Nuchal Translucency Thickness Measurement in Fetal Ultrasound Images to Analyze Down Syndrome

2021 ◽  
pp. 1-11
Author(s):  
Mary Christeena Thomas ◽  
Sridhar P. Arjunan ◽  
Rekha Viswanathan
2004 ◽  
Vol 24 (3) ◽  
pp. 243-243
Author(s):  
D. K. Nassiri ◽  
V. R. Newey ◽  
A. Bhide ◽  
B. Thilaganathan

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Barmak Honarvar Shakibaei Asli ◽  
Yifan Zhao ◽  
John Ahmet Erkoyuncu

AbstractHigh-quality medical ultrasound imaging is definitely concerning motion blur, while medical image analysis requires motionless and accurate data acquired by sonographers. The main idea of this paper is to establish some motion blur invariant in both frequency and moment domain to estimate the motion parameters of ultrasound images. We propose a discrete model of point spread function of motion blur convolution based on the Dirac delta function to simplify the analysis of motion invariant in frequency and moment domain. This model paves the way for estimating the motion angle and length in terms of the proposed invariant features. In this research, the performance of the proposed schemes is compared with other state-of-the-art existing methods of image deblurring. The experimental study performs using fetal phantom images and clinical fetal ultrasound images as well as breast scans. Moreover, to validate the accuracy of the proposed experimental framework, we apply two image quality assessment methods as no-reference and full-reference to show the robustness of the proposed algorithms compared to the well-known approaches.


Diagnosis ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Elham Kebriyaei ◽  
Ali Davoodi ◽  
Seyed Alinaghi Kazemi ◽  
Zahra Bazargani

Abstract Objectives Renal anomalies are the most common fetal abnormalities that occur during prenatal development, and are typically detected by observing hydronephrosis on fetal ultrasound imaging. Follow-up with post-natal ultrasound is important to detect clinically-important obstruction, because many of the pre-natal abnormalities resolve spontaneously. This study aimed to evaluate the postnatal hydronephrosis follow-up rate, and reasons for non follow-up in affected neonates. Methods In this cross-sectional study all neonates born during a period of one year at Ayatollah Mousavi Hospital with hydronephrosis on fetal ultrasound imaging were recruited. All mothers were also given face-to-face information about fetal hydronephrosis and its postnatal outcomes, and follow-up with at least a postnatal ultrasound was recommended from the fourth day of their neonates’ birth until the end of the fourth week. The neonates were subsequently observed for one month to determine the postnatal ultrasound follow-up rate and to reflect on diagnostic test results, reasons for failure to follow-up, as well as causes of hydronephrosis. Results In this study, 71 cases (1.2%) out of 5,952 neonates had fetal hydronephrosis on prenatal ultrasound images. The postnatal ultrasound imaging showed kidney involvement in 18 neonates (25%), particularly in the left kidney (61.1%). Seven neonates had no follow-up at one month (10%). No significant relationship was found between lack of follow-up and the neonates’ place of residence (p=0.42), maternal education (p=0.90), number of siblings (p=0.33), or gender (p=0.64). Conclusions Postnatal ultrasound follow-up rate in these neonates with a history of fetal hydronephrosis was incomplete even though parents had been provided with education and advice at their birth time. Accordingly, it is recommended to perform postnatal ultrasound once neonates are discharged from hospitals.


2010 ◽  
Vol 134 (11) ◽  
pp. 1685-1691
Author(s):  
Glenn E. Palomaki ◽  
George J. Knight ◽  
Geralyn Lambert-Messerlian ◽  
Jacob A. Canick ◽  
James E. Haddow

Abstract Context.—We initiated a voluntary, self-funded interlaboratory comparison program in the fall of 2005 because no proficiency testing program was available to laboratories in North America offering first-trimester, combined serum and ultrasound, Down syndrome screening. Objectives.—To evaluate the first 4 years of the interlaboratory comparison program against stated goals, to identify areas of concern, and to create new initiatives as indicated. Design.—Five serum samples are distributed 3 times a year to be tested for pregnancy-associated plasma protein A, human chorionic gonadotropin or its β subunit, and dimeric inhibin-A; participants convert these results into multiples of the median. Patient histories include nuchal translucency information that enables the calculation of the risk of Down syndrome. Also included are educational components linked to interlaboratory comparison program results. Assessment of integrated (first- and second-trimester markers) risks is accomplished by having participants combine interlaboratory comparison program results with their results from a second-trimester proficiency testing program administered by the College of American Pathologists. Results.—The precision profile for pregnancy-associated plasma protein A shows decreasing coefficients of variation with increasing pregnancy-associated plasma protein A concentrations and multiples of the median (25% to 11% and 30% to 15%, respectively). In contrast, coefficients of variation are a relatively constant 12% throughout the entire range of human chorionic gonadotropin results. On a logarithmic scale, the median coefficient of variation of the risk of Down syndrome is 9%. Conclusions.—Participants in the interlaboratory comparison program reliably measure analytes, compute multiples of the median, and calculate consistent Down syndrome risks. Assays for the measurement of pregnancy-associated plasma protein A are not standardized and are less precise than those for human chorionic gonadotropin. Participants calculate reliable median equations given sonographer-specific sets of paired crown-rump length and nuchal translucency measurements.


Ultrasound ◽  
2008 ◽  
Vol 16 (4) ◽  
pp. 220-225 ◽  
Author(s):  
Debbie Nisbet

In some countries, measurement of nuchal translucency (NT) is incorporated into national antenatal screening programmes to help detect pregnancies at increased risk of Down syndrome. Accurate measurement of the NT requires a specific technique. This article is an illustrated practical guide outlining the steps required for measuring the NT; it provides useful tips for improving operator technique and advises how to avoid common pitfalls. Although fetal nasal bone assessment does not currently form part of official Down syndrome screening programmes (in Australia or the UK), it is included here as debate about its usefulness continues.


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