Recent developments in the diagnosis and treatment of subcutaneous mycoses

1994 ◽  
Vol 32 (s1) ◽  
pp. 299-307 ◽  
Author(s):  
H.S. Randhawa ◽  
U. Budimulja ◽  
G. Bazaz-Malik ◽  
K. Bramono ◽  
M. Hiruma ◽  
...  
1986 ◽  
Vol 7 (9) ◽  
pp. 276-286
Author(s):  
Robert C. Stern

Advances in diagnosis and treatment of cystic fibrosis have greatly extended life expectancy and have decreased morbidity. However, further progress requires knowledge of the fundamental genetic defect and how it is related to the pulmonary pathophysiology. Major new developments in both these areas are likely within the next 5 to 10 years.


Author(s):  
Jeanny B. Aragon-Ching ◽  
Lance C. Pagliaro

The diagnosis and treatment of rare genitourinary tumors is inherently challenging. The Rare Diseases Act of 2002 initially defined a rare disorder as one that affects fewer than 200,000 Americans. The lack of widely available clinical guidelines, limited research funding, and inaccessible clinical trials often lead to difficulty with treatment decisions to guide practitioners in rendering effective care for patients with rare genitourinary cancers. This article will discuss basic tenets of diagnosis and treatment as well as recent developments and clinical trials in rare non-urothelial bladder cancers and penile squamous cell cancers.


1985 ◽  
Vol 36 (9) ◽  
pp. 951-957 ◽  
Author(s):  
Robert L. Williams ◽  
Ismet Karacan

1998 ◽  
Vol 59 (2) ◽  
pp. 194-202 ◽  
Author(s):  
M. Patriarca ◽  
A. Menditto ◽  
G. Di Felice ◽  
F. Petrucci ◽  
S. Caroli ◽  
...  

2015 ◽  
Vol 279 (1) ◽  
pp. 16-29 ◽  
Author(s):  
T. van der Hulle ◽  
C. E. A. Dronkers ◽  
F. A. Klok ◽  
M. V. Huisman

Nanomedicine ◽  
2019 ◽  
Vol 14 (19) ◽  
pp. 2613-2629 ◽  
Author(s):  
Veruscka Leso ◽  
Luca Fontana ◽  
Maria Luigia Ercolano ◽  
Rosaria Romano ◽  
Ivo Iavicoli

Nanotechnology may offer innovative solutions to overcome the physiological and anatomical barriers that make the diagnosis and treatment of ear diseases an extremely challenging issue. However, despite the solutions provided by nano-applications, the still little-known toxicological behavior of nanomaterials raised scientific concerns regarding their biosafety for treated patients and exposed workers. Therefore, this review provides an overview on recent developments and upcoming opportunities in nanoscale otological applications, and critically assesses possible adverse effects of nanosized compounds on ear structures and hearing functionality. Although such preliminary data do not allow to draw definite strategies for the evaluation of nanomaterial ototoxicity, they can still be useful to improve scientific community and workforce awareness regarding possible nanomaterial adverse effects on ear.


Cells ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 2334
Author(s):  
Amelie Heesch ◽  
Jochen Maurer ◽  
Elmar Stickeler ◽  
Mohsen Beheshti ◽  
Felix M. Mottaghy ◽  
...  

Molecular imaging plays an increasingly important role in the diagnosis and treatment of different malignancies. Radiolabeled probes enable the visualization of the primary tumor as well as the metastases and have been also employed in targeted therapy and theranostic approaches. With breast cancer being the most common malignancy in women worldwide it is of special interest to develop novel targeted treatments. However, tumor microenvironment and escape mechanisms often limit their therapeutic potential. Addressing tumor stroma associated targets provides a promising option to inhibit tumor growth and angiogenesis and to disrupt tumor tissue architecture. This review describes recent developments on radiolabeled probes used in diagnosis and treatment of breast cancer especially in triple negative type with the focus on potential targets offered by the tumor microenvironment, like tumor associated macrophages, cancer associated fibroblasts, and endothelial cells.


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