scholarly journals Tissue and interspecies comparison of catechol-O-methyltransferase mediated catalysis of 6-O-methylation of esculetin to scopoletin and its inhibition by entacapone and tolcapone

Xenobiotica ◽  
2020 ◽  
pp. 1-11
Author(s):  
Aaro Jalkanen ◽  
Veera Lassheikki ◽  
Tommi Torsti ◽  
Elham Gharib ◽  
Marko Lehtonen ◽  
...  
Keyword(s):  
Interspecies Comparison ◽  
Mediated Catalysis

scholarly journals The Profound Influence of Lipid Composition on the Catalysis of the Drug Target NADH Type II Oxidoreductase

Membranes ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 363
Author(s):  
Albert Godoy-Hernandez ◽  
Duncan G. G. McMillan
Keyword(s):  
Acyl Chain ◽  
Cellular Respiration ◽  
Type Ii ◽  
Nadh:Quinone Oxidoreductase ◽  
Chain Composition ◽  
Membrane Bound ◽  
Lipid Environment ◽  
Lipid Specificity ◽  
Mediated Catalysis ◽  
Quinone Pool

Lipids play a pivotal role in cellular respiration, providing the natural environment in which an oxidoreductase interacts with the quinone pool. To date, it is generally accepted that negatively charged lipids play a major role in the activity of quinone oxidoreductases. By changing lipid compositions when assaying a type II NADH:quinone oxidoreductase, we demonstrate that phosphatidylethanolamine has an essential role in substrate binding and catalysis. We also reveal the importance of acyl chain composition, specifically c14:0, on membrane-bound quinone-mediated catalysis. This demonstrates that oxidoreductase lipid specificity is more diverse than originally thought and that the lipid environment plays an important role in the physiological catalysis of membrane-bound oxidoreductases.

The First Thiadiazolidine 1-Oxide System for Phosphine-Free Palladium-Mediated Catalysis

2009 ◽  
Vol 351 (1-2) ◽  
pp. 71-77 ◽  
Author(s):  
Benjamin R. Buckley ◽  
Stephen P. Neary
Keyword(s):  
Oxide System ◽  
Mediated Catalysis

A family of complex tandem DNA repeats in the telomeres of Chironomus pallidivittatus

1994 ◽  
Vol 14 (12) ◽  
pp. 8028-8036
Author(s):  
Y J Zhang ◽  
I Kamnert ◽  
C C López ◽  
M Cohn ◽  
J E Edström
Keyword(s):  
Special Kind ◽  
Single Strand ◽  
Dna Repeats ◽  
Interspecies Comparison ◽  
Functional Roles ◽  
Paired Chromosome ◽  
Selective Forces ◽  
Small Clusters ◽  
Dyad Symmetry ◽  
Complex Block

A family of 340-bp tandem telomere-associated DNA repeats is present in 50- to 200-kb blocks in seven of the eight paired chromosome ends in Chironomus pallidivittatus. It consists of four main subfamilies, differing from each other by small clusters of mutations. This differentiation may reflect different functional roles for the repeats. Here we find that one subfamily, D3, is consistently localized most peripherally and extends close to the ends of the chromosomes, as shown by its sensitivity to the exonuclease Bal 31. The amounts of D3 are highly variable between individuals. The repeat characteristic for D3 forms a segment with pronounced dyad symmetry, which in single-strand form would give rise to a hairpin. Evidence from an interspecies comparison suggests that a similar structure is the result of selective forces. Another subfamily, M1, is present more proximally in a subgroup of telomeres characterized by a special kind of repeat variability. Thus, a complex block with three kinds of subfamilies may occupy different M1 telomeres depending on the stock of animals. We conclude that subfamilies are differentially distributed between and within telomeres and are likely to serve different functions.

scholarly journals Thiadiazolidine 1-oxide systems for phosphine-free palladium-mediated catalysis

Tetrahedron ◽  
2010 ◽  
Vol 66 (40) ◽  
pp. 7988-7994 ◽  
Author(s):  
Benjamin R. Buckley ◽  
Stephen P. Neary
Keyword(s):  
Oxide Systems ◽  
Mediated Catalysis

scholarly journals Interspecies comparison of stellate cell-containing macula flavae and vitamin A storage in vocal fold mucosa

2014 ◽  
Vol 225 (3) ◽  
pp. 298-305 ◽  
Author(s):  
Yutaka Toya ◽  
Napaporn Riabroy ◽  
Christopher R. Davis ◽  
Yo Kishimoto ◽  
Sherry A. Tanumihardjo ◽  
...  
Keyword(s):  
Vitamin A ◽  
Vocal Fold ◽  
Stellate Cell ◽  
Interspecies Comparison

Coupling Solar Energy into Reactions: Materials Design for Surface Plasmon-Mediated Catalysis

Small ◽  
2015 ◽  
Vol 11 (32) ◽  
pp. 3873-3889 ◽  
Author(s):  
Ran Long ◽  
Yu Li ◽  
Li Song ◽  
Yujie Xiong
Keyword(s):  
Solar Energy ◽  
Surface Plasmon ◽  
Materials Design ◽  
Mediated Catalysis
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