom and the „authentic life”.


Author(s):  
Ulrich Dierkes

Calcium is supposed to play an important role in the control of protoplasmic streaming in slime mold plasmodia. The motive force for protoplasmic streaming is generated by the interaction of actin and myosin. This contraction is supposed to be controlled by intracellular Ca-fluxes similar to the triggering system in skeleton muscle. The histochemical localisation of calcium however is problematic because of the possible diffusion artifacts especially in aquous media.To evaluate this problem calcium localisation was studied in small pieces of shock frozen (liquid propane at -189°C) plasmodial strands of Physarum polycephalum, which were further processed with 3 different methods: 1) freeze substitution in ethanol at -75°C, staining in 100% ethanol with 1% uranyl acetate, and embedding in styrene-methacrylate. For comparison the staining procedure was omitted in some preparations. 2)Freeze drying at about -95°C, followed by immersion with 100% ethanol containing 1% uranyl acetate, and embedding. 3) Freeze fracture, carbon coating and SEM investigation at temperatures below -100° C.


Author(s):  
W.G. Wier

A fundamentally new understanding of cardiac excitation-contraction (E-C) coupling is being developed from recent experimental work using confocal microscopy of single isolated heart cells. In particular, the transient change in intracellular free calcium ion concentration ([Ca2+]i transient) that activates muscle contraction is now viewed as resulting from the spatial and temporal summation of small (∼ 8 μm3), subcellular, stereotyped ‘local [Ca2+]i-transients' or, as they have been called, ‘calcium sparks'. This new understanding may be called ‘local control of E-C coupling'. The relevance to normal heart cell function of ‘local control, theory and the recent confocal data on spontaneous Ca2+ ‘sparks', and on electrically evoked local [Ca2+]i-transients has been unknown however, because the previous studies were all conducted on slack, internally perfused, single, enzymatically dissociated cardiac cells, at room temperature, usually with Cs+ replacing K+, and often in the presence of Ca2-channel blockers. The present work was undertaken to establish whether or not the concepts derived from these studies are in fact relevant to normal cardiac tissue under physiological conditions, by attempting to record local [Ca2+]i-transients, sparks (and Ca2+ waves) in intact, multi-cellular cardiac tissue.


Author(s):  
K.I. Pagh ◽  
M.R. Adelman

Unicellular amoebae of the slime mold Physarum polycephalum undergo marked changes in cell shape and motility during their conversion into flagellate swimming cells (l). To understand the processes underlying motile activities expressed during the amoebo-flagellate transformation, we have undertaken detailed investigations of the organization, formation and functions of subcellular structures or domains of the cell which are hypothesized to play a role in movement. One focus of our studies is on a structure, termed the “ridge” which appears as a flattened extension of the periphery along the length of transforming cells (Fig. 1). Observations of live cells using Nomarski optics reveal two types of movement in this region:propagation of undulations along the length of the ridge and formation and retraction of filopodial projections from its edge. The differing activities appear to be associated with two characteristic morphologies, illustrated in Fig. 1.


2004 ◽  
Vol 171 (4S) ◽  
pp. 385-385 ◽  
Author(s):  
Carl K. Gjertson ◽  
Kevin P. Asher ◽  
Joshua D. Sclar ◽  
Aaron E. Katz ◽  
Erik T. Goluboff ◽  
...  

PsycCRITIQUES ◽  
1985 ◽  
Vol 30 (12) ◽  
Author(s):  
Ralph H. Turner

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