Some Bryophytes Trigger Cytotoxicity of Stem Cell-like Population in 5-Fluorouracil Resistant Colon Cancer Cells

2021 ◽  
pp. 1-11
Author(s):  
Dilşad Özerkan ◽  
Ayşe Erol ◽  
Ergin Murat Altuner ◽  
Kerem Canlı ◽  
Dürdane Serap Kuruca
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Cells ◽  
Colon Cancer Cells

Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture

2018 ◽  
Vol 375 (3) ◽  
pp. 697-707 ◽  
Author(s):  
Kanji Hirashima ◽  
Fengming Yue ◽  
Mikiko Kobayashi ◽  
Yuriko Uchida ◽  
Shunsuke Nakamura ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cancer Cells ◽  
Colon Cancer Cells

Inhibition of 3D colon cancer stem cell spheroids by cytotoxic RuII-p-cymene complexes of mesalazine derivatives

2020 ◽  
Vol 56 (40) ◽  
pp. 5421-5424
Author(s):  
Sourav Acharya ◽  
Subhashis Ghosh ◽  
Moumita Maji ◽  
Ajmal Roshan Unniram Parambil ◽  
Sandeep Singh ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cancer Cells ◽  
Colon Cancer Cells ◽  
Cell Spheroids ◽  
Colon Cancer Stem Cell

RuII-p-cymene complexes of imidazole–mesalazine based ligands kill bulk and stem colon cancer cells with tight regulation over stemness markers.

scholarly journals Induction of Cancer Stem Cell Properties in Colon Cancer Cells by Defined Factors

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e101735 ◽  
Author(s):  
Nobu Oshima ◽  
Yasuhiro Yamada ◽  
Satoshi Nagayama ◽  
Kenji Kawada ◽  
Suguru Hasegawa ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cancer Cells ◽  
Colon Cancer Cells

Bone Marrow Mesenchymal Stem Cell (BMSC)-Derived Exosomes Increase Colon Cancer Cell Apoptosis and Inhibit Proliferation and Migration

2021 ◽  
Vol 11 (10) ◽  
pp. 1918-1923
Author(s):  
Xinfa Zhang ◽  
Cheng Han
Keyword(s):  
Bone Marrow ◽  
Colon Cancer ◽  
Stem Cell ◽  
Electron Microscope ◽  
Mesenchymal Stem Cell ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Colon Cancer Cell ◽  
Colon Cancer Cells

This study aims to investigate whether bone marrow mesenchymal stem cell (BMSC) exosomes (BMSC-exos) affects the progression of colon cancer. Ultracentrifugation was used to extract and collect BMSC-exos which were assessed under electron microscope and by flow cytometry. The BMSCs were divided into two groups: control group treated with α-MEM basal medium and experimental group with exosomes (10 μg/ml). Exos were extracted from BMSCs and co-cultured with colon cancer cells, followed by analysis of cell viability by CCK-8 assay and GLUT3 mRNA and protein expression by RT-qPCR and Western blot. The electron microscope analysis indicated that the primary BMSCs showed a long spindle shape with a negative expression of antigen CD34 and positive antigen CD90. Importantly, exos inhibited the viability of colon cancer cells HCT116 and decreased the expression of GLUT3, suggesting that exos might increase the colon cancer cell apoptosis. In conclusion, BMSC-exos inhibit cell progression in colon cancer and might be served as a promising biomarker.

scholarly journals Direct reprogramming of stem cell properties in colon cancer cells by CD44

2011 ◽  
Vol 30 (15) ◽  
pp. 3186-3199 ◽  
Author(s):  
Ying-Jhen Su ◽  
Hsin-Mei Lai ◽  
Yi-Wen Chang ◽  
Guan-Ying Chen ◽  
Jia-Lin Lee
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Cancer Cells ◽  
Direct Reprogramming ◽  
Colon Cancer Cells

scholarly journals HMGA1 Induces Intestinal Polyposis in Transgenic Mice and Drives Tumor Progression and Stem Cell Properties in Colon Cancer Cells

PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e30034 ◽  
Author(s):  
Amy Belton ◽  
Alexander Gabrovsky ◽  
Young Kyung Bae ◽  
Ray Reeves ◽  
Christine Iacobuzio-Donahue ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Stem Cell ◽  
Transgenic Mice ◽  
Tumor Progression ◽  
Cancer Cells ◽  
Intestinal Polyposis ◽  
Colon Cancer Cells
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