Unbiasedness of two-stage estimation and prediction procedures for mixed linear models

1981 ◽  
Vol 10 (13) ◽  
pp. 1249-1261 ◽  
Author(s):  
Raghu N. Kackar ◽  
David A. Harville
2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Arvid Sjolander ◽  
Torben Martinussen

Abstract Instrumental variables is a popular method in epidemiology and related fields, to estimate causal effects in the presence of unmeasured confounding. Traditionally, instrumental variable analyses have been confined to linear models, in which the causal parameter of interest is typically estimated with two-stage least squares. Recently, the methodology has been extended in several directions, including two-stage estimation and so-called G-estimation in nonlinear (e. g. logistic and Cox proportional hazards) models. This paper presents a new R package, ivtools, which implements many of these new instrumental variable methods. We briefly review the theory of two-stage estimation and G-estimation, and illustrate the functionality of the ivtools package by analyzing publicly available data from a cohort study on vitamin D and mortality.


1998 ◽  
Vol 55 (2) ◽  
pp. 291-295
Author(s):  
L.A. LÓPEZ ◽  
A.F. IEMMA

Beginning with the classical Gauss-Markov Linear Model for mixed effects and using the technique of the Lagrange multipliers to obtain an alternative method for the estimation of linear predictors. A structural method is also discussed in order to obtain the variance and covariance matrixes and their inverses.


2013 ◽  
Vol 38 (4) ◽  
pp. 624-631
Author(s):  
Chang-You LIU ◽  
Bao-Jie FAN ◽  
Zhi-Min CAO ◽  
Yan WANG ◽  
Zhi-Xiao ZHANG ◽  
...  

1990 ◽  
Vol 73 (6) ◽  
pp. 1612-1624 ◽  
Author(s):  
J.L. Foulley ◽  
D. Gianola ◽  
M. San Cristobal ◽  
S. Im

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